• 1. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
• 2. Emergence of microfluidic wearable technologies
  Joo Chuan Yeo,Kenry Lab Chip, 2016,16, 4082-4090
• 3. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 4. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 5. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

N~1~-Phenyl-β-alaninamide Hydrochloride (CAS No. 115022-95-2): A Comprehensive Overview

N~1~-Phenyl-β-alaninamide Hydrochloride, identified by its CAS number 115022-95-2, is a compound of significant interest in the field of pharmaceutical chemistry and biochemistry. This compound, belonging to the amide class, has garnered attention due to its unique structural properties and potential biological activities. The hydrochloride salt form enhances its solubility, making it a valuable candidate for various research applications.

The molecular structure of N~1~-Phenyl-β-alaninamide Hydrochloride consists of a phenyl group attached to an β-alanine backbone, with an amide linkage. This configuration suggests potential interactions with biological targets such as enzymes and receptors. The presence of the hydrochloride moiety further influences its pharmacokinetic profile, contributing to its stability and bioavailability.

Recent studies have highlighted the compound's potential in modulating biological pathways relevant to inflammation and neurodegeneration. For instance, research indicates that N~1~-Phenyl-β-alaninamide Hydrochloride may interact with inflammatory cytokine pathways, offering a novel approach to developing anti-inflammatory agents. Additionally, its structural similarity to certain neuroprotective compounds has prompted investigations into its role in neurodegenerative diseases.

In vitro studies have demonstrated the compound's ability to inhibit the activity of specific enzymes involved in pro-inflammatory pathways. This inhibition suggests that N~1~-Phenyl-β-alaninamide Hydrochloride could serve as a lead compound for the development of new therapeutic agents targeting chronic inflammatory conditions. The compound's mechanism of action appears to involve precise modulation of signaling cascades, thereby reducing pathological inflammation.

The hydrochloride salt form of N~1~-Phenyl-β-alaninamide Hydrochloride offers several advantages in terms of formulation and delivery. Its enhanced solubility compared to the free base form allows for more efficient absorption and distribution within biological systems. This property is particularly crucial in drug development, where optimal solubility can significantly impact therapeutic efficacy.

Current research is also exploring the potential applications of N~1~-Phenyl-β-alaninamide Hydrochloride in combination therapies. The compound's ability to interact with multiple biological targets makes it a promising candidate for synergistic approaches in treating complex diseases. For example, its potential role in both anti-inflammatory and neuroprotective mechanisms could make it valuable in managing conditions where these pathways are intertwined.

From a synthetic chemistry perspective, the synthesis of N~1~-Phenyl-β-alaninamide Hydrochloride involves multi-step reactions that require precise control over reaction conditions. Advanced synthetic methodologies have been employed to optimize yield and purity, ensuring that researchers have access to high-quality material for their studies. These synthetic advancements have also facilitated the exploration of analogues and derivatives of this compound.

The pharmacological profile of N~1~-Phenyl-β-alaninamide Hydrochloride is further being elucidated through preclinical studies. These studies aim to determine its safety profile, optimal dosing regimens, and potential side effects. The results from these trials will provide critical insights into its therapeutic potential and guide future clinical development efforts.

In conclusion, N~1~-Phenyl-β-alaninamide Hydrochloride (CAS No. 115022-95-2) represents a significant area of research in pharmaceutical chemistry. Its unique structural features and potential biological activities make it a valuable compound for investigating new therapeutic strategies. As research continues to uncover its mechanisms of action and applications, this compound is poised to play a crucial role in the development of innovative treatments for various diseases.

• 262614-49-3(3-Amino-N-(4-(dimethylamino)phenyl)propanamide)
• 23043-12-1(Propanamide,N-(4-aminophenyl)-3-(diethylamino)-)
• 854813-77-7(N-(4-aminophenyl)-3-(dimethylamino)propanamide)
• 1346598-63-7(N-Phenylpropanamide-d3)
• 7500-98-3(N-[4-(acetylamino)phenyl]propanamide)
• 36332-50-0(4,5-Dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one hydrochloride)
• 621-10-3(N,N'-diphenylpropanediamide)
• 59690-89-0(N-(4-Aminophenyl)propanamide)
• 72066-84-3(Propanamide,N-(3-aminophenyl)-, hydrochloride (1:1))
• 57528-64-0(3-Amino-N-phenylpropanamide)