Cas no 115843-99-7 (4-Bromo-3-chloro-2-fluoroaniline)
4-Bromo-3-chloro-2-fluoroaniline Chemical and Physical Properties
Names and Identifiers
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- 4-Bromo-3-chloro-2-fluoroaniline
- Benzenamine,4-bromo-3-chloro-2-fluoro-
- BUTTPARK 89\07-45
- 4-bromo-3-chloro-2-fluorobenzenamine
- EN300-134740
- WYXZIQDHENNEPU-UHFFFAOYSA-N
- (4-Bromo-3-chloro-2-fluorophenyl)amine
- A803493
- CS-0103942
- DTXSID90382226
- SY022863
- PS-10198
- AKOS005255700
- MFCD04039280
- J-514712
- Benzenamine, 4-bromo-3-chloro-2-fluoro-
- FT-0677920
- 4-bromanyl-3-chloranyl-2-fluoranyl-aniline
- Z1269194938
- 4-bromo-3-chloro-2-fluoro-aniline
- 115843-99-7
- SCHEMBL159571
- DB-060754
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- MDL： MFCD04039280
- Inchi： 1S/C6H4BrClFN/c7-3-1-2-4(10)6(9)5(3)8/h1-2H,10H2
- InChI Key： WYXZIQDHENNEPU-UHFFFAOYSA-N
- SMILES： BrC1C=CC(=C(C=1Cl)F)N
Computed Properties
- Exact Mass: 222.92000
- Monoisotopic Mass: 222.92
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 124
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 3
- Topological Polar Surface Area: 26A^2
Experimental Properties
- Color/Form: No data avaiable
- Density: 1.8±0.1 g/cm3
- Melting Point: 51-53°C
- Boiling Point: 262.7±35.0 °C at 760 mmHg
- Flash Point: 112.7±25.9 °C
- Refractive Index: 1.611
- PSA: 26.02000
- LogP: 3.40500
- Vapor Pressure: 0.0±0.5 mmHg at 25°C
4-Bromo-3-chloro-2-fluoroaniline Security Information
- Signal Word：warning
- Hazard Statement： Irritant
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - Safety Instruction： H303+H313+H333
-
Hazardous Material Identification：
- HazardClass：IRRITANT
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
4-Bromo-3-chloro-2-fluoroaniline Customs Data
- HS CODE：2921420090
- Customs Data：
China Customs Code:
2921420090Overview:
2921420090 Other aniline derivatives and their salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
4-Bromo-3-chloro-2-fluoroaniline Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 024545-1g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98% | 1g |
￡10.00 | 2022-03-01 | |
| Fluorochem | 024545-5g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98% | 5g |
￡11.00 | 2022-03-01 | |
| Fluorochem | 024545-25g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98% | 25g |
￡19.00 | 2022-03-01 | |
| Fluorochem | 024545-100g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98% | 100g |
￡74.00 | 2022-03-01 | |
| Fluorochem | 024545-500g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98% | 500g |
￡324.00 | 2022-03-01 | |
| Apollo Scientific | PC48291-25g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98% | 25g |
￡42.00 | 2023-09-01 | |
| Apollo Scientific | PC48291-100g |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 98+% | 100g |
￡77.00 | 2025-02-21 | |
| TRC | B685533-10mg |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 10mg |
$ 50.00 | 2022-06-06 | ||
| TRC | B685533-50mg |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 50mg |
$ 65.00 | 2022-06-06 | ||
| TRC | B685533-100mg |
4-Bromo-3-chloro-2-fluoroaniline |
115843-99-7 | 100mg |
$ 80.00 | 2022-06-06 |
4-Bromo-3-chloro-2-fluoroaniline Suppliers
Audited Supplier
4-Bromo-3-chloro-2-fluoroaniline Related Literature
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Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
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Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
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Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
Additional information on 4-Bromo-3-chloro-2-fluoroaniline
4-Bromo-3-chloro-2-fluoroaniline: A Comprehensive Overview
4-Bromo-3-chloro-2-fluoroaniline (CAS No. 115843-99-7) is a heteroaromatic compound with significant applications in various fields of chemistry. This compound, characterized by its unique substitution pattern on the aniline ring, has garnered attention due to its potential in drug discovery, material science, and environmental chemistry. The presence of bromine, chlorine, and fluorine substituents introduces distinct electronic and steric effects, making it a valuable molecule for both academic and industrial research.
The synthesis of 4-bromo-3-chloro-2-fluoroaniline involves multi-step processes that typically begin with the halogenation of aniline derivatives. Recent advancements in catalytic methods have enabled more efficient and selective synthesis pathways. For instance, the use of transition metal catalysts such as palladium has been reported to enhance the yield and purity of this compound. These methods are not only environmentally friendly but also scalable for industrial production.
In terms of chemical properties, 4-bromo-3-chloro-2-fluoroaniline exhibits a high melting point due to its strong intermolecular hydrogen bonding and aromaticity. Its solubility in polar solvents is moderate, which makes it suitable for various solution-based reactions. The compound's reactivity is influenced by the electron-withdrawing effects of bromine and chlorine atoms, which direct electrophilic substitution reactions to specific positions on the aromatic ring.
Recent studies have explored the application of 4-bromo-3-chloro-2-fluoroaniline in drug design. Its ability to act as a building block for bioactive molecules has been highlighted in several research papers. For example, researchers have utilized this compound as a precursor for synthesizing potential anticancer agents. The substitution pattern on the aniline ring allows for easy functionalization, enabling the creation of diverse pharmacophores with desired biological activities.
The environmental impact of 4-bromo-3-chloro-2-fluoroaniline has also been a topic of interest. Studies have shown that this compound undergoes biodegradation under specific conditions, reducing its persistence in natural ecosystems. However, further research is needed to fully understand its fate and toxicity in various environmental compartments.
In conclusion, 4-bromo-3-chloro-2-fluoroaniline (CAS No. 115843-99-7) is a versatile compound with promising applications across multiple disciplines. Its unique chemical properties and synthetic accessibility make it an invaluable tool for researchers seeking to develop novel materials and pharmaceuticals. As ongoing studies continue to uncover new insights into its behavior and utility, this compound is poised to play an increasingly important role in modern chemistry.
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