Cas no 115939-25-8 (Salvianolic acid B)

Salvianolic acid B is a bioactive phenolic compound derived from Salvia miltiorrhiza (Danshen), known for its potent antioxidant and anti-inflammatory properties. As a major water-soluble constituent, it exhibits significant pharmacological activities, including cardioprotective, neuroprotective, and hepatoprotective effects. Its mechanism involves scavenging free radicals, inhibiting lipid peroxidation, and modulating signaling pathways such as NF-κB and MAPK. Salvianolic acid B is widely studied for its potential in treating cardiovascular diseases, ischemic injuries, and fibrosis. With high purity and stability, it serves as a valuable reference standard in research and drug development. Its dual role in oxidative stress reduction and tissue protection makes it a promising candidate for therapeutic applications.
Salvianolic acid B structure
Salvianolic acid B structure
Product Name:Salvianolic acid B
CAS No:115939-25-8
MF:C36H30O16
MW:718.613811969757
CID:63190
PubChem ID:11629084
Update Time:2025-11-11

Salvianolic acid B Chemical and Physical Properties

Names and Identifiers

    • Salvianolic acid B
    • [2R-[2a,3b-(R*),4[E(R*)]]]-3-Benzofurancarboxylic acid 4-[3-[1-carboxy-2-(3,4-dihydroxy-phenyl) ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydrophenyl)-2,3-dihydro-7-hydroxyl-3-[1-carboxy-2-(3,4-dihydroxyphenyl) ethyl] ester
    • Lithospermate-B
    • SALVIANOLIC ACID B (RG)
    • Salvianolic
    • SALVIANICACIDB
    • (R)-2-(((2R,3R)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic aci
    • 2-(((2S,3S)-4-((E)-3-((R)-1-CARBOXY-2-(3,4-DIHYDROXYPHENYL)ETHOXY)-3-OXOPROP-1-EN-1-YL)-2-(3,4-DIHYDROXYPHENYL)-7-HYDROXY-2,3-DIHYDROBENZOFURAN-3-CARBONYL)OXY)-3-(3,4-DIHYDROXYPHENYL)PROPANOIC ACID
    • Salvianolic acid B
    • 4-[2-[1-carboxy-2-(3,4-dihydroxy-phenyl)-ethoxycarbonyl]-vinyl]2-(3,4-dihydroxy-phenyl)-7-hydroxy-2,3-dihydro-benzofuran-3-carboxylic acid 1-carboxy-(3,4-dihydroxy-phenyl)-ethyl ester
    • 4-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxybenzofuran-3-carboxylic acid 3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester
    • [2R-[2a,3b-(R*),4[E(R*)]]]-3-Benzofurancarboxylic acid 4-[3-[1-carboxy-2-(3,4-dihydroxy-phenyl) ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydrophenyl)-2,3-dihydro-7-hydroxyl-3-[1-carboxy-2-(3,4-dihydroxyphen
    • danfensuan
    • SALVIANOLIC ACID B(P)
    • SALVIANOLIC ACID B(RG)(CALL)
    • Powdered Chinese Salvia Extract (1 g)
    • Isosalvianolic acid B
    • BCP28200
    • alpha,alpha'-[Oxycarbonyl[2,3-dihydro-2-(3,4-dihydroxyphenyl)-7-hydroxybenzofuran-3,4-diyl]vinylenecarbonyloxy]bis(3,4-dihydroxybenzenepropionic acid)
    • 3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-(3,4-dihydroxyphenyl)-3-[3-(3,4-dihydroxyphenyl)-1-hydroxy-1-oxopropan-2-yl]oxycarbonyl-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxypropanoic acid
    • (R)-2-(((2R,3R)-4-((E)-3-((R)-1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-en-1-yl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid
    • BCP12410
    • (2R)-2-[(E)-3-[(2R,3R)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl]oxy-3-(3,4-dihydroxyphenyl)propanoic acid
    • 2-[3-[3-[1-Carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihy
    • Bitter Melon P.E.
    • MFCD23115783
    • Salvianolic-acid-B
    • (R)-2-((2R,3R)-4-((E)-3-((R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxoprop-1-enyl)-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydrobenzofuran-3-carbonyloxy)-3-(3,4-dihydroxyphenyl)propanoic acid
    • CHEMBL3747259
    • Danshensuan B
    • AKOS015920258
    • AS-56980
    • Danfensuan B
    • 121521-90-2
    • 115939-25-8
    • Salvianic acid B
    • (2R)-2-{[(2E)-3-[(2R,3R)-3-{[(1R)-1-CARBOXY-2-(3,4-DIHYDROXYPHENYL)ETHOXY]CARBONYL}-2-(3,4-DIHYDROXYPHENYL)-7-HYDROXY-2,3-DIHYDRO-1-BENZOFURAN-4-YL]PROP-2-ENOYL]OXY}-3-(3,4-DIHYDROXYPHENYL)PROPANOIC ACID
    • 1607436-77-0
    • SALVIANOLIC ACID B 98.0% BY HPLC
    • 115939-25-8;Lithospermic acid B; Danfensuan B; Salvianic acid B
    • 2-[3-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyloxy]-3-(3,4-dihydroxyphenyl)propanoic acid
    • NS00018034
    • FT-0674512
    • SNKFFCBZYFGCQN-PDVBOLEISA-N
    • BRD-K18898553-001-01-1
    • MDL： MFCD22125310
    • Inchi： 1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31-,32+/m1/s1
    • InChI Key： SNKFFCBZYFGCQN-PDVBOLEISA-N
    • SMILES： O1C2C(=CC=C(/C=C/C(=O)O[C@@H](C(=O)O)CC3C=CC(=C(C=3)O)O)C=2[C@@H](C(=O)O[C@@H](C(=O)O)CC2C=CC(=C(C=2)O)O)[C@@H]1C1C=CC(=C(C=1)O)O)O

