• 1. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 2. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 3. Emulsion technologies for multicellular tumour spheroid radiation assays?
  Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
• 4. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 5. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341

• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Phenylpropanoic acids Phenylpropanoic acids
• Solvents and Organic Chemicals Organic Compounds Phenylpropanoids and polyketides Phenylpropanoic acids

3-(4-tert-butylphenyl)propanoic Acid (CAS 1208-64-6): Properties, Applications, and Market Insights

3-(4-tert-butylphenyl)propanoic acid (CAS 1208-64-6) is a specialized organic compound that has garnered significant attention in the chemical and pharmaceutical industries. This aromatic carboxylic acid, characterized by its tert-butylphenyl group, is widely utilized in various applications, ranging from pharmaceutical intermediates to cosmetic formulations. Its unique chemical structure and properties make it a valuable component in synthetic chemistry and industrial processes.

The molecular formula of 3-(4-tert-butylphenyl)propanoic acid is C₁₃H₁₈O₂, with a molecular weight of 206.28 g/mol. The presence of the tert-butyl group enhances its stability and solubility in organic solvents, making it an ideal candidate for reactions requiring controlled conditions. Researchers and manufacturers often seek this compound for its role in producing high-performance polymers, UV stabilizers, and fragrance ingredients.

One of the most notable applications of 3-(4-tert-butylphenyl)propanoic acid is in the pharmaceutical sector, where it serves as a key intermediate in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs). Its ability to modulate inflammatory pathways has sparked interest in drug development, particularly for conditions like arthritis and chronic pain. Additionally, its derivatives are explored for their potential in antioxidant formulations, aligning with the growing consumer demand for health and wellness products.

In the cosmetic industry, 3-(4-tert-butylphenyl)propanoic acid is valued for its role in stabilizing formulations and enhancing product longevity. With the rise of clean beauty trends, this compound is increasingly studied for its compatibility with natural ingredients and its ability to improve the efficacy of skincare products. Its mild yet effective properties make it suitable for sensitive skin applications, addressing a common concern among modern consumers.

From a market perspective, the demand for 3-(4-tert-butylphenyl)propanoic acid is driven by advancements in green chemistry and sustainable manufacturing. Companies are investing in eco-friendly synthesis methods to reduce environmental impact, a trend that resonates with global sustainability goals. Furthermore, the compound's versatility in specialty chemicals ensures its relevance in niche markets, including agrochemicals and advanced materials.

Researchers frequently inquire about the synthesis pathway of 3-(4-tert-butylphenyl)propanoic acid, as optimizing its production remains a topic of interest. Common methods include the Friedel-Crafts acylation of tert-butylbenzene, followed by oxidation steps to yield the final product. Innovations in catalytic processes have improved yields and reduced waste, addressing the industry's push toward cost-effective and sustainable chemistry.

Safety and handling of 3-(4-tert-butylphenyl)propanoic acid are also critical considerations. While it is not classified as a hazardous substance, proper storage conditions—such as avoiding prolonged exposure to light and moisture—are recommended to maintain its stability. Regulatory compliance, particularly in the pharmaceutical and cosmetic sectors, ensures its safe integration into end products.

In conclusion, 3-(4-tert-butylphenyl)propanoic acid (CAS 1208-64-6) stands out as a multifaceted compound with broad industrial relevance. Its applications in drug development, cosmetic science, and material innovation highlight its importance in modern chemistry. As industries continue to prioritize sustainability and efficiency, this compound is poised to play a pivotal role in shaping future advancements.

• 90020-73-8(Hexanedioic acid, 3,4-dimethyl-3,4-diphenyl-)
• 24475-36-3(4-(4-tert-butylphenyl)butanoic acid)
• 42288-01-7(3-(3,5-di-tert-butylphenyl)propanoic acid)
• 1010-48-6(3-Methyl-3-phenylbutanoic acid)
• 26118-58-1(Benzenepropanoic acid, 4-(1,1-dimethylpropyl)-)
• 15954-43-5(Benzenepropanoic acid,4-(1,1-dimethylethyl)-b-methyl-)
• 42288-08-4(3-Methyl-3-(4-methylphenyl)butanoic acid)
• 142260-26-2(Benzeneheptanoic acid, 4-[[4-(1,1-dimethylethyl)phenyl]methyl]-)
• 4160-92-3(3-methyl-3-phenylpentanedioic Acid)
• 58420-21-6(3-[4-(propan-2-yl)phenyl]propanoic acid)