Cas no 118055-01-9 (2-{pyrazolo1,5-apyridin-3-yl}acetonitrile)
2-{Pyrazolo[1,5-a]pyridin-3-yl}acetonitrile is a versatile heterocyclic compound featuring a pyrazolo[1,5-a]pyridine core with an acetonitrile substituent at the 3-position. This structure makes it a valuable intermediate in pharmaceutical and agrochemical synthesis, particularly for constructing nitrogen-rich scaffolds. Its reactive nitrile group enables further functionalization through nucleophilic addition or cyclization reactions. The compound’s fused bicyclic system enhances rigidity, potentially improving binding affinity in drug discovery applications. It is commonly employed in the development of kinase inhibitors and other biologically active molecules. High purity grades are available to ensure reproducibility in research and industrial processes. Proper handling under inert conditions is recommended due to its sensitivity to moisture and air.
118055-01-9 structure
Product Name:2-{pyrazolo1,5-apyridin-3-yl}acetonitrile
CAS No:118055-01-9
MF:C9H7N3
MW:157.171981096268
CID:131735
PubChem ID:14145807
Update Time:2025-05-27
2-{pyrazolo1,5-apyridin-3-yl}acetonitrile Chemical and Physical Properties
Names and Identifiers
-
- Pyrazolo[1,5-a]pyridine-3-acetonitrile
- 2-pyrazolo[1,5-a]pyridin-3-ylacetonitrile
- 2-{pyrazolo1,5-apyridin-3-yl}acetonitrile
- 118055-01-9
- EN300-172410
- 2-{PYRAZOLO[1,5-A]PYRIDIN-3-YL}ACETONITRILE
- SCHEMBL1290838
- 2-(pyrazolo[1,5-a]pyridin-3-yl)acetonitrile
- DTXSID10556548
- (Pyrazolo[1,5-a]pyridin-3-yl)acetonitrile
-
- Inchi： 1S/C9H7N3/c10-5-4-8-7-11-12-6-2-1-3-9(8)12/h1-3,6-7H,4H2
- InChI Key： KPFQTJKLNKNOCO-UHFFFAOYSA-N
- SMILES： N12C=CC=CC1=C(CC#N)C=N2
Computed Properties
- Exact Mass: 157.06411
- Monoisotopic Mass: 157.063997236g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 12
- Rotatable Bond Count: 1
- Complexity: 205
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.7
- Topological Polar Surface Area: 41.1?2
Experimental Properties
- PSA: 41.09
2-{pyrazolo1,5-apyridin-3-yl}acetonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM272449-1g |
2-(Pyrazolo[1,5-a]pyridin-3-yl)acetonitrile |
118055-01-9 | 97% | 1g |
$1019 | 2023-02-18 | |
| Enamine | EN300-172410-1g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 1g |
$1070.0 | 2023-09-20 | |
| Enamine | EN300-172410-5g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 5g |
$3105.0 | 2023-09-20 | |
| Enamine | EN300-172410-10g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 10g |
$4606.0 | 2023-09-20 | |
| Enamine | EN300-172410-0.05g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 0.05g |
$249.0 | 2023-09-20 | |
| Enamine | EN300-172410-0.1g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 0.1g |
$372.0 | 2023-09-20 | |
| Enamine | EN300-172410-0.25g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 0.25g |
$530.0 | 2023-09-20 | |
| Enamine | EN300-172410-0.5g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 0.5g |
$835.0 | 2023-09-20 | |
| Enamine | EN300-172410-1.0g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 1g |
$1070.0 | 2023-05-23 | |
| Enamine | EN300-172410-2.5g |
2-{pyrazolo[1,5-a]pyridin-3-yl}acetonitrile |
118055-01-9 | 95% | 2.5g |
$2100.0 | 2023-09-20 |
2-{pyrazolo1,5-apyridin-3-yl}acetonitrile Related Literature
-
Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
-
Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
-
Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
-
Siquan Zhang,Shengyao Wang,Liping Guo,Hao Chen,Bien Tan,Shangbin Jin J. Mater. Chem. C, 2020,8, 192-200
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