Cas no 1217863-25-6 ({2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol)

{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol is an organosilicon compound featuring a chlorophenyl and hydroxymethyl functional group attached to a dimethylsilyl-substituted phenyl ring. This structure imparts unique reactivity, making it valuable as an intermediate in organic synthesis, particularly in the preparation of silane-based polymers, coatings, or pharmaceutical precursors. The chlorophenyl group enhances electrophilic substitution potential, while the silanol moiety offers versatility in crosslinking or functionalization reactions. Its stability under controlled conditions and compatibility with various coupling reagents make it suitable for advanced material science applications. The compound is typically handled under inert conditions to preserve its hydroxyl and silane functionalities.
{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol structure
1217863-25-6 structure
Product Name:{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol
CAS No:1217863-25-6
MF:C15H17ClOSi
MW:276.833384275436
MDL:MFCD16251551
CID:1071782
PubChem ID:57416887
Update Time:2025-05-19

{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol Chemical and Physical Properties

Names and Identifiers

    • {2-[(4-Chlorophenyl)dimethylsilyl]phenyl}methanol
    • 2-[(4-Chlorophenyl)dimethylsilyl]benzyl alcohol
    • [2-[(4-chlorophenyl)-dimethylsilyl]phenyl]methanol
    • AKOS025392266
    • MFCD16251551
    • CS-0442612
    • A921638
    • (2-((4-Chlorophenyl)dimethylsilyl)phenyl)methanol
    • DTXSID20726230
    • {2-[(4-Chlorophenyl)(dimethyl)silyl]phenyl}methanol
    • 1217863-25-6
    • AS-2212
    • [2-[(4-Chlorophenyl)-dimethylsilyl]phenyl]methanolIaaEIaaE
    • Homsi (r) p-chlorophenyl
    • {2-[(4-Chloro-phenyl)-dimethyl-silanyl]-phenyl}-methanol
    • {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol
    • MDL: MFCD16251551
    • Inchi: 1S/C15H17ClOSi/c1-18(2,14-9-7-13(16)8-10-14)15-6-4-3-5-12(15)11-17/h3-10,17H,11H2,1-2H3
    • InChI Key: YULOYAUMWFHYQS-UHFFFAOYSA-N
    • SMILES: ClC1C=CC(=CC=1)[Si](C)(C)C1C=CC=CC=1CO

Computed Properties

  • Exact Mass: 276.0737194g/mol
  • Monoisotopic Mass: 276.0737194g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 3
  • Complexity: 261
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 20.2?2

{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol Security Information

{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol Pricemore >>

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Additional information on {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol

Introduction to {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol (CAS No: 1217863-25-6)

{2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol is a sophisticated organic compound that has garnered significant attention in the field of pharmaceutical chemistry and materials science. This compound, identified by its CAS number 1217863-25-6, features a unique structural framework that combines a chlorophenyl group with a dimethylsilanyl moiety, linked to a phenyl-methanol backbone. The presence of these specific functional groups imparts distinct chemical properties that make it a valuable candidate for various applications, particularly in the development of novel drug candidates and advanced materials.

The molecular structure of {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol is characterized by its aromaticity and the presence of electron-withdrawing and electron-donating groups. The chlorophenyl ring introduces a chlorine atom, which can participate in various chemical reactions such as nucleophilic substitution, enhancing the compound's reactivity. Meanwhile, the dimethylsilanyl group provides steric hindrance and can influence the electronic properties of the molecule, making it useful in designing molecules with specific interactions.

Recent research in the field of medicinal chemistry has highlighted the potential of this compound as a building block for more complex molecules. Its structural features make it an excellent candidate for further derivatization, allowing chemists to explore new pharmacophores and optimize biological activity. For instance, studies have shown that derivatives of this compound can exhibit promising effects in modulating enzyme activity and receptor binding, which are crucial for developing new therapeutic agents.

In materials science, {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol has been investigated for its potential applications in organic electronics and polymer chemistry. The compound's ability to form stable intermediates and its compatibility with various synthetic methodologies make it a valuable precursor for synthesizing advanced materials. Researchers have explored its use in creating conductive polymers and organic semiconductors, which are essential components in flexible electronics and optoelectronic devices.

The synthesis of {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol involves multi-step organic reactions that require precise control over reaction conditions. The introduction of the chlorophenyl group typically involves halogenation reactions, while the attachment of the dimethylsilanyl moiety often requires organosilicon chemistry techniques. These synthetic pathways highlight the compound's complexity and the expertise required to produce it in high yields and purity.

One of the most intriguing aspects of this compound is its potential role in drug discovery. The combination of electronic and steric effects provided by its structure allows it to interact with biological targets in diverse ways. For example, researchers have hypothesized that derivatives of {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol could be effective in inhibiting certain enzymes or receptors implicated in diseases such as cancer and neurodegenerative disorders. Preliminary computational studies have suggested that modifications to this core structure could enhance binding affinity and selectivity.

The pharmacokinetic properties of {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol are also subjects of interest. Understanding how this compound is metabolized and distributed within the body is crucial for optimizing its therapeutic potential. Advanced spectroscopic techniques and computational modeling have been employed to study its interactions with biological systems, providing insights into its behavior as a drug candidate.

Furthermore, the environmental impact of synthesizing and using {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol is an important consideration. Efforts are being made to develop greener synthetic routes that minimize waste and reduce energy consumption. These initiatives align with broader trends in sustainable chemistry, where efficiency and environmental responsibility are prioritized alongside innovation.

The future prospects for {2-(4-Chloro-phenyl)-dimethyl-silanyl-phenyl}-methanol are promising, with ongoing research exploring its potential applications across multiple disciplines. As our understanding of molecular interactions grows, so does the potential for this compound to contribute to advancements in medicine and materials science. Collaborative efforts between chemists, biologists, and engineers will be essential in realizing these possibilities.

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