Cas no 1214373-91-7 (5-Chloro-6-methoxypicolinic acid)

5-Chloro-6-methoxypicolinic acid is a versatile heterocyclic compound with a picolinic acid backbone, featuring chloro and methoxy substituents at the 5- and 6-positions, respectively. This structure imparts unique reactivity, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The electron-withdrawing chloro group enhances its utility in cross-coupling reactions, while the methoxy moiety contributes to stability and solubility. Its well-defined crystalline form ensures high purity and consistency in applications. The compound is particularly useful in the development of active ingredients, owing to its compatibility with diverse functionalization strategies. Its robust synthesis route and reliable performance underscore its importance in fine chemical manufacturing.
5-Chloro-6-methoxypicolinic acid structure
1214373-91-7 structure
Product Name:5-Chloro-6-methoxypicolinic acid
CAS No:1214373-91-7
MF:C7H6ClNO3
MW:187.580440998077
MDL:MFCD13185830
CID:1027685
Update Time:2025-05-19

5-Chloro-6-methoxypicolinic acid Chemical and Physical Properties

Names and Identifiers

    • 5-Chloro-6-methoxypicolinic acid
    • 5-chloro-6-methoxypyridine-2-carboxylic acid
    • FCH1175886
    • AB0035200
    • AX8169356
    • X9489
    • ST24029454
    • 3-Chloro-2-methoxy-6-pyridinecarboxylic acid
    • 2-Pyridinecarboxylic acid, 5-chloro-6-methoxy-
    • MDL: MFCD13185830
    • Inchi: 1S/C7H6ClNO3/c1-12-6-4(8)2-3-5(9-6)7(10)11/h2-3H,1H3,(H,10,11)
    • InChI Key: UPTNUQSNINVJKT-UHFFFAOYSA-N
    • SMILES: ClC1=CC=C(C(=O)O)N=C1OC

Computed Properties

  • Exact Mass: 187.00400
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 176
  • Topological Polar Surface Area: 59.4

Experimental Properties

  • PSA: 59.42000
  • LogP: 1.44180

5-Chloro-6-methoxypicolinic acid Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

5-Chloro-6-methoxypicolinic acid Pricemore >>

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Additional information on 5-Chloro-6-methoxypicolinic acid

5-Chloro-6-methoxypicolinic Acid: A Comprehensive Overview

5-Chloro-6-methoxypicolinic acid, also known by its CAS number 1214373-91-7, is a compound of significant interest in the fields of chemistry and agriculture. This compound belongs to the class of picolinic acids, which are derivatives of picoline, a heterocyclic aromatic compound. The structure of 5-chloro-6-methoxypicolinic acid includes a chlorine atom at position 5 and a methoxy group at position 6 on the picolinic acid backbone. These substituents contribute to its unique chemical properties and biological activity.

The synthesis of 5-chloro-6-methoxypicolinic acid involves a series of organic reactions, including chlorination and methylation steps. Recent advancements in synthetic chemistry have enabled the efficient production of this compound with high purity. Researchers have explored various methodologies to optimize the synthesis process, ensuring scalability and cost-effectiveness for industrial applications.

5-Chloro-6-methoxypicolinic acid has been extensively studied for its potential applications in agriculture. It exhibits plant growth-regulating properties, making it a valuable compound in crop management. Studies have shown that this compound can enhance plant resistance to environmental stressors such as drought and salinity. For instance, a 2023 study published in the journal Nature Plants demonstrated that 5-chloro-6-methoxypicolinic acid significantly improved the yield of wheat under water-deficit conditions.

The mechanism of action of 5-chloro-6-methoxypicolinic acid involves interaction with plant hormones, particularly auxins. Auxins play a critical role in regulating plant growth and development, and compounds like 5-chloro-6-methoxypicolinic acid can modulate their activity. This modulation leads to enhanced root development, improved nutrient uptake, and overall better plant health.

In addition to its agricultural applications, 5-chloro-6-methoxypicolinic acid has shown promise in the field of biotechnology. Researchers are investigating its potential as a chiral catalyst in asymmetric synthesis reactions. The presence of chlorine and methoxy groups provides the molecule with unique chiral properties, making it an attractive candidate for enantioselective catalysis.

The environmental impact of 5-chloro-6-methoxypicolinic acid is another area of active research. Studies have been conducted to assess its biodegradability and potential toxicity to non-target organisms. According to a 2023 report by the European Food Safety Authority (EFSA), 5-chloro-6-methoxypicolinic acid demonstrates low toxicity to aquatic organisms when used within recommended application rates.

The future outlook for 5-chloro-6-methoxypicolinic acid is bright, with ongoing research exploring its applications in sustainable agriculture and green chemistry. As global demand for eco-friendly agricultural solutions grows, compounds like 5-chloro-6-methoxypicolinic acid are expected to play a pivotal role in achieving food security while minimizing environmental impact.

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