Cas no 1196156-80-5 (1-pyrrolidin-3-ylpyrazole)

1-Pyrrolidin-3-ylpyrazole is a heterocyclic compound featuring a pyrazole ring linked to a pyrrolidine moiety at the 3-position. This structure imparts versatility in medicinal chemistry and drug discovery, particularly as a scaffold for designing bioactive molecules. Its fused ring system offers conformational rigidity, enhancing binding affinity to target proteins, while the nitrogen-rich framework allows for diverse functionalization. The compound is valued for its potential as a building block in synthesizing kinase inhibitors, CNS-active agents, and other pharmacologically relevant compounds. Its balanced lipophilicity and polarity contribute to favorable pharmacokinetic properties, making it a useful intermediate in optimizing drug candidates.
1-pyrrolidin-3-ylpyrazole structure
1-pyrrolidin-3-ylpyrazole structure
Product Name:1-pyrrolidin-3-ylpyrazole
CAS No:1196156-80-5
MF:C7H11N3
MW:137.182340860367
MDL:MFCD13189968
CID:2103441
PubChem ID:46318284
Update Time:2025-05-19

1-pyrrolidin-3-ylpyrazole Chemical and Physical Properties

Names and Identifiers

    • 1-(3-pyrrolidinyl)-1H-Pyrazole
    • 1-pyrrolidin-3-ylpyrazole
    • 815-754-3
    • AB69503
    • 1196156-80-5
    • 1-(PYRROLIDIN-3-YL)-1H-PYRAZOLE
    • ALBB-013312
    • WXB15680
    • AB69501
    • EN300-218781
    • SCHEMBL16975378
    • 1H-pyrazole, 1-(3-pyrrolidinyl)-, dihydrochloride
    • AKOS002659258
    • F8883-2837
    • (R)-1-(PYRROLIDIN-3-YL)-1H-PYRAZOLE
    • AKOS017470353
    • Z975915884
    • (S)-1-(PYRROLIDIN-3-YL)-1H-PYRAZOLE
    • DA-31139
    • AB69493
    • 1246543-31-6
    • MDL: MFCD13189968
    • Inchi: 1S/C7H11N3/c1-3-9-10(5-1)7-2-4-8-6-7/h1,3,5,7-8H,2,4,6H2
    • InChI Key: ZUZKWDPTWJFIPQ-UHFFFAOYSA-N
    • SMILES: N1CCC(C1)N1C=CC=N1

Computed Properties

  • Exact Mass: 137.095
  • Monoisotopic Mass: 137.095
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 115
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 29.8A^2
  • XLogP3: -0.1

1-pyrrolidin-3-ylpyrazole Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
P140376-100mg
1-(pyrrolidin-3-yl)-1h-pyrazole
1196156-80-5
100mg
$ 135.00 2022-06-03
TRC
P140376-500mg
1-(pyrrolidin-3-yl)-1h-pyrazole
1196156-80-5
500mg
$ 525.00 2022-06-03
TRC
P140376-1g
1-(pyrrolidin-3-yl)-1h-pyrazole
1196156-80-5
1g
$ 815.00 2022-06-03
Enamine
EN300-218781-0.05g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
0.05g
$70.0 2025-02-20
Enamine
EN300-218781-0.1g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
0.1g
$104.0 2025-02-20
Enamine
EN300-218781-0.25g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
0.25g
$149.0 2025-02-20
Enamine
EN300-218781-0.5g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
0.5g
$234.0 2025-02-20
Enamine
EN300-218781-1.0g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
1.0g
$300.0 2025-02-20
Enamine
EN300-218781-2.5g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
2.5g
$661.0 2025-02-20
Enamine
EN300-218781-5.0g
1-(pyrrolidin-3-yl)-1H-pyrazole
1196156-80-5 95.0%
5.0g
$1264.0 2025-02-20

Additional information on 1-pyrrolidin-3-ylpyrazole

Exploring the Versatile Applications and Properties of 1-Pyrrolidin-3-ylpyrazole (CAS No. 1196156-80-5)

The compound 1-Pyrrolidin-3-ylpyrazole (CAS No. 1196156-80-5) is a fascinating heterocyclic molecule that has garnered significant attention in recent years due to its unique structural features and potential applications in various fields. This article delves into the properties, synthesis, and diverse uses of this compound, while also addressing some of the most frequently asked questions by researchers and industry professionals.

Chemically, 1-Pyrrolidin-3-ylpyrazole belongs to the class of pyrazole derivatives, which are known for their wide range of biological activities and pharmaceutical applications. The presence of both pyrrolidine and pyrazole moieties in its structure makes it particularly interesting for drug discovery and material science applications. Recent studies have shown that compounds containing these structural motifs often exhibit improved pharmacokinetic properties compared to their simpler analogs.

One of the most common questions researchers ask about 1-Pyrrolidin-3-ylpyrazole is regarding its synthesis. The compound can be prepared through several synthetic routes, with the most efficient methods involving the condensation of appropriate pyrrolidine precursors with pyrazole derivatives. Recent advancements in green chemistry have led to more sustainable synthesis approaches, which is particularly relevant given the current focus on environmentally friendly chemical processes.

The pharmaceutical industry has shown considerable interest in 1-Pyrrolidin-3-ylpyrazole due to its potential as a drug scaffold. Many researchers are investigating its use in developing new therapeutic agents, particularly for neurological disorders and inflammatory conditions. This aligns with current trends in medicinal chemistry, where there's growing demand for novel heterocyclic compounds with improved target specificity and reduced side effects.

Beyond pharmaceutical applications, 1-Pyrrolidin-3-ylpyrazole has found use in material science as a building block for functional materials. Its ability to form stable complexes with various metal ions makes it valuable in catalysis and sensor development. This application is particularly timely, given the increasing need for efficient catalytic systems in industrial processes and environmental remediation technologies.

From a commercial perspective, the market for pyrrolidine-pyrazole hybrids like 1-Pyrrolidin-3-ylpyrazole has been steadily growing. The compound is now available from several specialty chemical suppliers, with purity grades ranging from research quantities to bulk industrial scales. This availability has facilitated its adoption across various research fields and industrial applications.

Recent computational studies on 1-Pyrrolidin-3-ylpyrazole have provided valuable insights into its molecular properties and potential interactions. These in silico investigations are particularly relevant in today's research landscape, where computer-aided drug design and material discovery are becoming increasingly important for accelerating development timelines and reducing experimental costs.

The stability and storage conditions of 1-Pyrrolidin-3-ylpyrazole are another area of frequent inquiry. Proper handling and storage are crucial for maintaining the compound's integrity, with recommendations typically including protection from moisture and storage at controlled temperatures. These considerations are especially important for researchers working with sensitive chemical compounds.

Looking to the future, 1-Pyrrolidin-3-ylpyrazole continues to be a compound of significant research interest. Its structural versatility makes it a promising candidate for further exploration in multiple scientific domains. As synthetic methodologies continue to advance and our understanding of structure-activity relationships deepens, we can expect to see even more innovative applications emerging for this intriguing molecule.

For researchers considering working with 1-Pyrrolidin-3-ylpyrazole, it's worth noting that several recent publications have explored its derivatives and analogs. These studies often provide valuable insights into structure-activity relationships that can guide future research directions. The compound's growing popularity in both academic and industrial settings suggests that it will remain an important focus of chemical research for years to come.

Recommended suppliers
Jinan Hanyu Chemical Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinan Hanyu Chemical Co.,Ltd.
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Amadis Chemical Company Limited