Cas no 1184982-16-8 (4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride)

4-Methyl-1,3-thiazole-5-carboxylic acid hydrochloride is a heterocyclic compound featuring a thiazole core substituted with a methyl group at the 4-position and a carboxylic acid moiety at the 5-position, in its hydrochloride salt form. This derivative is valuable in pharmaceutical and agrochemical research due to its role as a versatile intermediate in synthesizing biologically active molecules. The hydrochloride salt enhances solubility and stability, facilitating handling and reactivity in synthetic applications. Its structural features make it suitable for constructing complex scaffolds, particularly in medicinal chemistry for drug discovery. The compound’s purity and well-defined properties ensure reproducibility in experimental and industrial settings.
4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride structure
1184982-16-8 structure
Product Name:4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride
CAS No:1184982-16-8
MF:C5H6ClNO2S
MW:179.624639034271
CID:2130465
Update Time:2025-05-21

4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 4-Methylthiazole-5-carboxylic acid hydrochloride
    • 4-Methylthiazole-5-carboxylic acidhydrochloride
    • 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride
    • Inchi: 1S/C5H5NO2S.ClH/c1-3-4(5(7)8)9-2-6-3;/h2H,1H3,(H,7,8);1H
    • InChI Key: CCZDMKMGHUZRQQ-UHFFFAOYSA-N
    • SMILES: Cl.S1C=NC(C)=C1C(=O)O

Computed Properties

  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 128
  • Topological Polar Surface Area: 78.4

4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride Pricemore >>

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4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride Related Literature

Additional information on 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride

Comprehensive Overview of 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride (CAS 1184982-16-8)

4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride (CAS 1184982-16-8) is a heterocyclic compound that has garnered significant attention in pharmaceutical and agrochemical research. This thiazole derivative is widely recognized for its versatile applications in drug discovery and material science. With the increasing demand for novel bioactive molecules, 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride has become a key intermediate in synthesizing various therapeutic agents.

The compound belongs to the thiazole family, characterized by a five-membered ring containing sulfur and nitrogen atoms. Its unique structure contributes to its reactivity and potential as a building block in organic synthesis. Researchers have explored its role in developing antimicrobial agents, anti-inflammatory drugs, and anticancer compounds, making it a subject of interest in modern medicinal chemistry.

One of the most searched questions regarding 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride is its solubility and stability under different conditions. Studies indicate that this compound exhibits moderate solubility in water and polar organic solvents, which is crucial for its application in pharmaceutical formulations. Additionally, its hydrochloride salt form enhances stability, making it suitable for long-term storage and handling in laboratory settings.

In recent years, the demand for thiazole-based compounds has surged due to their potential in addressing antibiotic resistance—a global health concern. 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride has been investigated for its role in developing next-generation antibacterial agents, particularly against multidrug-resistant pathogens. This aligns with current trends in pharmaceutical research, where scientists are actively seeking alternatives to conventional antibiotics.

Another area of growing interest is the use of 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride in agrochemical applications. The compound's structural features make it a promising candidate for designing pesticides and herbicides with improved efficacy and environmental safety. Researchers are exploring its potential to target specific enzymes in pests while minimizing harm to non-target organisms, addressing the increasing demand for sustainable agricultural solutions.

The synthesis of 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride typically involves multi-step organic reactions, including condensation and cyclization processes. Advanced techniques such as microwave-assisted synthesis and flow chemistry have been employed to optimize yield and purity, reflecting the ongoing innovation in chemical manufacturing. These methods not only improve efficiency but also reduce waste, aligning with the principles of green chemistry.

From a commercial perspective, the market for thiazole derivatives like 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride is expanding, driven by the pharmaceutical and agrochemical industries. Suppliers and manufacturers are increasingly focusing on high-purity grades to meet the stringent requirements of research and development. This compound is often listed under various catalog numbers, making it essential for buyers to verify the CAS 1184982-16-8 when sourcing materials.

In conclusion, 4-methyl-1,3-thiazole-5-carboxylic acid hydrochloride (CAS 1184982-16-8) represents a valuable chemical entity with diverse applications in modern science. Its role in addressing critical challenges such as antibiotic resistance and sustainable agriculture underscores its importance in contemporary research. As scientific advancements continue, this compound is expected to remain at the forefront of innovation in medicinal and agrochemical chemistry.

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