Cas no 120-47-8 (Ethylparaben)
Ethylparaben Chemical and Physical Properties
Names and Identifiers
-
- Ethyl 4-hydroxybenzoate
- 4-(ethoxycarbonyl)phenol
- 4-HYDROXYBENZOIC ACID ETHYL ESTER
- ethyl butex
- ETHYLPARABEN
- ETHYL PARASEPT
- ETHYL P-HYDROXYBENZOATE
- p-hydroxybenzoate ethyl ester
- P-HYDROXYBENZOIC ACID ETHYL ESTER
- RARECHEM AL BI 0098
- 4-Carbethoxyphenol
- 4-hydroxy-benzoicaciethylester
- Aseptin a
- Aseptine a
- Aseptoform E
- Benzoic acid, 4-hydroxy-, ethyl ester
- Benzoic acid, p-hydroxy-, ethyl ester
- Ethyl 4-Hydroxybenzoate [for Biochemical Research]
- ETHYL-4-HYDROXYBENZOATE(SG)
- Ethyl-p-hydroxybenzoate
- 4-hydrodxybenzoic acid ethylester
- 4-hydroxybenzoic ethyl ester
- Easeptol
- ethyl para-hydroxybenzoate
- Ethyl parahydroxybenzoate
- Keloform
- Mycocten
- napagina
- nipagina
- nipazina
- para-hydroxybenzoic acid ethyl ester
- Sobrol A
- solbrola
- Ethyl Hydroxybenzoate, Nipagin A, Ethylparaban
- [ "Ethyl 4-hydroxybenzoate" ]
- Ethyl
- Of ethyl
- Solbro A
- Ethyl paraben
- Tegosept E
- Solbrol A
- Nipazin A
- Nipagin A
- Napagin A
- p-Carbethoxyphenol
- Mekkings E
- Bonomold OE
- Ethyl p-oxybenzoate
- Carbethoxyphenol
- Ethyl-4-hydroxybenzoate
- p-
- Ethyl Hydroxybenzoate
- 4-Hydroxybenzoic Acid Ethyl Ester,99%
- E214
- p-Oxybenzoesaeureaethylester
- E-214
- EPA Pesticide Chemical Code 061202
- 4-hydroxy benzoic acid ethyl ester
- Ethyl 4-hydroxybenzoate, SAJ first grade, >=99.0%
- NCGC00160654-04
- ETHYL ESTER OF P-HYDROXYBENZOIC ACID
- 4-Hydroxybenzoic acid, ethyl ester
- p-Hydroxybenzoic acid, ethyl ester
- InChI=1/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H
- HY-B0934
- AC-34532
- SBI-0206674.P002
- Tox21_300335
- ETHYLPARABEN [II]
- NCGC00160654-01
- NSC-8510
- METHYL PARAHYDROXYBENZOATE IMPURITY B [EP IMPURITY]
- EINECS 204-399-4
- CCG-213682
- NCGC00160654-02
- ETHYL PARAHYDROXYBENZOATE [EP MONOGRAPH]
- NSC-23514
- ETHYLPARABEN [USP-RS]
- W-108475
- NSC755851
- UNII-14255EXE39
- p-Oxybenzoesaeureaethylester [German]
- ETHYL HYDROXYBENZOATE [MART.]
