Cas no 1187174-14-6 (5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride)
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride is a fluorinated tetrahydroisoquinoline derivative with potential applications in medicinal chemistry and pharmaceutical research. The incorporation of fluorine atoms at the 5 and 7 positions enhances the compound's metabolic stability and bioavailability, making it a valuable intermediate for drug discovery. Its hydrochloride salt form improves solubility and handling properties. This compound is particularly useful in the synthesis of bioactive molecules targeting neurological and cardiovascular systems, owing to the tetrahydroisoquinoline scaffold's prevalence in pharmacologically active agents. High purity and well-characterized structure ensure reproducibility in research applications.
1187174-14-6 structure
Product Name:5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride
CAS No:1187174-14-6
MF:C9H10ClF2N
MW:205.632208347321
CID:1090037
PubChem ID:45074009
Update Time:2025-06-08
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical and Physical Properties
Names and Identifiers
-
- 5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride
- 5,7-difluoro-1,2,3,4-tetrahydro-Isoquinoline hydrochloride
- 5,7-DIFLUORO-1,2,3,4-TETRAHYDROISOQUINOLINE HCl
- 5,7-Difluoro-1,2,3,4-tetrahydroisoquinolinehydrochloride
- 5,7-difluoro-1,2,3,4-tetrahydroisoquinoline,hydrochloride
- 5,7-DI-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLINE hydrochloride
- 1187174-14-6
- 5,7-difluoro-1,2,3,4-tetrahydroisoquinoline;hydrochloride
- 5,7-DI-FLUORO-1,2,3,4-TETRAHYDROISOQUINOLINE HCl
- 5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline--hydrogen chloride (1/1)
- DB-012175
- DTXSID50662879
-
- Inchi： 1S/C9H9F2N.ClH/c10-7-3-6-5-12-2-1-8(6)9(11)4-7;/h3-4,12H,1-2,5H2;1H
- InChI Key： UZQSODBRCWJIRO-UHFFFAOYSA-N
- SMILES： Cl.FC1=CC(=CC2CNCCC=21)F
Computed Properties
- Exact Mass: 205.0469833g/mol
- Monoisotopic Mass: 205.0469833g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 13
- Rotatable Bond Count: 0
- Complexity: 163
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 12?2
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A189004610-1g |
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride |
1187174-14-6 | 98% | 1g |
$504.90 | 2023-09-04 | |
| Chemenu | CM145410-1g |
5,7-Di-fluoro-1,2,3,4-tetrahydroIsoquinoline hydrochloride |
1187174-14-6 | 98% | 1g |
$574 | 2021-08-05 | |
| Chemenu | CM145410-1g |
5,7-Di-fluoro-1,2,3,4-tetrahydroIsoquinoline hydrochloride |
1187174-14-6 | 98% | 1g |
$594 | 2023-11-23 | |
| Ambeed | A107469-1g |
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride |
1187174-14-6 | 98% | 1g |
$495.0 | 2024-04-25 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1759546-1g |
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride |
1187174-14-6 | 98% | 1g |
￥4851.00 | 2024-08-09 |
5,7-Difluoro-1,2,3,4-tetrahydroisoquinoline hydrochloride Related Literature
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Saeideh Mirfakhraei,Malak Hekmati,Fereshteh Hosseini Eshbala,Hojat Veisi New J. Chem., 2018,42, 1757-1761
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Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
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Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
-
Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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