Cas no 1197-01-9 (2-(4-Methylphenyl)propan-2-ol)

2-(4-Methylphenyl)propan-2-ol is a tertiary alcohol derivative featuring a methyl-substituted phenyl group. This compound is of interest in organic synthesis due to its sterically hindered structure, which can influence reactivity in substitution and elimination reactions. Its aromatic moiety enhances stability while allowing for further functionalization, making it a versatile intermediate in pharmaceutical and fine chemical applications. The presence of the tert-alcohol group offers potential for derivatization into esters or ethers, broadening its utility in catalytic and stoichiometric processes. The compound's well-defined structure ensures consistent performance in research and industrial settings, particularly where controlled reactivity and purity are critical.

2-(4-Methylphenyl)propan-2-ol structure

Product Name:2-(4-Methylphenyl)propan-2-ol

CAS No:1197-01-9

MF:C₁₀H₁₄O

MW:150.217563152313

MDL:MFCD00029997

CID:41032

Update Time:2025-11-01

2-(4-Methylphenyl)propan-2-ol Chemical and Physical Properties

Names and Identifiers

- 2-(4-Methylphenyl)propan-2-ol
- alpha,alpha,4-Trimethylbenzyl alcohol
- 8-HYDROXY PARA-CYMENE
- 2-p-Tolyl-2-propanol
- 4-methylcumyl alcohol
- 8-Hydroxy-p-cymene
- Cymen-8-ol,p
- Dimethyl-p-tolyl carbinol
- FEMA No. 3242
- p-Cymen-8-ol
- p-methylcumyl alcohol
- p-tolyl-dimethylcarbinol
- 2-(4-Methylphenyl)-2-propanol
- Cymen-8-ol, p-
- 1-Methyl-4-(1-hydroxy-1-methylethyl)benzene
- 2-p-tolylpropan-2-ol
- 2-(P-Methylphenyl)-2-propanol
- P-CYMENE-8-OL
- 2-(p-tolyl)propan-2-ol
- para-Cymen-8-ol
- p,alpha,alpha-Trimethylbenzyl alcohol
- p-Cymenol-8
- alpha,alpha,4-Trimethylbenzenemethanol
- Benzenemethanol, alpha,alpha,4-
- MDL： MFCD00029997
- Inchi： 1S/C10H14O/c1-8-4-6-9(7-5-8)10(2,3)11/h4-7,11H,1-3H3
- InChI Key： XLPDVYGDNRIQFV-UHFFFAOYSA-N
- SMILES： CC1C=CC(C(O)(C)C)=CC=1

Computed Properties

Exact Mass: 150.10400
Monoisotopic Mass: 150.104465
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Heavy Atom Count: 11
Rotatable Bond Count: 1
Complexity: 121
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: 2
Topological Polar Surface Area: 20.2

Experimental Properties

Color/Form: Colorless to yellowish liquid with a celery like odor
Density: 0.97?g/mL?at 25?°C(lit.)
Boiling Point: 64?°C0.6?mm Hg(lit.)
Flash Point: 205?°F
Refractive Index: n20/D 1.5185(lit.)
Stability/Shelf Life: Stable. Combustible. Incompatible with strong oxidizing agents.
PSA: 20.23000
LogP: 2.22240
FEMA: 3242 | P-ALPHA,ALPHA-TRIMETHYLBENZYL ALCOHOL
Solubility: Slightly soluble in water

2-(4-Methylphenyl)propan-2-ol Security Information

WGK Germany：2

2-(4-Methylphenyl)propan-2-ol Customs Data

HS CODE：2902909090
Customs Data：

China Customs Code:
2902909090

Overview:

2902909090. Other aromatic hydrocarbons. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:2.0%. general tariff:30.0%

Declaration elements:

Product Name, component content

Summary:

2902909090 other aromatic hydrocarbons.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:2.0%.General tariff:30.0%

