• 1. An approach to biodegradable star polymeric architectures using disulfide coupling?
  Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
• 2. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381
• 3. Acetylcholinesterase amperometric detection system based on a cobalt(II) tetraphenylporphyrin-modified electrode
  Analyst, 1996,121, 1123-1126
• 4. An algal process treatment combined with the Fenton reaction for high concentrations of amoxicillin and cefradine
  Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
• 5. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383

2-Fluoro-3-Iodo-4-Methylpyridine: A Comprehensive Overview

2-Fluoro-3-Iodo-4-Methylpyridine (CAS No. 1214323-08-6) is a heterocyclic aromatic compound that has garnered significant attention in the fields of organic synthesis, medicinal chemistry, and materials science. This compound belongs to the pyridine family, a class of six-membered aromatic rings with one nitrogen atom. The presence of fluorine, iodine, and methyl substituents at specific positions on the pyridine ring imparts unique electronic and structural properties, making it a valuable building block for various applications.

The molecular formula of 2-fluoro-3-iodo-4-methylpyridine is C₆H₅FIN, with a molecular weight of approximately 296.9 g/mol. Its structure consists of a pyridine ring where the fluorine atom is located at position 2, the iodine atom at position 3, and the methyl group at position 4. This substitution pattern creates a molecule with distinct electronic characteristics due to the electron-withdrawing effects of fluorine and iodine, as well as the electron-donating effect of the methyl group. These properties make 2-fluoro-3-iodo-4-methylpyridine highly versatile in chemical reactions and applications.

Recent studies have highlighted the role of 2-fluoro-3-iodo-4-methylpyridine in drug discovery and development. Its ability to act as an intermediate in the synthesis of bioactive compounds has been extensively explored. For instance, researchers have utilized this compound to synthesize potential anticancer agents by incorporating it into larger molecular frameworks. The iodine substituent in particular facilitates nucleophilic aromatic substitution reactions, enabling the construction of complex molecules with desired pharmacological properties.

In addition to its role in medicinal chemistry, 2-fluoro-3-iodo-4-methylpyridine has found applications in materials science. Its unique electronic properties make it a promising candidate for use in organic electronics, such as in the development of light-emitting diodes (LEDs) and field-effect transistors (FETs). Recent advancements in this area have demonstrated that derivatives of this compound can exhibit enhanced charge transport properties, making them suitable for next-generation electronic devices.

The synthesis of 2-fluoro-3-i

• 1803766-18-8(2-Fluoro-5-iodo-4-phenylpyridine)
• 1804433-30-4(4-Ethyl-2-fluoro-5-iodopyridine)
• 1807012-98-1(4-Aminomethyl-2-fluoro-3-iodopyridine)
• 153034-78-7(2-Fluoro-3-iodo-5-methylpyridine)
• 1805046-08-5(4-(Difluoromethyl)-3,5-diiodo-2-fluoropyridine)
• 1803878-75-2(2-Fluoro-3-iodo-4-phenylpyridine)
• 1804887-96-4(4-Chloromethyl-2-fluoro-3-iodopyridine)
• 1184913-75-4(2-Fluoro-5-iodo-4-methylpyridine)
• 1227595-15-4(2-Fluoro-3-iodo-4-(trifluoromethyl)pyridine)
• 1805505-90-1(4-Aminomethyl-2-fluoro-5-iodopyridine)