• 1. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 2. Establishing plasmon contribution to chemical reactions: alkoxyamines as a thermal probe?
  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 3. Dissociative electron attachment to HGaF4 Lewis–Br?nsted superacid
  Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
• 4. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
• 5. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147

• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Phenylpropanoic acids Phenylpropanoic acids
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Phenylpropanoic acids

Comprehensive Guide to rac 2-Hydroxy Ibuprofen-d6 (CAS No. 1217055-71-4): Properties, Applications, and Market Insights

rac 2-Hydroxy Ibuprofen-d6 (CAS No. 1217055-71-4) is a deuterated analog of the well-known nonsteroidal anti-inflammatory drug (NSAID) ibuprofen. This compound has gained significant attention in pharmaceutical research due to its unique isotopic labeling, which enhances its utility in drug metabolism studies, pharmacokinetics, and analytical chemistry. The deuterium-labeled version of 2-hydroxy ibuprofen provides researchers with a powerful tool for tracing metabolic pathways and improving the accuracy of mass spectrometry-based assays.

The growing demand for deuterated compounds like rac 2-Hydroxy Ibuprofen-d6 is driven by advancements in precision medicine and the need for more reliable biomarkers in clinical research. With the rise of personalized healthcare, researchers are increasingly focusing on understanding individual variations in drug metabolism, making compounds such as rac 2-Hydroxy Ibuprofen-d6 invaluable for developing targeted therapies. Additionally, the compound’s stability and isotopic purity make it a preferred choice for quantitative analysis in complex biological matrices.

From a chemical perspective, rac 2-Hydroxy Ibuprofen-d6 features six deuterium atoms strategically placed to maintain the compound’s structural integrity while enabling precise detection in analytical workflows. This modification does not alter the pharmacological activity of the parent molecule but significantly enhances its utility in isotope dilution mass spectrometry (IDMS) and other high-sensitivity techniques. The compound is particularly useful in studying the metabolic fate of ibuprofen, a drug widely used for pain relief and inflammation management.

In the pharmaceutical industry, rac 2-Hydroxy Ibuprofen-d6 is often employed as an internal standard in bioanalytical assays to ensure accurate quantification of ibuprofen and its metabolites in plasma, urine, and other biological samples. Its role in drug development and regulatory compliance cannot be overstated, as regulatory agencies increasingly require robust analytical methods for drug approval. The compound’s compatibility with LC-MS/MS (liquid chromatography-tandem mass spectrometry) further solidifies its position as a critical reagent in modern laboratories.

Market trends indicate a rising interest in deuterated pharmaceuticals, with rac 2-Hydroxy Ibuprofen-d6 being a prime example of this niche yet expanding sector. The global push toward sustainable chemistry and green synthesis has also influenced the production of deuterated compounds, with manufacturers adopting eco-friendly protocols to minimize environmental impact. Researchers and procurement specialists frequently search for high-purity rac 2-Hydroxy Ibuprofen-d6 suppliers, emphasizing the need for reliable sources that adhere to stringent quality standards.

Beyond its analytical applications, rac 2-Hydroxy Ibuprofen-d6 is also explored in mechanistic studies to elucidate the enzymatic pathways involved in ibuprofen metabolism. Understanding these pathways is crucial for predicting drug-drug interactions and optimizing therapeutic outcomes. The compound’s relevance extends to forensic toxicology, where it aids in the accurate detection and quantification of ibuprofen in post-mortem and clinical toxicology cases.

For laboratories and research institutions, sourcing rac 2-Hydroxy Ibuprofen-d6 with guaranteed isotopic enrichment and chemical purity is paramount. Suppliers often provide certificates of analysis (CoA) detailing parameters such as deuterium incorporation, residual solvents, and chromatographic purity. These quality assurances are critical for ensuring reproducible results in sensitive applications like clinical trials and pharmacokinetic modeling.

In summary, rac 2-Hydroxy Ibuprofen-d6 (CAS No. 1217055-71-4) is a versatile and indispensable tool in pharmaceutical and analytical research. Its unique properties cater to the evolving needs of drug discovery, metabolomics, and regulatory science, making it a sought-after compound in both academic and industrial settings. As the demand for deuterated standards continues to grow, rac 2-Hydroxy Ibuprofen-d6 remains at the forefront of innovation in analytical chemistry and beyond.

• 51146-55-5(2-Hydroxyibuprofen)
• 58560-75-1(Ibuprofen)
• 51146-56-6((S)-(+)-Ibuprofen)
• 66622-47-7(m-Isobutyl Ibuprofen)
• 51146-57-7((R)-(-)-Ibuprofen)
• 1216459-54-9(Ibuprofen-13C6)
• 121662-14-4(Ibuprofen-d)
• 53949-54-5(Hydroxy Ibuprofen)
• 15687-27-1(Ibuprofen)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)