• 1. Evolution study of photo-synthesized gold nanoparticles by spectral deconvolution model: a quantitative approach
  Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735
• 2. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 3. Evolutionary approaches in protein engineering towards biomaterial construction
  Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
• 4. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 5. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026

Introduction to 2,5-Dichloro-3-(pyridin-3-yl)pyridine (CAS No. 1214360-90-3)

2,5-Dichloro-3-(pyridin-3-yl)pyridine, with the CAS number 1214360-90-3, is a versatile compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound is characterized by its unique structure, which combines a pyridine ring with dichloro substituents and a pyridinyl group. Its chemical properties and potential biological activities make it a valuable candidate for various applications, including drug discovery and development.

The molecular formula of 2,5-Dichloro-3-(pyridin-3-yl)pyridine is C₁₀H₆Cl₂N₂, and its molecular weight is approximately 217.07 g/mol. The compound's structure features a central pyridine ring with two chlorine atoms at the 2 and 5 positions, and a pyridinyl group at the 3 position. This arrangement imparts unique chemical and physical properties to the molecule, making it an interesting subject for both academic research and industrial applications.

In recent years, there has been a growing interest in the use of 2,5-Dichloro-3-(pyridin-3-yl)pyridine as a building block in the synthesis of more complex molecules. Its reactivity and stability make it an ideal starting material for various chemical transformations. For instance, it can be used in coupling reactions to form new carbon-carbon or carbon-heteroatom bonds, which are crucial steps in the synthesis of pharmaceuticals and other bioactive compounds.

The biological activity of 2,5-Dichloro-3-(pyridin-3-yl)pyridine has also been explored in several studies. Research has shown that this compound exhibits potent inhibitory effects on certain enzymes and receptors, which are implicated in various diseases. For example, it has been reported to inhibit the activity of kinases, which are key enzymes involved in signal transduction pathways. This property makes it a potential lead compound for the development of new therapeutic agents targeting cancer and other diseases characterized by aberrant kinase activity.

Beyond its potential as a drug candidate, 2,5-Dichloro-3-(pyridin-3-yl)pyridine has also been investigated for its use in diagnostic imaging. The compound's ability to interact with specific biological targets can be harnessed to develop imaging agents that can visualize these targets in vivo. This application is particularly relevant in the field of oncology, where non-invasive methods for detecting and monitoring tumors are highly sought after.

The synthesis of 2,5-Dichloro-3-(pyridin-3-yl)pyridine has been optimized through various methods, including transition metal-catalyzed cross-coupling reactions and multistep synthetic routes. These methods have enabled researchers to produce the compound on a larger scale, facilitating its use in both laboratory settings and industrial processes. The choice of synthetic route often depends on factors such as yield, purity, and cost-effectiveness.

In addition to its chemical synthesis, the safety profile of 2,5-Dichloro-3-(pyridin-3-yl)pyridine has been evaluated in several studies. While it is generally considered safe for use in laboratory settings when proper handling protocols are followed, it is important to note that any compound should be handled with care to avoid exposure to skin or inhalation. Safety data sheets (SDS) provide detailed information on the proper handling and storage of this compound.

The future prospects for 2,5-Dichloro-3-(pyridin-3-yl)pyridine are promising. Ongoing research continues to uncover new applications and potential uses for this compound. For instance, recent studies have explored its role as a ligand in metalloenzyme inhibition and its potential as a scaffold for the development of novel antibiotics. These findings highlight the versatility and importance of this compound in advancing our understanding of biological systems and developing new therapeutic strategies.

In conclusion, 2,5-Dichloro-3-(pyridin-3-yl)pyridine (CAS No. 1214360-90-3) is a multifaceted compound with significant potential in various areas of research and development. Its unique chemical structure and biological properties make it an attractive candidate for further investigation and application in medicinal chemistry, pharmaceuticals, and diagnostic imaging. As research progresses, it is likely that new insights into the utility of this compound will continue to emerge.

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