Cas no 1208313-37-4 (3-Chloro-5-fluoro-4-methylphenylboronic acid)

3-Chloro-5-fluoro-4-methylphenylboronic acid is a boronic acid derivative widely used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of complex biaryl structures. Its halogen-substituted aromatic ring enhances reactivity and selectivity in palladium-catalyzed transformations, making it valuable for pharmaceutical and agrochemical applications. The presence of both chloro and fluoro substituents, along with the methyl group, offers steric and electronic modulation for tailored coupling efficiency. This compound exhibits good stability under standard handling conditions and is compatible with a range of solvents and reagents. Its high purity and reliable performance make it a preferred choice for research and industrial-scale synthesis.
3-Chloro-5-fluoro-4-methylphenylboronic acid structure
1208313-37-4 structure
Product Name:3-Chloro-5-fluoro-4-methylphenylboronic acid
CAS No:1208313-37-4
MF:C7H7BClFO2
MW:188.391684770584
CID:5003565
Update Time:2025-06-07

3-Chloro-5-fluoro-4-methylphenylboronic acid Chemical and Physical Properties

Names and Identifiers

    • 3-Chloro-5-fluoro-4-methylphenylboronic acid
    • Inchi: 1S/C7H7BClFO2/c1-4-6(9)2-5(8(11)12)3-7(4)10/h2-3,11-12H,1H3
    • InChI Key: HCIXNKOVNHJHPS-UHFFFAOYSA-N
    • SMILES: ClC1C=C(B(O)O)C=C(C=1C)F

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 158
  • Topological Polar Surface Area: 40.5

3-Chloro-5-fluoro-4-methylphenylboronic acid Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A010011422-250mg
3-Chloro-5-fluoro-4-methylphenylboronic acid
1208313-37-4 97%
250mg
$480.00 2023-09-04
Alichem
A010011422-500mg
3-Chloro-5-fluoro-4-methylphenylboronic acid
1208313-37-4 97%
500mg
$790.55 2023-09-04
Alichem
A010011422-1g
3-Chloro-5-fluoro-4-methylphenylboronic acid
1208313-37-4 97%
1g
$1475.10 2023-09-04
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