• 1. Emerging investigator series: heterogeneous reactions of sulfur dioxide on mineral dust nanoparticles: from single component to mixed components?
  Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
• 2. Excitable dynamics in the bromate–sulfite–ferrocyanide reaction
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• 3. Emerging 2D hybrid nanomaterials: towards enhanced sensitive and selective conductometric gas sensors at room temperature
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Aminopyridines and derivatives

Comprehensive Overview of 2-Chloropyridine-3,4-diamine hydrochloride (CAS No. 1187830-93-8)

2-Chloropyridine-3,4-diamine hydrochloride (CAS No. 1187830-93-8) is a specialized organic compound widely utilized in pharmaceutical and agrochemical research. Its molecular structure, featuring a chlorinated pyridine ring with diamine substituents, makes it a valuable intermediate for synthesizing heterocyclic compounds. Researchers frequently explore its applications in drug discovery, particularly for developing kinase inhibitors and antimicrobial agents. The hydrochloride salt form enhances solubility, facilitating its use in aqueous reaction systems.

The growing demand for pyridine derivatives in medicinal chemistry has spotlighted compounds like 2-Chloropyridine-3,4-diamine hydrochloride. Recent studies highlight its role in designing targeted therapies, aligning with trends in personalized medicine. Searches for "chloropyridine synthesis" or "diamine-based intermediates" often lead to this compound, reflecting its relevance in modern organic synthesis. Its stability under mild conditions further supports its adoption in multi-step reactions.

Analytical techniques such as HPLC and NMR spectroscopy are essential for verifying the purity of CAS 1187830-93-8. Industry professionals frequently inquire about "spectral data for 2-Chloropyridine-3,4-diamine" or "storage conditions for hydrochloride salts," underscoring the need for precise handling protocols. The compound typically requires protection from moisture and storage at controlled temperatures to maintain efficacy.

In agrochemical applications, 2-Chloropyridine-3,4-diamine hydrochloride serves as a precursor for crop protection agents. Its structural motifs contribute to herbicides and fungicides with improved environmental profiles—a key concern in "green chemistry" discussions. Regulatory-compliant synthesis methods for this compound are increasingly sought after, driven by global emphasis on sustainable production.

Future research directions may explore catalytic modifications of this intermediate to reduce waste generation. As AI-assisted molecular design gains traction, computational queries about "pyridine reactivity prediction" often reference this compound’s versatile behavior in nucleophilic substitution reactions. Such interdisciplinary interest reinforces its importance across scientific domains.

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