- D01647
- Caswell No. 447
- CHEMBL15841
- Ethyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard
- SCHEMBL28368
- Ethylparaben (NF)
- E4B
- Ethyl 4-Hydroxybenzoate,(S)
- ETHYL HYDROXYBENZOATE [WHO-DD]
- Tox21_111961
- SR-05000001552-1
- Ethyl 4-hydroxyl-benzoate
- Ethyl chemosept
- Ethylis hydroxybenzoas
- Ethyl 4-hydroxybenzoate, ReagentPlus(R), 99%
- HSDB 938
- Ethylparaben [NF]
- DTXCID002528
- PROPYL HYDROXYBENZOATE IMPURITY C [EP IMPURITY]
- AKOS000120512
- BIDD:ER0023
- Ethyl parahydroxybenzoate (TN)
- Ethyl 4-hydroxybenzoate, Vetec(TM) reagent grade, 99%
- Z53833636
- Ethylester kyseliny p-hydroxybenzoove
- Ethyl 4-hydroxy-benzoate
- HMS2091E17
- NCI60_041866
- 4-hydroxybenzoic acid-ethyl ester
- ETHYLPARABEN [MI]
- BBL012166
- 4-Hydroxybenzoic acid-ethyl ester 1000 microg/mL in Acetonitrile
- 4-Hydroxy-benzoic acid ethyl ester
- NSC 23514
- Ester etylowykwasu p-hydroksybenzoesowego [Polish]
- p-Hydroxybenzoic ethyl ester
- MFCD00002353
- ETHYLIS HYDROXYBENZOAS [WHO-IP LATIN]
- EC 204-399-4
- E0884
- ethyl-paraben
- AB00375765_03
- ETHYL PARAHYDROXYBENZOATE [JAN]
- H0211
- s4525
- EN300-16106
- NCGC00160654-06
- Ins no.214
- F0728-0009
- NSC23514
- Ins-214
- Pharmakon1600-01400151
- 9001-05-2
- CHEBI:31575
- AC-11586
- CS-4403
- WLN: QR DVO2
- BRD-K02464583-001-02-2
- SR-05000001552
- 4-10-00-00367 (Beilstein Handbook Reference)
- W18471
- Ethyl parahydroxybenzoate (JP17)
- Q229976
- NCGC00254462-01
- Ethylparaben, Pharmaceutical Secondary Standard; Certified Reference Material
- AS-11988
- ETHYLPARABEN [HSDB]
- NCGC00160654-03
- Ethyl parahydroxybenzoate e214
- BRD-K02464583-001-01-4
- BDBM50428380
- Ester etylowykwasu p-hydroksybenzoesowego
- Parahydroxybenzoic acid ethyl ester
- NSC-755851
- Ethylparaben, INN, USAN
- STK070911
- NSC8510
- DB13628
- NS00008316
- DTXSID9022528
- bmse010255
- 14255EXE39
- Ethylester kyseliny p-hydroxybenzoove [Czech]
- CAS-120-47-8
- BRN 1101972
- 120-47-8
- AI3-30960
- Nipagina A
- DA-73229
- Ethylparaben, United States Pharmacopeia (USP) Reference Standard
- ETHYL HYDROXYBENZOATE [WHO-IP]
- ETHYL PARAHYDROXYBENZOATE [EP IMPURITY]
- Tox21_111961_1
- ethyl 4-hydroxybenzenecarboxylate
- Ethylparaben, certified reference material, TraceCERT(R)
- HY-B0934R
- AE-646/31213037
- FE23063
- Ethylparaben (Standard)
- 4-Hydroxybenzoic acid ethyl ester;4-(Ethoxycarbonyl)phenol
- Ethylparaben
-
- MDL： MFCD00002353
- Inchi： 1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
- InChI Key： NUVBSKCKDOMJSU-UHFFFAOYSA-N
- SMILES： CCOC(C1C=CC(O)=CC=1)=O
- BRN： 1101972
Computed Properties
- Exact Mass: 166.06300
- Monoisotopic Mass: 166.062994177 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 3
- Complexity: 148
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: 2.5
- Topological Polar Surface Area: 46.5
- Molecular Weight: 166.17
Experimental Properties
- Color/Form: Powder
- Density: 1.1708 (rough estimate)
- Melting Point: 114-117?°C (lit.)
- Boiling Point: 297-298?°C(lit.)
- Flash Point: 297-298°C
- Refractive Index: 1.5286 (estimate)
- Solubility: 0.00 M
- Water Partition Coefficient: Slightly soluble in water.
- Stability/Shelf Life: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
- PSA: 46.53000
- LogP: 1.56890
- Odor: Odorless
- Sensitiveness: Sensitive to light
- Solubility: Soluble in water, the solubility is 0.070% (20 ℃) and 0.075% (25 ℃). It is stable to light and heat and has no hygroscopicity. Slightly soluble in water. Soluble in ethanol and propylene glycol.