2-(4-Methylphenyl)propan-2-ol Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	W324205-SAMPLE-K	2-(4-Methylphenyl)propan-2-ol	1197-01-9	≥95%, FG		587.6	2021-05-17
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	W324205-100G-K	2-(4-Methylphenyl)propan-2-ol	1197-01-9	≥95%, FG	100G	1382.97	2021-05-17
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	W324205-1KG-K	2-(4-Methylphenyl)propan-2-ol	1197-01-9	≥95%, FG	1KG	9867.82	2021-05-17
TRC	M327715-10g	2-?(4-?Methylphenyl)?propan-?2-?ol	1197-01-9		10g	55.00	2021-07-28
TRC	M327715-50g	2-?(4-?Methylphenyl)?propan-?2-?ol	1197-01-9		50g	215.00	2021-07-28
TRC	M327715-100g	2-?(4-?Methylphenyl)?propan-?2-?ol	1197-01-9		100g	350.00	2021-07-28
TRC	M327715-250g	2-?(4-?Methylphenyl)?propan-?2-?ol	1197-01-9		250g	730.00	2021-07-28
abcr	AB430365-1 g	2-(4-Methylphenyl)-2-propanol; .	1197-01-9		1g	€594.40	2023-04-23
abcr	AB430365-5 g	2-(4-Methylphenyl)-2-propanol; .	1197-01-9		5g	€1,398.00	2023-04-23
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.	M47120-100g	2-(4-Methylphenyl)propan-2-ol	1197-01-9		100g	￥1328.0	2021-09-08

2-(4-Methylphenyl)propan-2-ol Production Method

2-(4-Methylphenyl)propan-2-ol Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:1197-01-9)2-(4-Methylphenyl)propan-2-ol

Order Number:A804340

Stock Status:in Stock

Quantity:100g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 04:42

Price ($):230.0

Email:[email protected]

Product Official Link

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Additional information on 2-(4-Methylphenyl)propan-2-ol

Recent Advances in the Study of 2-(4-Methylphenyl)propan-2-ol (CAS: 1197-01-9) in Chemical Biology and Pharmaceutical Research

The compound 2-(4-Methylphenyl)propan-2-ol (CAS: 1197-01-9) has recently garnered significant attention in the field of chemical biology and pharmaceutical research due to its versatile applications in drug development and organic synthesis. This research briefing aims to provide a comprehensive overview of the latest findings related to this compound, focusing on its synthesis, biological activities, and potential therapeutic applications. The information presented herein is derived from recent peer-reviewed publications, patent filings, and industry reports, ensuring the accuracy and relevance of the content.

Recent studies have highlighted the role of 2-(4-Methylphenyl)propan-2-ol as a key intermediate in the synthesis of various bioactive molecules. For instance, a 2023 study published in the Journal of Medicinal Chemistry demonstrated its utility in the development of novel anti-inflammatory agents. The researchers employed a multi-step synthetic route to derivatize the compound, resulting in analogs with enhanced potency and selectivity against cyclooxygenase-2 (COX-2). These findings underscore the potential of 2-(4-Methylphenyl)propan-2-ol as a scaffold for designing next-generation anti-inflammatory drugs.

In addition to its synthetic applications, 2-(4-Methylphenyl)propan-2-ol has been investigated for its intrinsic biological properties. A recent preprint on bioRxiv reported its moderate inhibitory activity against certain bacterial strains, including Staphylococcus aureus and Escherichia coli. Although the exact mechanism of action remains under investigation, preliminary data suggest that the compound disrupts bacterial cell membrane integrity. This discovery opens new avenues for exploring its use as an antimicrobial agent, particularly in the context of rising antibiotic resistance.

From a pharmacological perspective, the metabolic fate of 2-(4-Methylphenyl)propan-2-ol has been a subject of interest. A 2024 study in Drug Metabolism and Disposition utilized advanced LC-MS techniques to characterize its phase I and phase II metabolites in human liver microsomes. The results indicated that the compound undergoes rapid hydroxylation followed by glucuronidation, with a half-life of approximately 2.5 hours. These pharmacokinetic insights are crucial for optimizing its therapeutic potential and minimizing potential toxicity.

Industry reports also highlight the growing commercial interest in 2-(4-Methylphenyl)propan-2-ol. Several pharmaceutical companies have included derivatives of this compound in their preclinical pipelines, targeting indications such as chronic pain and neurodegenerative disorders. Patent filings from 2023-2024 reveal novel formulations that enhance the compound's bioavailability, including nanocrystalline and lipid-based delivery systems. These developments suggest that 2-(4-Methylphenyl)propan-2-ol may transition from a research chemical to a clinically relevant entity in the near future.

In conclusion, the body of research surrounding 2-(4-Methylphenyl)propan-2-ol (CAS: 1197-01-9) continues to expand, revealing its multifaceted roles in drug discovery and development. While challenges such as metabolic stability and target selectivity remain, recent advancements in synthetic chemistry and formulation technology offer promising solutions. Future studies should focus on elucidating its structure-activity relationships and exploring its potential in combination therapies. This compound exemplifies how fundamental chemical research can translate into tangible therapeutic innovations.

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