Computed Properties

  • Exact Mass: 718.15300
  • Monoisotopic Mass: 718.153
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 9
  • Hydrogen Bond Acceptor Count: 16
  • Heavy Atom Count: 52
  • Rotatable Bond Count: 14
  • Complexity: 1290
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 4
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 278
  • XLogP3: 4

Experimental Properties

  • Color/Form: Powder
  • Density: 1.6370
  • Boiling Point: 1020.3 °C at 760 mmHg
  • Flash Point: 322.1 °C
  • Refractive Index: 1.739
  • PSA: 278.04000
  • LogP: 3.33450
  • Sensitiveness: Sensitive to light

Salvianolic acid B Security Information

Salvianolic acid B Customs Data

  • HS CODE：29329990

Salvianolic acid B Pricemore >>

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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:115939-25-8)Momordica
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Quantity:25KG,200KG,1000KG
Purity:99%
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(CAS:115939-25-8)salvianolicacidB
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Salvianolic acid B Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Salvianolic acid B Related Literature

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Additional information on Salvianolic acid B

Salvianolic acid B (CAS No. 115939-25-8): A Comprehensive Overview of Its Biochemical Profile and Therapeutic Applications

Salvianolic acid B, a naturally occurring polyphenolic compound derived from the Salvia miltiorrhiza plant, has garnered significant attention in the field of pharmaceutical research due to its multifaceted biological activities. With a CAS No. 115939-25-8, this compound is recognized for its potential in various therapeutic applications, particularly in cardiovascular and neuroprotective treatments. The growing body of scientific literature underscores the importance of Salvianolic acid B in modern medicine, highlighting its role as a promising candidate for drug development.

The biochemical properties of Salvianolic acid B make it a unique molecule with a complex structure that includes phenolic hydroxyl groups and a furan ring. These structural features contribute to its potent antioxidant, anti-inflammatory, and cardioprotective effects. Recent studies have demonstrated that Salvianolic acid B can modulate multiple signaling pathways, including those involved in endothelial function, platelet aggregation, and neuroprotection. Such findings have positioned this compound as a key player in the development of novel therapeutic strategies.

In the realm of cardiovascular health, Salvianolic acid B has been extensively studied for its ability to improve blood flow and reduce oxidative stress. Research indicates that this compound can enhance the production of nitric oxide, a vasodilator that helps relax blood vessels and lower blood pressure. Additionally, Salvianolic acid B has shown promise in reducing myocardial injury by attenuating inflammatory responses and preventing cell death. These effects make it a valuable component in the management of cardiovascular diseases such as hypertension and myocardial infarction.

The neuroprotective properties of Salvianolic acid B are another area of intense interest. Studies have revealed that this compound can protect against neurodegenerative diseases by inhibiting oxidative damage and reducing inflammation in brain cells. For instance, research on Alzheimer's disease has shown that Salvianolic acid B can mitigate the accumulation of amyloid-beta plaques, a hallmark of this condition. Furthermore, preclinical trials have suggested that Salvianolic acid B may have potential benefits in treating Parkinson's disease by protecting dopaminergic neurons from oxidative stress.

Beyond its cardiovascular and neuroprotective roles, Salvianolic acid B has also been explored for its anti-cancer properties. Emerging evidence suggests that this compound can induce apoptosis in cancer cells while sparing healthy cells. Its ability to inhibit key enzymes involved in tumor growth, such as cyclooxygenase-2 (COX-2), makes it a promising candidate for cancer therapy. Additionally, Salvianolic acid B has demonstrated anti-microbial activity, showing efficacy against various bacterial and fungal strains. This broad spectrum of activity positions it as a versatile compound with potential applications in multiple therapeutic areas.

The pharmacokinetics of Salvianolic acid B have been carefully studied to optimize its delivery and efficacy. Research has shown that oral administration of this compound is well-tolerated with minimal side effects. However, its bioavailability can be limited due to rapid metabolism in the liver. To overcome this challenge, researchers are exploring novel formulations such as nanoparticles and liposomes to enhance its absorption and distribution throughout the body. These advancements aim to improve the therapeutic outcomes of Salvianolic acid B in clinical settings.

The future direction of research on Salvianolic acid B is promising, with ongoing studies focusing on elucidating its mechanisms of action and identifying new therapeutic applications. Collaborative efforts between academia and industry are essential to translate these findings into clinical practice. As our understanding of the biochemical pathways influenced by Salvianolic acid B continues to grow, so too will its potential as a therapeutic agent.

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Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:115939-25-8)Momordica
LE641;LE2468954
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
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Hubei Cuiyuan Biotechnology Co.,Ltd
(CAS:115939-25-8)salvianolicacidB
CRN0013
Purity:≥98%
Quantity:5mg/20mg/50mg
Price ($):Inquiry
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