- Merck: 3837
- Vapor Pressure: 9.29X10-5 mm Hg at 25 °C (est)
Ethylparaben Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315,H319,H335
- Warning Statement： P261,P305+P351+P338
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：1
- Hazard Category Code： R36/37/38: irritating to eyes, respiratory tract and skin
- Safety Instruction： S26-S36-S24/25
- RTECS：DH2190000
-
Hazardous Material Identification：
- Risk Phrases：R36/37/38
- Safety Term：S24/25
- TSCA：Yes
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
Ethylparaben Customs Data
- HS CODE：2918290000
- Customs Data：
China Customs Code:
2918290000Overview:
2918290000 Other carboxylic acids and anhydrides containing phenolic groups but not other oxy groups\Acyl halide\Peroxides and peroxyacids and their derivatives.Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods).VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Regulatory conditions:
A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goodsInspection and quarantine category:
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported foodSummary:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%
Ethylparaben Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-B0934-10mM*1mLinDMSO |
Ethylparaben |
120-47-8 | 98.23% | 10mM*1mLinDMSO |
￥550 | 2022-05-18 | |
| MedChemExpress | HY-B0934-100mg |
Ethylparaben |
120-47-8 | 100mg |
￥120 | 2025-04-16 | ||
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105144-100mg |
Ethylparaben |
120-47-8 | ,99.7% | 100mg |
￥205.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105144-1g |
Ethylparaben |
120-47-8 | ,99.7% | 1g |
￥510.90 | 2023-09-03 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 1008875000 |
Ethylparaben |
120-47-8 | EMPROVE | 5KG |
8964.29 | 2021-05-21 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105141-500g |
Ethylparaben |
120-47-8 | CP,99.0% | 500g |
￥83.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105141-100g |
Ethylparaben |
120-47-8 | CP,99.0% | 100g |
￥30.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105142-500g |
Ethylparaben |
120-47-8 | AR,99% | 500g |
￥125.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105142-5kg |
Ethylparaben |
120-47-8 | AR,99% | 5kg |
￥932.90 | 2023-09-03 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | E105142-100g |
Ethylparaben |
120-47-8 | AR,99% | 100g |
￥39.90 | 2023-09-03 |
Ethylparaben Suppliers
Audited Supplier
Audited Supplier
Audited Supplier
Ethylparaben Related Literature
-
Zhijun Zhang,Xi Li,Chenggang Wang,Chaocan Zhang,Peng Liu,Tingting Fang,Yan Xiong,Wenjing Xu Dalton Trans. 2012 41 1252
-
P. Baburajan,R. Senthilkumaran,Kuppanagounder P. Elango New J. Chem. 2013 37 3050
-
Nan Zhao,Xiuxiu Wang,Liru Yao,Huixuan Yan,Ban Qin,Chensha Li,Jianqi Zhang Soft Matter 2022 18 1264
-
4. Chemistry of fruit flies: composition of the male rectal gland secretions of some species of South-East Asian Dacinae. Re-examination of Dacus cucurbitae(melon fly)Michael V. Perkins,William Kitching,Richard A. I. Drew,Christopher J. Moore,Wilfried A. K?nig J. Chem. Soc. Perkin Trans. 1 1990 1111
-
Jian Liu,Lulu Xu,Chaobin He,Xuehong Lu,FuKe Wang Polym. Chem. 2021 12 5251
Related Categories
- Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives p-Hydroxybenzoic acid alkyl esters
- Pesticide Chemicals Pesticides Pesticides
- Pesticide Chemicals Pesticide Active Ingredients Standard Substances
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Reference Substances
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients Standard Substances
- Solvents and Organic Chemicals Organic Compounds Acids/Esters
- Solvents and Organic Chemicals Organic Compounds Alcohol/Ether
- Solvents and Organic Chemicals Organic Compounds Hydrocarbons
- Pharmaceutical and Biochemical Products Pharmaceutical Active Ingredients
Additional information on Ethylparaben
Ethylparaben (CAS No. 120-47-8): A Comprehensive Guide to Properties, Applications, and Safety
Ethylparaben (CAS No. 120-47-8), also known as ethyl p-hydroxybenzoate, is a widely used paraben ester with significant applications in cosmetics, pharmaceuticals, and food preservation. As consumer awareness grows regarding preservative safety and clean beauty trends, understanding this compound's role becomes increasingly important. This article explores its chemical properties, industrial applications, and addresses common questions about its safety profile.
