Cas no 1186194-94-4 (2-Amino-5-phenyl-3-(trifluoromethyl)pyridine)
2-Amino-5-phenyl-3-(trifluoromethyl)pyridine is a fluorinated pyridine derivative with a phenyl substituent at the 5-position and a trifluoromethyl group at the 3-position. This compound serves as a versatile intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of bioactive molecules. The presence of both amino and trifluoromethyl groups enhances its reactivity, enabling selective functionalization for applications in medicinal chemistry. Its structural features contribute to improved metabolic stability and lipophilicity, making it valuable in drug discovery. The compound is typically handled under controlled conditions due to its sensitivity. High-purity grades are available for research and industrial use, ensuring consistent performance in synthetic applications.
1186194-94-4 structure
Product Name:2-Amino-5-phenyl-3-(trifluoromethyl)pyridine
CAS No:1186194-94-4
MF:C12H9F3N2
MW:238.208472967148
CID:3160899
PubChem ID:45790819
Update Time:2025-06-06
2-Amino-5-phenyl-3-(trifluoromethyl)pyridine Chemical and Physical Properties
Names and Identifiers
-
- 2-Amino-5-phenyl-3-(trifluoromethyl)pyridine
- 5-phenyl-3-(trifluoromethyl)pyridin-2-amine
- 2-Pyridinamine, 5-phenyl-3-(trifluoromethyl)-
- 1186194-94-4
- A1-36123
- AKOS005256581
-
- Inchi： 1S/C12H9F3N2/c13-12(14,15)10-6-9(7-17-11(10)16)8-4-2-1-3-5-8/h1-7H,(H2,16,17)
- InChI Key： NHRFASOKUBRKIP-UHFFFAOYSA-N
- SMILES： C1(N)=NC=C(C2=CC=CC=C2)C=C1C(F)(F)F
Computed Properties
- Exact Mass: 238.07178278Da
- Monoisotopic Mass: 238.07178278Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 17
- Rotatable Bond Count: 1
- Complexity: 249
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3
- Topological Polar Surface Area: 38.9?2
2-Amino-5-phenyl-3-(trifluoromethyl)pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1620696-2.5g |
5-Phenyl-3-(trifluoromethyl)pyridin-2-amine |
1186194-94-4 | 98% | 2.5g |
￥17395.00 | 2024-08-09 |
2-Amino-5-phenyl-3-(trifluoromethyl)pyridine Related Literature
-
Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
-
Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
1186194-94-4 (2-Amino-5-phenyl-3-(trifluoromethyl)pyridine) Related Products
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
CN Supplier
Reagent
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier
CN Supplier
Bulk
Shanghai Jinhuan Chemical CO., LTD.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shanghai Pearlk Chemicals Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Shandong Jing Kun Chemical Co.,Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
