Cas no 1156602-69-5 (1-(4-fluorophenyl)-1H-pyrazol-4-amine)

1-(4-Fluorophenyl)-1H-pyrazol-4-amine is a fluorinated pyrazole derivative with notable utility as a versatile intermediate in organic synthesis and pharmaceutical research. Its structural features, including the 4-fluorophenyl group and the reactive amine functionality at the 4-position of the pyrazole ring, make it a valuable building block for the development of biologically active compounds. The compound exhibits favorable stability and reactivity, enabling its use in cross-coupling reactions, heterocyclic modifications, and the synthesis of potential drug candidates. Its well-defined chemical properties and consistent purity ensure reliable performance in research applications, particularly in medicinal chemistry and agrochemical development.

1-(4-fluorophenyl)-1H-pyrazol-4-amine structure

1156602-69-5 structure

Product Name:1-(4-fluorophenyl)-1H-pyrazol-4-amine

CAS No:1156602-69-5

MF:C₉H₈FN₃

MW:177.178324699402

MDL:MFCD12192664

CID:894761

PubChem ID:43531715

Update Time:2025-05-20

1-(4-fluorophenyl)-1H-pyrazol-4-amine Chemical and Physical Properties

Names and Identifiers

- 1-(4-fluorophenyl)-1H-pyrazol-4-amine
- 1-(4-fluorophenyl)pyrazol-4-amine
- UBKWWOPAKRZWTI-UHFFFAOYSA-N
- MFCD12192664
- AKOS009581179
- F73744
- CS-0258602
- Z431510022
- 1156602-69-5
- AB65396
- (4-fluorophenyl)-1 h -pyrazol-4-amine
- SCHEMBL15779430
- EN300-70596
- DB-123289
- MDL： MFCD12192664
- Inchi： 1S/C9H8FN3/c10-7-1-3-9(4-2-7)13-6-8(11)5-12-13/h1-6H,11H2
- InChI Key： UBKWWOPAKRZWTI-UHFFFAOYSA-N
- SMILES： FC1C=CC(=CC=1)N1C=C(C=N1)N

Computed Properties

Exact Mass: 177.07022543g/mol
Monoisotopic Mass: 177.07022543g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 13
Rotatable Bond Count: 1
Complexity: 168
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
XLogP3: 1.3
Topological Polar Surface Area: 43.8?2

1-(4-fluorophenyl)-1H-pyrazol-4-amine Pricemore >>

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Chemenu	CM486653-1g	1-(4-Fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	97%	1g	$396	2022-06-14
eNovation Chemicals LLC	D632212-500mg	1-(4-Fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	500mg	$395	2024-06-03
eNovation Chemicals LLC	D632212-1g	1-(4-Fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	1g	$575	2024-06-03
Enamine	EN300-70596-0.05g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	0.05g	$127.0	2023-07-06
Enamine	EN300-70596-0.1g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	0.1g	$189.0	2023-07-06
Enamine	EN300-70596-0.25g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	0.25g	$270.0	2023-07-06
Enamine	EN300-70596-0.5g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	0.5g	$426.0	2023-07-06
Enamine	EN300-70596-1.0g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	1.0g	$546.0	2023-07-06
Enamine	EN300-70596-2.5g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	2.5g	$1147.0	2023-07-06
Enamine	EN300-70596-5.0g	1-(4-fluorophenyl)-1H-pyrazol-4-amine	1156602-69-5	95%	5.0g	$2266.0	2023-07-06

1-(4-fluorophenyl)-1H-pyrazol-4-amine Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:1156602-69-5)1-(4-fluorophenyl)-1H-pyrazol-4-amine

Order Number:A1223788

Stock Status:in Stock

Quantity:1g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 22:42

Price ($):238

Email:[email protected]

Product Official Link

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Additional information on 1-(4-fluorophenyl)-1H-pyrazol-4-amine

1-(4-Fluorophenyl)-1H-Pyrazol-4-Amine: A Comprehensive Overview

The compound 1-(4-fluorophenyl)-1H-pyrazol-4-amine, identified by the CAS number 1156602-69-5, has garnered significant attention in the fields of organic chemistry and pharmacology. This molecule, characterized by its unique structure featuring a pyrazole ring substituted with a fluorophenyl group and an amine functionality, has been extensively studied for its potential applications in drug discovery and materials science. Recent advancements in synthetic methodologies and computational modeling have further elucidated its properties and mechanisms of action.

The synthesis of 1-(4-fluorophenyl)-1H-pyrazol-4-amine typically involves multi-step reactions, often leveraging the reactivity of amines and aromatic systems. Researchers have optimized these processes to enhance yield and purity, employing techniques such as microwave-assisted synthesis and catalytic transformations. The compound's stability under various conditions has been evaluated, revealing its suitability for use in diverse chemical environments.

In terms of biological activity, 1-(4-fluorophenyl)-1H-pyrazol-4-amine has demonstrated promising results in vitro, particularly in assays targeting specific enzymes and receptors. Recent studies have highlighted its potential as a modulator of kinase activity, a property that could be harnessed in the development of anti-cancer therapies. Additionally, its ability to interact with G-protein coupled receptors (GPCRs) suggests applications in the treatment of neurological disorders.

The structural versatility of this compound has also made it a valuable component in materials science. Its incorporation into polymer matrices has been explored for applications ranging from sensors to drug delivery systems. The fluorophenyl group imparts unique electronic properties, while the pyrazole ring contributes to hydrogen bonding capabilities, enhancing the material's functionality.

From an environmental standpoint, the ecological impact of 1-(4-fluorophenyl)-1H-pyrazol-4-amine has been a subject of recent research. Studies indicate that it exhibits low toxicity towards aquatic organisms under standard testing conditions, which aligns with regulatory requirements for chemical safety. However, ongoing investigations are focused on understanding its long-term persistence and degradation pathways in various ecosystems.

In conclusion, 1-(4-fluorophenyl)-1H-pyrazol-4-amine stands as a versatile and intriguing molecule with vast potential across multiple disciplines. Its continued exploration through cutting-edge research methodologies will undoubtedly unlock new avenues for its utilization in both therapeutic and industrial contexts.

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