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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

Comprehensive Overview of tert-butyl N-(3-amino-1,1-dimethyl-propyl)carbamate hydrochloride (CAS No. 1179359-61-5)

The compound tert-butyl N-(3-amino-1,1-dimethyl-propyl)carbamate hydrochloride (CAS No. 1179359-61-5) is a specialized carbamate derivative widely utilized in pharmaceutical and organic synthesis. Its unique structure, featuring a tert-butyl group and an amino functionality, makes it a valuable intermediate in the development of bioactive molecules. Researchers and industry professionals frequently search for this compound due to its role in peptide synthesis, drug discovery, and medicinal chemistry. The hydrochloride salt form enhances its stability and solubility, which is critical for laboratory and industrial applications.

In recent years, the demand for tert-butyl N-(3-amino-1,1-dimethyl-propyl)carbamate hydrochloride has surged alongside advancements in small-molecule therapeutics and protease inhibitors. This compound is often associated with the synthesis of kinase inhibitors and GPCR-targeted drugs, which are hot topics in modern pharmacology. Users searching for CAS 1179359-61-5 or related terms like "carbamate protecting group" or "amino acid derivatives" are typically interested in its synthetic pathways, purity standards, and commercial availability. The compound's relevance in high-throughput screening and combinatorial chemistry further underscores its importance in drug development pipelines.

The chemical properties of tert-butyl N-(3-amino-1,1-dimethyl-propyl)carbamate hydrochloride include a molecular weight of approximately 238.75 g/mol and a white to off-white crystalline appearance. Its hydrochloride salt form ensures better handling and storage conditions, addressing common concerns about compound degradation and moisture sensitivity. Analytical techniques such as HPLC, NMR, and mass spectrometry are routinely employed to verify its purity and structural integrity. These attributes align with the growing emphasis on quality control and regulatory compliance in the pharmaceutical industry.

From an SEO perspective, queries like "tert-butyl carbamate uses", "CAS 1179359-61-5 supplier", and "amino-protecting groups in organic synthesis" reflect the diverse applications of this compound. Its role in peptide coupling reactions and N-terminal protection strategies is particularly noteworthy, as these are frequently discussed in academic and industrial forums. Additionally, the compound's compatibility with solid-phase synthesis and automated peptide synthesizers makes it a staple in bioconjugation and protein engineering workflows.

Environmental and safety considerations for tert-butyl N-(3-amino-1,1-dimethyl-propyl)carbamate hydrochloride are also a focal point for users. While it is not classified as hazardous under standard regulations, proper handling protocols—such as the use of personal protective equipment (PPE) and ventilation systems—are recommended. This aligns with broader industry trends toward green chemistry and sustainable synthesis, which prioritize minimizing waste and reducing toxic byproducts.

In summary, tert-butyl N-(3-amino-1,1-dimethyl-propyl)carbamate hydrochloride (CAS No. 1179359-61-5) is a versatile and high-value compound with significant applications in pharmaceutical research and organic synthesis. Its robust chemical properties, coupled with its relevance to cutting-edge therapeutic development, ensure its continued prominence in scientific literature and commercial markets. For researchers seeking reliable data on this compound, understanding its synthetic utility and analytical benchmarks is essential for optimizing its use in drug design and molecular biology.

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