• 1. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
• 2. An air-stable organometallic polymer containing titanafluorene moieties obtained by the Sonogashira–Hagihara cross-coupling polycondensation?
  Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
• 3. An all-solid-state imprinted polymer-based potentiometric sensor for determination of bisphenol S?
  Rongning Liang,Tanji Yin,Ruiqing Yao,Wei Qin RSC Adv., 2016,6, 73308-73312
• 4. Alumina grafted SBA-15 sustainable bifunctional catalysts for direct cross-coupling of benzylic alcohols to diarylmethanes?
  Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
• 5. An artificial CO-releasing metalloprotein built by histidine-selective metallation?
  Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridinecarboxylic acids and derivatives Pyridinecarboxylic acids

Ethyl 5-Bromo-2-Chloronicotinate: A Comprehensive Overview

Ethyl 5-bromo-2-chloronicotinate, with CAS No. 1214332-67-8, is a chemical compound that has garnered significant attention in the fields of organic chemistry and material science. This compound is a derivative of nicotinic acid, a key component in various biological and industrial applications. The ethyl 5-bromo-2-chloronicotinate structure incorporates a bromine atom at the 5-position and a chlorine atom at the 2-position of the nicotinate ring, making it a unique member of the substituted nicotinates family.

The synthesis of ethyl 5-bromo-2-chloronicotinate involves a series of carefully controlled reactions, including substitution and esterification processes. Recent advancements in synthetic methodologies have enabled researchers to optimize the production of this compound, ensuring higher yields and improved purity. The compound's structure has been extensively studied using techniques such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy, providing insights into its molecular geometry and electronic properties.

Ethyl 5-bromo-2-chloronicotinate exhibits interesting physical and chemical properties that make it suitable for various applications. Its solubility in organic solvents, coupled with its thermal stability, makes it an ideal candidate for use in pharmaceutical formulations and agrochemicals. Moreover, the compound's ability to act as an intermediate in the synthesis of more complex molecules has been highlighted in recent studies.

Recent research has focused on the potential of ethyl 5-bromo-2-chloronicotinate in drug discovery. Scientists have explored its role as a lead compound in the development of new therapeutic agents targeting specific biological pathways. For instance, studies have shown that this compound may exhibit inhibitory activity against certain enzymes involved in metabolic disorders, opening new avenues for its application in pharmacology.

In addition to its pharmacological applications, ethyl 5-bromo-2-chloronicotinate has also been investigated for its role in material science. Researchers have examined its potential as a precursor for advanced materials such as polymers and nanomaterials. The compound's ability to form stable complexes with metal ions has been particularly promising, suggesting its use in catalysis and sensing technologies.

The environmental impact of ethyl 5-bromo-2-chloronicotinate has also been a topic of recent interest. Studies have assessed its biodegradability and toxicity under various conditions, providing valuable data for regulatory purposes. These findings underscore the importance of sustainable practices in the production and disposal of such compounds.

In conclusion, ethyl 5-bromo-2-chloronicotinate (CAS No. 1214332-67-8) is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical structure, coupled with advancements in synthetic methods and application studies, positions it as an important molecule for future research and development.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)