• 1. Exciplex emission from the mixed dimer of naphthalene and 2-cyanonaphthalene in a supersonic jet
  Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
• 2. Evolution of calcium phosphate precipitation in hanging drop vapor diffusion by in situRaman microspectroscopy
  Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
• 3. Fast-pulsing NMR techniques for the detection of weak interactions: successful natural abundance probe of hydrogen bonds in peptides?
  Amandine Altmayer-Henzien,Valérie Declerck,David J. Aitken,Ewen Lescop,Denis Merlet,Jonathan Farjon Org. Biomol. Chem., 2013,11, 7611-7615
• 4. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 5. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
  J. Zagora,M. Vosla?,L. Schreiberová,I. Schreiber Phys. Chem. Chem. Phys., 2002,4, 1284-1291

5-(Allyloxy)-1H-pyrazol-3-amine: An Overview of a Promising Compound (CAS No. 1187875-99-5)

5-(Allyloxy)-1H-pyrazol-3-amine (CAS No. 1187875-99-5) is a versatile compound that has garnered significant attention in the fields of medicinal chemistry and pharmaceutical research. This compound, characterized by its unique chemical structure and potential biological activities, has been the subject of numerous studies aimed at elucidating its properties and applications.

The chemical structure of 5-(Allyloxy)-1H-pyrazol-3-amine consists of a pyrazole ring substituted with an allyloxy group at the 5-position and an amino group at the 3-position. The pyrazole ring is a five-membered heterocyclic compound with two nitrogen atoms, which is known for its diverse biological activities, including anti-inflammatory, anticonvulsant, and antitumor properties. The allyloxy group, on the other hand, introduces additional reactivity and functional versatility to the molecule.

Recent research has highlighted the potential of 5-(Allyloxy)-1H-pyrazol-3-amine in various therapeutic areas. One notable application is in the development of novel antiviral agents. Studies have shown that this compound exhibits potent antiviral activity against a range of viruses, including influenza and herpes simplex virus (HSV). The mechanism of action is believed to involve the inhibition of viral replication through the disruption of key viral enzymes or pathways.

In addition to its antiviral properties, 5-(Allyloxy)-1H-pyrazol-3-amine has also been investigated for its anti-inflammatory effects. In vitro studies have demonstrated that this compound can effectively reduce the production of pro-inflammatory cytokines such as TNF-α and IL-6, which are key mediators of inflammation. This makes it a promising candidate for the treatment of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

The pharmacokinetic properties of 5-(Allyloxy)-1H-pyrazol-3-amine have also been studied in detail. Research has shown that this compound exhibits good oral bioavailability and favorable pharmacokinetic profiles, making it suitable for further development as a therapeutic agent. Preclinical studies in animal models have demonstrated its safety and efficacy, paving the way for clinical trials.

In terms of synthetic methods, several efficient routes have been developed to synthesize 5-(Allyloxy)-1H-pyrazol-3-amine. One common approach involves the reaction of 3-amino-1H-pyrazole with allyl alcohol in the presence of a suitable catalyst. This method provides high yields and good purity, making it suitable for large-scale production.

The potential applications of 5-(Allyloxy)-1H-pyrazol-3-amine extend beyond its therapeutic uses. It has also been explored as a building block in organic synthesis due to its reactive functional groups. The allyloxy group can undergo various transformations such as allylation, epoxidation, and hydroboration, which can be used to synthesize more complex molecules with diverse biological activities.

In conclusion, 5-(Allyloxy)-1H-pyrazol-3-amine (CAS No. 1187875-99-5) is a promising compound with a wide range of potential applications in medicinal chemistry and pharmaceutical research. Its unique chemical structure and biological activities make it an attractive candidate for further investigation and development. As research in this area continues to advance, it is likely that new insights and applications will emerge, further solidifying the importance of this compound in the scientific community.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)