Cas no 1193389-16-0 (1-(4-fluorophenoxy)propan-2-amine hydrochloride)
1-(4-fluorophenoxy)propan-2-amine hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 1-(4-Fluorophenoxy)-2-propanaMine HCl
- 1-(4-fluorophenoxy)propan-2-amine hydrochloride
- 1-(2-aminopropoxy)-4-fluorobenzene hydrochloride
- CS-0453689
- F1989-0016
- 1-(4-fluorophenoxy)propan-2-amine;hydrochloride
- EN300-52043
- AKOS025296004
- 1193389-16-0
- C77796
-
- MDL: MFCD06247711
- Inchi: 1S/C9H12FNO.ClH/c1-7(11)6-12-9-4-2-8(10)3-5-9;/h2-5,7H,6,11H2,1H3;1H
- InChI Key: DZFKSENVDGIYBA-UHFFFAOYSA-N
- SMILES: Cl.FC1C=CC(=CC=1)OCC(C)N
Computed Properties
- Exact Mass: 205.0669699g/mol
- Monoisotopic Mass: 205.0669699g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 13
- Rotatable Bond Count: 3
- Complexity: 124
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 35.2?2
Experimental Properties
- Density: 1.1±0.1 g/cm3
- Boiling Point: 255.5±20.0 °C at 760 mmHg
- Flash Point: 108.3±21.8 °C
- Vapor Pressure: 0.0±0.5 mmHg at 25°C
1-(4-fluorophenoxy)propan-2-amine hydrochloride Security Information
- Signal Word:warning
- Hazard Statement: H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
1-(4-fluorophenoxy)propan-2-amine hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B435930-25mg |
1-(4-Fluorophenoxy)propan-2-amine Hydrochloride |
1193389-16-0 | 25mg |
$ 70.00 | 2022-06-07 | ||
| TRC | B435930-50mg |
1-(4-Fluorophenoxy)propan-2-amine Hydrochloride |
1193389-16-0 | 50mg |
$ 95.00 | 2022-06-07 | ||
| TRC | B435930-250mg |
1-(4-Fluorophenoxy)propan-2-amine Hydrochloride |
1193389-16-0 | 250mg |
$ 365.00 | 2022-06-07 | ||
| Enamine | EN300-52043-0.05g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 0.05g |
$106.0 | 2023-04-24 | |
| Enamine | EN300-52043-0.1g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 0.1g |
$157.0 | 2023-04-24 | |
| Enamine | EN300-52043-0.25g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 0.25g |
$225.0 | 2023-04-24 | |
| Enamine | EN300-52043-0.5g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 0.5g |
$355.0 | 2023-04-24 | |
| Enamine | EN300-52043-1.0g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 1g |
$455.0 | 2023-04-24 | |
| Enamine | EN300-52043-2.5g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 2.5g |
$754.0 | 2023-04-24 | |
| Enamine | EN300-52043-5.0g |
1-(4-fluorophenoxy)propan-2-amine hydrochloride |
1193389-16-0 | 95% | 5g |
$1254.0 | 2023-04-24 |
1-(4-fluorophenoxy)propan-2-amine hydrochloride Related Literature
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Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
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Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
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Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
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Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
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Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
Additional information on 1-(4-fluorophenoxy)propan-2-amine hydrochloride
Comprehensive Overview of 1-(4-fluorophenoxy)propan-2-amine hydrochloride (CAS No. 1193389-16-0)
1-(4-fluorophenoxy)propan-2-amine hydrochloride (CAS No. 1193389-16-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and biochemical research. This compound, characterized by its fluorophenoxy moiety and amine hydrochloride functional group, is widely studied for its potential applications in drug development and molecular biology. Researchers are particularly interested in its structural properties, which make it a valuable intermediate in synthesizing more complex molecules.
The compound's CAS number 1193389-16-0 serves as a unique identifier, ensuring precise tracking in chemical databases and regulatory frameworks. Its systematic name, 1-(4-fluorophenoxy)propan-2-amine hydrochloride, reflects its molecular structure, combining a fluorinated aromatic ring with an amine hydrochloride salt. This combination enhances its solubility and stability, making it suitable for various experimental conditions. Recent studies highlight its role in modulating specific biochemical pathways, though further research is needed to fully elucidate its mechanisms.
In the context of current trends, 1-(4-fluorophenoxy)propan-2-amine hydrochloride aligns with the growing demand for fluorinated compounds in medicinal chemistry. Fluorination is a key strategy to improve drug bioavailability and metabolic stability, topics frequently searched in academic and industrial circles. The compound's amine hydrochloride component also ties into discussions about salt formation to optimize physicochemical properties, a hot topic in formulation science.
From a synthetic perspective, the preparation of CAS No. 1193389-16-0 involves multi-step organic reactions, often starting with 4-fluorophenol and proceeding through nucleophilic substitution and subsequent amination. Researchers emphasize the importance of purity and yield in these processes, as impurities can significantly impact downstream applications. Analytical techniques such as HPLC, NMR, and mass spectrometry are routinely employed to characterize the compound, ensuring compliance with industry standards.
The versatility of 1-(4-fluorophenoxy)propan-2-amine hydrochloride extends to its potential use in central nervous system (CNS) drug discovery, a field experiencing rapid growth due to increasing neurological disorders. Its structural similarity to known bioactive molecules has prompted investigations into its receptor binding affinity and pharmacokinetic profile. These studies are often linked to broader searches for novel therapeutic agents and drug repurposing strategies.
Environmental and safety considerations are also critical when working with CAS No. 1193389-16-0. While not classified as hazardous under standard guidelines, proper handling protocols are essential to minimize risks. This aligns with the broader scientific community's focus on green chemistry and sustainable synthesis, topics frequently explored in contemporary literature.
In summary, 1-(4-fluorophenoxy)propan-2-amine hydrochloride (CAS No. 1193389-16-0) represents a promising compound with diverse applications in research and development. Its unique chemical properties, coupled with ongoing advancements in fluorinated drug design, position it as a subject of continued interest. As the scientific community delves deeper into its potential, this compound may pave the way for innovative solutions in healthcare and beyond.
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