Chemically, ethylparaben appears as a white crystalline powder with the molecular formula C9H10O3. It exhibits excellent antimicrobial properties, particularly against fungi and gram-positive bacteria, making it valuable for product preservation. Its solubility characteristics (slightly soluble in water, more soluble in alcohol and ether) contribute to its formulation flexibility. Recent studies comparing paraben alternatives continue to highlight its effectiveness at low concentrations (typically 0.1-0.3% in formulations).
In the cosmetics industry, ethylparaben serves as a preservative booster in creams, lotions, and makeup products. Its ability to extend shelf-life while maintaining formulation stability makes it particularly valuable in water-based products. Current beauty industry trends show increasing demand for multifunctional preservatives that combine efficacy with mildness, positioning ethylparaben as a balanced option among paraben derivatives.
The pharmaceutical applications of CAS 120-47-8 include its use in topical medications and some oral suspensions. Its preservative action helps maintain sterility in multi-dose preparations. Recent formulation research explores its synergy with other antimicrobial agents to create broader-spectrum protection systems. Regulatory agencies worldwide, including the FDA and EMA, continue to approve its use within established concentration limits.
Food-grade ethylparaben finds application as a food preservative (E214 in the EU) in certain processed foods and beverages. Its use aligns with the growing need for natural-like preservatives in the clean label movement. While consumer preferences shift toward preservative-free products, food scientists note that certain applications still require reliable microbial protection that compounds like ethylparaben provide.
Regarding safety considerations, numerous studies have evaluated ethylparaben toxicity. Current scientific consensus maintains that it's safe at approved concentrations, though research continues into its metabolic pathways and environmental impact. The compound's estrogenic activity, while significantly weaker than natural estrogens, remains a topic of ongoing study and discussion in cosmetic science circles.
The global market for ethylparaben reflects evolving regulatory landscapes and consumer preferences. Manufacturers are developing paraben blends and alternative systems to address specific market demands. Quality specifications for pharmaceutical-grade ethylparaben typically require ≥99% purity, with strict controls on impurity profiles and heavy metal content.
Storage and handling of ethylparaben powder require standard laboratory precautions. It should be kept in airtight containers away from moisture and strong oxidizers. While not classified as hazardous under normal conditions, proper personal protective equipment (gloves, goggles) is recommended during handling to prevent eye irritation or respiratory discomfort from fine particles.
Environmental studies on ethylparaben degradation show it undergoes relatively rapid biodegradation in wastewater treatment systems. However, its presence in aquatic environments continues to be monitored as part of broader emerging contaminant research. Recent advances in analytical chemistry have improved detection methods for trace levels in environmental samples.
Future research directions for CAS 120-47-8 include exploring its potential in combination preservative systems and developing more sustainable production methods. As the personal care industry evolves, ethylparaben remains a relevant subject in discussions about preservative efficacy versus consumer safety concerns.
120-47-8 (Ethylparaben) Related Products
- 94-18-8(Benzyl 4-\u200bHydroxybenzoate(Benzyl Paraben))
- 39630-68-7(Diethyl 5-hydroxyisophthalate)
- 77513-40-7(Benzoic acid, 3-hydroxy-, phenylmethyl ester)
- 84697-08-5(Benzoic acid,4-hydroxy-, 2-methoxyethyl ester)
- 35285-68-8(E 215)
- 5434-76-4(Benzoic acid,4-hydroxy-, phenylmethyl ester, zinc salt (2:1))
- 7781-98-8(Ethyl 3-hydroxybenzoate)
- 3236-64-4(Benzoic acid, 4-hydroxy-, 1,2-ethanediyl ester)
- 2496-90-4(2-Hydroxyethyl 4-hydroxybenzoate)
- 84833-58-9(Benzoic acid, 4-hydroxy-, (4-methylphenyl)methyl ester)
