Cas no 1187386-15-7 (N-Methyl 2,4-difluoroaniline hydrochloride)

N-Methyl 2,4-difluoroaniline hydrochloride is a fluorinated aniline derivative commonly used as an intermediate in pharmaceutical and agrochemical synthesis. Its key advantages include high purity and stability, making it suitable for precise reactions in fine chemical applications. The presence of fluorine atoms enhances its reactivity in electrophilic substitution and coupling reactions, while the hydrochloride salt form improves solubility in polar solvents. This compound is particularly valuable in the development of active pharmaceutical ingredients (APIs) and specialty chemicals, where controlled functionalization is critical. Proper handling under inert conditions is recommended to maintain its integrity.
N-Methyl 2,4-difluoroaniline hydrochloride structure
1187386-15-7 structure
Product Name:N-Methyl 2,4-difluoroaniline hydrochloride
CAS No:1187386-15-7
MF:C7H8ClF2N
MW:179.594927787781
MDL:MFCD11110410
CID:857328
PubChem ID:46739565
Update Time:2025-11-06

N-Methyl 2,4-difluoroaniline hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 2,4-Difluoro-N-methylaniline hydrochloride
    • N-Methyl 2,4-difluoroaniline, HCl
    • A-5301
    • AK134297
    • I14-24529
    • KB-58467
    • N-methyl-2,4-difluoroaniline hydrochloride
    • DTXSID30675164
    • EN300-7390545
    • AKOS015908329
    • N-methyl-2,4-difluoroaniline hcl
    • 2,4-difluoro-N-methylaniline;hydrochloride
    • DB-361384
    • MFCD11110410
    • N-Methyl-2,4-difluoroaniline, HCl
    • N-Methyl 2,4-difluoroaniline HCl
    • 1187386-15-7
    • BS-23778
    • N-Methyl 2,4-difluoroaniline hydrochloride
    • G39465
    • 2,4-Difluoro-N-methylanilinehydrochloride
    • N-Methyl 2,4-difluoroaniline,hcl
    • 2,4-Difluoro-N-methylaniline--hydrogen chloride (1/1)
    • CS-0212509
    • MDL: MFCD11110410
    • Inchi: 1S/C7H7F2N.ClH/c1-10-7-3-2-5(8)4-6(7)9;/h2-4,10H,1H3;1H
    • InChI Key: YECUMCZQTXMOBR-UHFFFAOYSA-N
    • SMILES: Cl.FC1C=C(C=CC=1NC)F

Computed Properties

  • Exact Mass: 179.0313333g/mol
  • Monoisotopic Mass: 179.0313333g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 108
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 12?2

N-Methyl 2,4-difluoroaniline hydrochloride Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A019148302-10g
2,4-Difluoro-N-methylaniline hydrochloride
1187386-15-7 95%
10g
$480.76 2023-09-04
TRC
M301833-100mg
N-Methyl 2,4-difluoroaniline hydrochloride
1187386-15-7
100mg
$64.00 2023-05-18
TRC
M301833-250mg
N-Methyl 2,4-difluoroaniline hydrochloride
1187386-15-7
250mg
$98.00 2023-05-18
TRC
M301833-500mg
N-Methyl 2,4-difluoroaniline hydrochloride
1187386-15-7
500mg
$150.00 2023-05-18
TRC
M301833-1g
N-Methyl 2,4-difluoroaniline hydrochloride
1187386-15-7
1g
$207.00 2023-05-18
abcr
AB272665-1 g
N-Methyl 2,4-difluoroaniline HCl; 98%
1187386-15-7
1g
€212.00 2023-06-22
abcr
AB272665-5 g
N-Methyl 2,4-difluoroaniline HCl; 98%
1187386-15-7
5g
€552.00 2023-06-22
abcr
AB272665-1g
N-Methyl 2,4-difluoroaniline HCl, 98%; .
1187386-15-7 98%
1g
€212.00 2025-02-19
abcr
AB272665-5g
N-Methyl 2,4-difluoroaniline HCl, 98%; .
1187386-15-7 98%
5g
€552.00 2025-02-19
Enamine
EN300-7390545-0.05g
2,4-difluoro-N-methylaniline hydrochloride
1187386-15-7 95.0%
0.05g
$19.0 2025-03-11

Additional information on N-Methyl 2,4-difluoroaniline hydrochloride

N-Methyl 2,4-difluoroaniline hydrochloride: A Comprehensive Overview

N-Methyl 2,4-difluoroaniline hydrochloride, also known by its CAS number CAS No. 1187386-15-7, is a chemical compound that has garnered significant attention in the fields of pharmaceuticals and materials science. This compound is a derivative of aniline, with methyl and difluoro substituents, and exists in its hydrochloride form. The molecule's structure and properties make it a versatile compound with potential applications in drug development and as an intermediate in organic synthesis.

The molecular formula of N-Methyl 2,4-difluoroaniline hydrochloride is C8H9F2ClN·HCl, and its molecular weight is approximately 209.6 g/mol. The compound is typically a white to off-white crystalline solid, with a melting point of around 200°C. Its solubility in water is moderate, and it exhibits good solubility in common organic solvents such as dichloromethane and ethyl acetate. These physical properties make it suitable for various synthetic procedures in the laboratory setting.

From a chemical standpoint, N-Methyl 2,4-difluoroaniline hydrochloride is notable for its electronic properties. The presence of electron-withdrawing groups (the fluorine atoms) on the aromatic ring enhances the reactivity of the amine group. This makes the compound a valuable substrate for various nucleophilic substitutions and coupling reactions. Recent studies have explored its use in the synthesis of bioactive molecules, particularly in the development of potential antiviral agents.

In terms of applications, N-Methyl 2,4-difluoroaniline hydrochloride has found utility as an intermediate in the synthesis of more complex organic molecules. Its role as a building block in drug discovery has been highlighted in several recent research papers. For instance, researchers have utilized this compound to synthesize novel analogs of known pharmaceutical agents, leveraging its unique reactivity to create compounds with enhanced pharmacokinetic profiles.

The latest advancements in synthetic chemistry have further expanded the potential uses of N-Methyl 2,4-difluoroaniline hydrochloride. Scientists have developed efficient methods for its preparation, including one-pot synthesis routes that minimize waste and improve yield. These methods are particularly relevant for large-scale production in the pharmaceutical industry.

From an environmental perspective, understanding the fate and transport of N-Methyl 2,4-difluoroaniline hydrochloride is crucial for ensuring sustainable practices. Recent studies have focused on its biodegradation pathways under various environmental conditions. These findings are essential for assessing the compound's impact on ecosystems and guiding regulatory decisions regarding its use.

In conclusion, N-Methyl 2,4-difluoroaniline hydrochloride (CAS No. 1187386-15-7) stands out as a significant compound with diverse applications across multiple disciplines. Its chemical properties make it a valuable tool in organic synthesis and drug discovery. As research continues to uncover new insights into its behavior and potential uses, this compound is poised to play an even greater role in advancing scientific knowledge and technological innovation.

Recommended suppliers
鉅瀾化工科技(青島)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
鉅瀾化工科技(青島)有限公司
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Amadis Chemical Company Limited
Wuhan ChemNorm Biotech Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Wuhan ChemNorm Biotech Co.,Ltd.