• 1. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 2. Excitonic channels from bio-inspired templated supramolecular assembly of J-aggregate nanowires?
  Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
• 3. Establishment and implications of a characterization method for magnetic nanoparticle using cell tracking velocimetry and magnetic susceptibility modified solutions
  Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
• 4. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 5. Fe3O4 nanosphere@microporous organic networks: enhanced anode performances in lithium ion batteries through carbonization?
  Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726

Introduction to Triclocarban-d4 (4-chlorophenyl-d4): CAS No. 1219799-29-7

Triclocarban-d4 (4-chlorophenyl-d4), with the CAS number 1219799-29-7, is a deuterated analog of triclocarban, a widely studied compound in the field of environmental and biomedical research. This compound is particularly valuable for its stable isotope labeling, which facilitates detailed studies in various scientific disciplines, including pharmacology, toxicology, and environmental science.

The chemical structure of Triclocarban-d4 (4-chlorophenyl-d4) is characterized by the presence of four deuterium atoms on the phenyl ring, which replaces the hydrogen atoms. This deuterium substitution provides enhanced stability and distinct spectral properties, making it an ideal candidate for high-resolution analytical techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy.

In recent years, the use of deuterated compounds like Triclocarban-d4 (4-chlorophenyl-d4) has gained significant attention due to their applications in tracing studies and metabolic profiling. Deuterium-labeled compounds are often used to track the fate and behavior of molecules in complex biological systems, providing insights into their metabolism, distribution, and potential interactions with other biomolecules.

One of the key areas where Triclocarban-d4 (4-chlorophenyl-d4) has been extensively studied is in environmental monitoring. Triclocarban, a common antimicrobial agent found in personal care products, has been detected in various environmental matrices such as water, soil, and sediments. The deuterated form of triclocarban allows researchers to differentiate between natural and anthropogenic sources of this compound, thereby aiding in the assessment of environmental contamination and the effectiveness of remediation strategies.

In the realm of pharmacology and toxicology, Triclocarban-d4 (4-chlorophenyl-d4) serves as a valuable tool for understanding the pharmacokinetics and toxicodynamics of triclocarban. Studies have shown that triclocarban can exhibit endocrine-disrupting properties and may have adverse effects on aquatic organisms. By using deuterated triclocarban, researchers can more accurately measure its bioaccumulation and biotransformation processes in living organisms.

The stability and distinct isotopic signature of Triclocarban-d4 (4-chlorophenyl-d4) also make it suitable for use in clinical research. In clinical trials, deuterated compounds are often employed to monitor drug metabolism and evaluate the efficacy and safety of new therapeutic agents. The ability to track these compounds with high precision enhances the reliability of clinical data and supports the development of more effective treatments.

Beyond its applications in research, Triclocarban-d4 (4-chlorophenyl-d4) has potential implications for regulatory science. Regulatory agencies often require detailed information on the environmental fate and health effects of chemicals used in consumer products. Deuterated analogs like triclocarban can provide crucial data to inform risk assessments and guide policy decisions.

In conclusion, Triclocarban-d4 (4-chlorophenyl-d4), CAS No. 1219799-29-7, is a versatile compound with a wide range of applications in scientific research. Its unique properties make it an indispensable tool for advancing our understanding of environmental contamination, drug metabolism, and toxicological effects. As research continues to evolve, the importance of deuterated compounds like triclocarban will likely grow, contributing to more informed decision-making in both scientific and regulatory contexts.

• 2617-72-3(Urea,N-(3-chlorophenyl)-N'-(3,4-dichlorophenyl)-)
• 1007536-67-5(Diuron-d6)
• 2327-02-8(Didemethyldiuron)
• 94201-85-1(Urea,N-(3,4-dichlorophenyl)-N'-[3-(dimethylamino)phenyl]-)
• 13208-31-6(n,n'-bis(3-chlorophenyl)urea)
• 101-20-2(Triclocarban)
• 3567-62-2(N-Demethoxy Linuron)
• 2008-73-3(3-(3,4-dichlorophenyl)-1-phenylurea)
• 61208-38-6(Urea, N'-(3,4-dichlorophenyl)-N,N-dimethyl-, sodium salt)
• 330-54-1(Diuron)