Cas no 1156542-30-1 (2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine)

2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine is a halogenated pyridine derivative with significant utility in pharmaceutical and agrochemical synthesis. Its key structural features—a bromine substituent at the 2-position, a fluorine at the 5-position, and a trifluoromethyl group at the 4-position—enhance its reactivity in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, making it a valuable intermediate for constructing complex heterocyclic frameworks. The presence of multiple electron-withdrawing groups also facilitates nucleophilic aromatic substitution, broadening its applicability in medicinal chemistry. This compound exhibits high purity and stability, ensuring consistent performance in demanding synthetic processes. Its versatility and well-defined reactivity profile make it a preferred choice for researchers developing novel bioactive molecules.

2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine structure

1156542-30-1 structure

Product Name:2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine

CAS No:1156542-30-1

MF:C₆H₂BrF₄N

MW:243.984394550323

MDL:MFCD18259807

CID:1063661

PubChem ID:56604232

Update Time:2025-06-07

2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine Chemical and Physical Properties

Names and Identifiers

- 2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine
- 2-bromo-5-fluoro-4-trifluoromethylpyridine
- CFKUMEAWTPZERA-UHFFFAOYSA-N
- AK312702
- F10129
- Pyridine, 2-bromo-5-fluoro-4-(trifluoromethyl)-
- 2-Bromo-5-fluoro-4-trifluoromethyl-pyridine
- DS-11848
- SY070295
- 1156542-30-1
- AMY17304
- DB-313710
- SCHEMBL2332252
- CS-0103524
- MFCD18259807
- AKOS023838750
- SB30893
- MDL： MFCD18259807
- Inchi： 1S/C6H2BrF4N/c7-5-1-3(6(9,10)11)4(8)2-12-5/h1-2H
- InChI Key： CFKUMEAWTPZERA-UHFFFAOYSA-N
- SMILES： BrC1C=C(C(=CN=1)F)C(F)(F)F

Computed Properties

Exact Mass: 242.93067g/mol
Monoisotopic Mass: 242.93067g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Heavy Atom Count: 12
Rotatable Bond Count: 0
Complexity: 160
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 12.9
XLogP3: 2.9

Experimental Properties

Density: 1.786±0.06 g/cm3 (20 oC 760 Torr),
Boiling Point: 188.1±35.0 oC (760 Torr),
Flash Point: 67.6±25.9 oC,
Solubility: Slightly soluble (1 g/l) (25 o C),

2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
Fluorochem	069672-250mg	2-Bromo-5-fluoro-4-trifluoromethylpyridine	1156542-30-1	95%	250mg	￡252.00	2022-03-01
Fluorochem	069672-1g	2-Bromo-5-fluoro-4-trifluoromethylpyridine	1156542-30-1	95%	1g	￡563.00	2022-03-01
Fluorochem	069672-5g	2-Bromo-5-fluoro-4-trifluoromethylpyridine	1156542-30-1	95%	5g	￡1735.00	2022-03-01
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-CZ213-50mg	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine	1156542-30-1	95+%	50mg	602.0CNY	2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-CZ213-1g	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine	1156542-30-1	95+%	1g	4810.0CNY	2021-07-12
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-CZ213-200mg	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine	1156542-30-1	95+%	200mg	1411.0CNY	2021-07-12
abcr	AB528058-250 mg	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine; .	1156542-30-1		250MG	€345.60	2023-04-17
abcr	AB528058-1 g	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine; .	1156542-30-1		1g	€905.90	2023-04-17
Apollo Scientific	PC421205-1g	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine	1156542-30-1	95%	1g	￡419.00	2025-02-21
Chemenu	CM244022-1g	2-Bromo-5-fluoro-4-(trifluoromethyl)pyridine	1156542-30-1	95%	1g	$608	2021-08-04