Cas no 1206250-53-4 (4-Bromo-2-chloro-6-methylpyridine)

4-Bromo-2-chloro-6-methylpyridine is a halogenated pyridine derivative with a molecular formula of C6H5BrClN. This compound serves as a versatile intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. Its bromo and chloro substituents enhance reactivity, facilitating selective cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. The methyl group at the 6-position offers additional steric and electronic modulation, making it valuable for constructing complex heterocyclic frameworks. The compound exhibits high purity and stability under standard conditions, ensuring reliable performance in synthetic workflows. Its well-defined structure and functional group compatibility make it a preferred choice for researchers developing novel bioactive molecules or advanced materials.
4-Bromo-2-chloro-6-methylpyridine structure
1206250-53-4 structure
Product Name:4-Bromo-2-chloro-6-methylpyridine
CAS No:1206250-53-4
MF:C6H5BrClN
MW:206.467599630356
MDL:MFCD14582031
CID:823542
PubChem ID:53429237
Update Time:2025-10-28

4-Bromo-2-chloro-6-methylpyridine Chemical and Physical Properties

Names and Identifiers

    • 4-Bromo-2-chloro-6-methylpyridine
    • 4-Bromo-6-chloropicoline
    • MFCD14582031
    • AKOS015910054
    • DTXSID00700098
    • SY096968
    • DB-367418
    • EN300-314378
    • CS-0051001
    • 1206250-53-4
    • SB21181
    • AS-49415
    • I10130
    • SCHEMBL15956513
    • MDL: MFCD14582031
    • Inchi: 1S/C6H5BrClN/c1-4-2-5(7)3-6(8)9-4/h2-3H,1H3
    • InChI Key: VZKVJDPXLSTENW-UHFFFAOYSA-N
    • SMILES: BrC1C=C(N=C(C)C=1)Cl

Computed Properties

  • Exact Mass: 204.92900
  • Monoisotopic Mass: 204.929
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 0
  • Complexity: 99.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 12.9A^2
  • XLogP3: 2.9

Experimental Properties

  • Density: 1.624
  • Boiling Point: 238 oC
  • Flash Point: 98 oC
  • PSA: 12.89000
  • LogP: 2.80590

4-Bromo-2-chloro-6-methylpyridine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-Bromo-2-chloro-6-methylpyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A023022807-1g
4-Bromo-2-chloro-6-methylpyridine
1206250-53-4 97%
1g
$484.84 2023-09-04
TRC
B684318-25mg
4-Bromo-6-chloropicoline
1206250-53-4
25mg
$ 92.00 2023-04-18
TRC
B684318-50mg
4-Bromo-6-chloropicoline
1206250-53-4
50mg
$ 150.00 2023-04-18
TRC
B684318-100mg
4-Bromo-6-chloropicoline
1206250-53-4
100mg
$ 224.00 2023-04-18
TRC
B684318-250mg
4-Bromo-6-chloropicoline
1206250-53-4
250mg
$ 397.00 2023-04-18
Chemenu
CM175095-1g
4-Bromo-2-chloro-6-methylpyridine
1206250-53-4 95%
1g
$400 2021-08-05
CHENG DOU FEI BO YI YAO Technology Co., Ltd.
FB00172-5g
4-bromo-2-chloro-6-methylpyridine
1206250-53-4 95%
5g
$1275 2023-09-07
Fluorochem
210619-250mg
4-Bromo-2-chloro-6-methylpyridine
1206250-53-4 95%
250mg
£140.00 2022-02-28
Fluorochem
210619-1g
4-Bromo-2-chloro-6-methylpyridine
1206250-53-4 95%
1g
£343.00 2022-02-28
Fluorochem
210619-5g
4-Bromo-2-chloro-6-methylpyridine
1206250-53-4 95%
5g
£982.00 2022-02-28

Additional information on 4-Bromo-2-chloro-6-methylpyridine

4-Bromo-2-chloro-6-methylpyridine: A Comprehensive Overview

4-Bromo-2-chloro-6-methylpyridine, with the CAS number 1206250-53-4, is a heterocyclic aromatic compound that has garnered significant attention in the fields of organic chemistry and materials science. This compound, belonging to the pyridine family, is characterized by its unique substitution pattern, featuring bromine, chlorine, and methyl groups at specific positions on the pyridine ring. Its structure not only imparts distinct electronic properties but also renders it highly versatile for various applications.

The synthesis of 4-Bromo-2-chloro-6-methylpyridine typically involves multi-step processes that require precise control over reaction conditions. Recent advancements in catalytic methods have enabled more efficient and selective syntheses, reducing the environmental footprint associated with traditional manufacturing techniques. Researchers have also explored alternative routes using microwave-assisted synthesis and continuous-flow reactors, which promise higher yields and shorter reaction times.

In terms of chemical properties, 4-Bromo-2-chloro-6-methylpyridine exhibits a high degree of stability under standard conditions. Its electronic configuration, influenced by the electron-withdrawing bromine and chlorine atoms and the electron-donating methyl group, makes it an excellent candidate for various reactions. For instance, it has been employed as a precursor in the synthesis of bioactive molecules, where its reactivity can be fine-tuned to achieve desired transformations.

The application of 4-Bromo-2-chloro-6-methylpyridine extends beyond traditional organic synthesis. Recent studies have highlighted its potential in the development of advanced materials, such as coordination polymers and metal-organic frameworks (MOFs). These materials leverage the compound's ability to act as a ligand, facilitating the formation of highly ordered structures with tunable pore sizes and functionalities.

In the realm of pharmacology, 4-Bromo-2-chloro-6-methylpyridine has shown promise as a building block for drug discovery. Its substitution pattern allows for easy modification to target specific biological pathways. For example, derivatives of this compound have been investigated for their anti-inflammatory and anticancer properties. Collaborative efforts between chemists and biologists have further elucidated its mechanism of action, paving the way for novel therapeutic strategies.

The environmental impact of synthesizing and utilizing 4-Bromo-2-chloro-6-methylpyridine is another area of active research. Scientists are exploring green chemistry approaches to minimize waste generation and reduce energy consumption during production. Additionally, studies on its biodegradation pathways are underway to ensure that its use aligns with sustainable practices.

In conclusion, 4-Bromo-2-chloro-6-methylpyridine, with its unique chemical properties and diverse applications, remains a focal point in contemporary research. As advancements in synthetic methodologies and material science continue to unfold, this compound is poised to play an even more significant role in shaping future innovations across multiple disciplines.

Recommended suppliers
Xiamen PinR Bio-tech Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Xiamen PinR Bio-tech Co., Ltd.
Zouping Mingyuan Import and Export Trading Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zouping Mingyuan Import and Export Trading Co., Ltd
Shanghai Jinhuan Chemical CO., LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shanghai Jinhuan Chemical CO., LTD.
煙臺(tái)朗裕新材料科技有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hangzhou TSurgeX Pharmaceutical Technology Co., Ltd.