Cas no 1215609-88-3 ((1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride)

1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride is a fluorinated sulfonamide derivative with a piperidine scaffold, commonly utilized as a versatile intermediate in pharmaceutical and organic synthesis. Its structural features, including the 4-fluorophenylsulfonyl group and primary amine functionality, make it valuable for designing bioactive molecules, particularly in CNS-targeted and enzyme inhibition applications. The hydrochloride salt enhances stability and solubility, facilitating handling and reaction compatibility. The compound’s rigid piperidine core and sulfonamide linkage contribute to precise molecular interactions, often employed in medicinal chemistry for lead optimization. High-purity grades ensure reproducibility in research and development, while its well-defined synthetic route supports scalable production. Suitable for controlled modifications in drug discovery pipelines.
(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride structure
1215609-88-3 structure
Product Name:(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride
CAS No:1215609-88-3
MF:C12H18ClFN2O2S
MW:308.799924373627
CID:2090837
PubChem ID:66570200
Update Time:2025-05-19

(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride
    • [1-(4-fluorophenyl)sulfonylpiperidin-4-yl]methanamine,hydrochloride
    • [1-(4-fluorophenyl)sulfonylpiperidin-4-yl]methanamine;hydrochloride
    • DB-307705
    • 1-[1-(4-FLUOROBENZENESULFONYL)PIPERIDIN-4-YL]METHANAMINE HYDROCHLORIDE
    • AKOS024464060
    • 1215609-88-3
    • CS-0442570
    • C-[1-(4-Fluoro-benzenesulfonyl)-piperidin-4-yl]-methylamine hydrochloride
    • G69995
    • (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanaminehydrochloride
    • MDL: MFCD21098936
    • Inchi: 1S/C12H17FN2O2S.ClH/c13-11-1-3-12(4-2-11)18(16,17)15-7-5-10(9-14)6-8-15;/h1-4,10H,5-9,14H2;1H
    • InChI Key: HULLBQJUIHDHFS-UHFFFAOYSA-N
    • SMILES: Cl.S(C1C=CC(=CC=1)F)(N1CCC(CN)CC1)(=O)=O

Computed Properties

  • Exact Mass: 308.0761549g/mol
  • Monoisotopic Mass: 308.0761549g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 19
  • Rotatable Bond Count: 3
  • Complexity: 353
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 71.8?2

(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride Pricemore >>

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Additional information on (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride

Comprehensive Guide to (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride (CAS No. 1215609-88-3)

(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride (CAS No. 1215609-88-3) is a specialized chemical compound with significant applications in pharmaceutical research and development. This compound, often referred to in scientific literature due to its unique structural properties, has garnered attention for its potential role in drug discovery and biochemical studies. The presence of the 4-fluorophenylsulfonyl group and the piperidin-4-yl methanamine backbone makes it a valuable intermediate in synthesizing bioactive molecules.

The compound’s molecular formula and structural features have been extensively studied to understand its reactivity and potential applications. Researchers are particularly interested in its role as a building block for designing novel therapeutic agents. The hydrochloride salt form enhances its solubility, making it suitable for various experimental protocols. With the growing demand for innovative drug candidates, (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride has become a focal point in medicinal chemistry.

One of the key areas where this compound is utilized is in the development of central nervous system (CNS) targeting drugs. The piperidine moiety is a common pharmacophore in many CNS-active compounds, and modifications with the 4-fluorophenylsulfonyl group can influence binding affinity and selectivity. Recent studies have explored its potential in addressing neurological disorders, aligning with the increasing global focus on mental health and neurodegenerative diseases.

In addition to its pharmaceutical applications, (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride is also employed in academic and industrial research. Its versatility as a synthetic intermediate allows chemists to explore new reaction pathways and develop structurally diverse compounds. The compound’s stability under various conditions makes it a reliable choice for high-throughput screening and combinatorial chemistry.

The market for specialty chemicals like (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride is expanding, driven by advancements in drug discovery and personalized medicine. As the pharmaceutical industry shifts toward targeted therapies, the demand for high-purity intermediates is expected to rise. This compound’s unique properties position it as a critical component in the synthesis of next-generation therapeutics.

From a regulatory perspective, (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride is handled under standard laboratory safety protocols. Researchers are advised to follow Good Laboratory Practices (GLP) and ensure proper storage conditions to maintain its integrity. The compound’s safety profile and handling guidelines are well-documented, making it accessible for qualified professionals.

In summary, (1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)methanamine hydrochloride (CAS No. 1215609-88-3) is a valuable chemical entity with broad applications in pharmaceutical research. Its structural features and reactivity make it a promising candidate for drug development, particularly in the CNS domain. As the scientific community continues to explore its potential, this compound is poised to play a pivotal role in advancing medicinal chemistry and therapeutic innovation.

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