• 1. An insight into the origin of room-temperature ferromagnetism in SnO2 and Mn-doped SnO2 quantum dots: an experimental and DFT approach?
  Dhamodaran Manikandan,S. Amirthapandian,I. S. Zhidkov,A. I. Kukharenko,S. O. Cholakh,Ramaswamy Murugan Phys. Chem. Chem. Phys., 2018,20, 6500-6514
• 2. An anti-ultrasonic-stripping effect in confined micro/nanoscale cavities and its applications for efficient multiscale metallic patterning?
  Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
• 3. An integrated process of CO2 capture and in situ hydrogenation to formate using a tunable ethoxyl-functionalized amidine and Rh/bisphosphine system?
  Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
• 4. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187
• 5. An atomistic mechanism for the degradation of perovskite solar cells by trapped charge?
  Eunhak Lim,Jiyoung Heo,Seong Keun Kim Nanoscale, 2019,11, 11369-11378

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Pyrazoles

Professional Introduction to Compound with CAS No 1201935-87-6 and Product Name: 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol

The compound with the CAS number 1201935-87-6 and the product name 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol represents a significant area of interest in the field of chemical biology and pharmaceutical research. This compound, featuring a pyrazole core structure, has garnered attention due to its potential applications in drug discovery and development. The pyrazole moiety is a heterocyclic aromatic compound that is widely recognized for its versatility in medicinal chemistry, often serving as a key structural component in various bioactive molecules.

Pyrazole derivatives have been extensively studied for their pharmacological properties, including antimicrobial, anti-inflammatory, and anticancer activities. The specific substitution pattern in 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol, particularly the presence of an amino group at the 4-position and a methyl group at the 3-position, contributes to its unique chemical and biological profile. These substituents not only influence the compound's solubility and stability but also play a crucial role in its interactions with biological targets.

Recent advancements in computational chemistry and molecular modeling have enabled researchers to predict the binding affinities and mechanisms of action of such compounds with remarkable accuracy. The structural features of 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol make it a promising candidate for further investigation as a scaffold for developing novel therapeutic agents. For instance, studies have shown that pyrazole derivatives can modulate enzyme activity by binding to specific residues within the active site, thereby inhibiting or activating enzymatic pathways relevant to various diseases.

In the context of drug discovery, the compound's ability to interact with biological targets is of paramount importance. The amino group at the 4-position of the pyrazole ring can form hydrogen bonds with polar residues in proteins, enhancing binding affinity. Additionally, the methyl group at the 3-position may contribute to hydrophobic interactions, further stabilizing the compound-protein complex. These interactions are critical for designing molecules that exhibit high selectivity and efficacy.

One of the most exciting aspects of 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol is its potential in addressing unmet medical needs. Current research indicates that this compound may have applications in treating inflammatory disorders by inhibiting key inflammatory pathways. For example, studies have demonstrated that pyrazole derivatives can suppress the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). By modulating these pathways, the compound could offer a novel approach to managing chronic inflammatory conditions.

The ethanol moiety in the name 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol also contributes to the compound's overall properties. The hydroxyl group can participate in hydrogen bonding, both as a donor and an acceptor, which is beneficial for binding to biological targets. Moreover, the ethanol group can influence solubility characteristics, making the compound more suitable for formulation into various delivery systems.

Recent clinical trials have provided valuable insights into the pharmacokinetic and pharmacodynamic properties of pyrazole-based compounds. These studies have highlighted the importance of optimizing structural features to enhance bioavailability and reduce toxicity. The findings suggest that compounds like 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol have the potential to be developed into safe and effective therapeutic agents if further refined through structure-activity relationship (SAR) studies.

In conclusion, 2-(4-Amino-3-methyl-pyrazol-1-yl)-ethanol represents a promising candidate for drug development due to its unique structural features and potential biological activities. The combination of computational modeling, experimental validation, and clinical research will be essential in fully realizing its therapeutic potential. As our understanding of disease mechanisms continues to evolve, compounds like this will play an increasingly important role in addressing complex medical challenges.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)