Cas no 115-53-7 (Sinomenine)

Sinomenine is an alkaloid compound extracted from the Sinomenium acutum plant, exhibiting notable anti-inflammatory and immunomodulatory properties. Its key advantages include reduced inflammation and oxidative stress in various biological systems, potentially offering therapeutic benefits for conditions such as arthritis and multiple sclerosis.
Sinomenine structure
Sinomenine structure
Product Name:Sinomenine
CAS No:115-53-7
MF:C19H23NO4
MW:329.39022564888
MDL:MFCD00134303
CID:35806
PubChem ID:5459308
Update Time:2026-01-16

Sinomenine Chemical and Physical Properties

Names and Identifiers

    • Sinomenine
    • 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-mo
    • 9-alpha,13-alpha,14-alpha-morphinan-6-one,7,8-didehydro-4-hydroxy-3,7-dimethox
    • rphinan-6-one
    • y-17-methyl-
    • SABIANINE A
    • SINOMENIN
    • (9alpha,13alpha,14alpha)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
    • (9Alpha,13alpha,14alpha)-4-hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one hydrochloride
    • COCULINE
    • CUCOLINE
    • KUKOLINE
    • SINOMENINE(RG)
    • SNM
    • 63LT81K70N
    • cuculine
    • sinomenine A bismethyliodide
    • Sinomenine,(S)
    • Sinomenine(C
    • Sinomenine (Cucoline)
    • UNII-63LT81K70N
    • BDBM224031
    • BDBM50241298
    • NCGC00161641-02
    • CCG-39100
    • BRN 0095280
    • NS00018030
    • C09643
    • Spectrum5_001621
    • INYYVPJSBIVGPH-QHRIQVFBSA-N
    • SR-05000002170-3
    • 3-(4-Fluorophenyl)-3-(toluene-4-sulfonylamino)-propionicacid
    • 115-53-7
    • morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9alpha,13alpha,14alpha)-
    • CCRIS 1550
    • NCGC00161641-05
    • KBioGR_002508
    • Spectrum3_001134
    • 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9-alpha,13-alpha,14-alpha-morphinan-6-one
    • Spectrum4_001981
    • Sinomenine 100 microg/mL in Acetonitrile
    • UPCMLD-DP085
    • AKOS000265568
    • NP51
    • BS-42101
    • DTXSID00871595
    • AC-8025
    • EINECS 204-094-6
    • (1R,9S,10R)-3-Hydroxy-4,12-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one
    • 9-alpha,13-alpha,14-alpha-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-
    • NSC785175
    • AKOS015960539
    • Sinomenine, 0.3 mol chloroform of crystallization
    • CS-0003778
    • BRD-K83459933-001-02-1
    • Spectrum2_001242
    • s2359
    • AKOS016023715
    • 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
    • SR-05000002170
    • NSC-785175
    • SMP1_000273
    • HY-15122
    • SR-05000002170-2
    • SCHEMBL363812
    • Q7524904
    • SW219295-1
    • NCGC00161641-01
    • NCGC00161641-04
    • 5-21-13-00516 (Beilstein Handbook Reference)
    • SINOMENINE [MI]
    • SPBio_001144
    • KBio3_002127
    • CHEBI:9163
    • SINOMENINE [WHO-DD]
    • BSPBio_002627
    • 4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one
    • CHEMBL248095
    • SPECTRUM1505253
    • BCP20032
    • (1R,9S,10S)-3-hydroxy-4,12-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5,11-tetraen-13-one
    • UPCMLD-DP085:001
    • BCBcMAP01_000195
    • MORPHINAN-6-ONE, 7,8-DIDEHYDRO-4-HYDROXY-3,7-DIMETHOXY-17-METHYL-, (9.ALPHA.,13.ALPHA.,14.ALPHA.)-
    • 14-Episinomenine
    • MLSMR
    • Kukoline hydrochloride
    • MLS001360420
    • SMR001223871
    • Cucoline hydrochloride
    • ALBB-020908
    • (1R,9S,10S)-3-hydroxy-4,12-dimethoxy-17-methyl-17-azatetracyclo(7.5.3.01,10.02,7)heptadeca-2(7),3,5,11-tetraen-13-one
    • BRD-K83459933-001-05-4
    • morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, (9alpha,13alpha,14alpha)-, hydrochloride
    • (+)-Coculine
    • (1R,9S,10S)-3-hydroxy-4,12-dimethoxy-17-methyl-17-azatetracyclo[7.5.3.0(1),(1)?.0(2),?]heptadeca-2(7),3,5,11-tetraen-13-one
    • FS09811
    • 204-094-6
    • MDL： MFCD00134303
    • Inchi： 1S/C19H23NO4/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9,12-13,22H,6-8,10H2,1-3H3/t12-,13+,19-/m1/s1
    • InChI Key： INYYVPJSBIVGPH-QHRIQVFBSA-N
    • SMILES： O(C)C1C(C[C@@]23C4C(=C(C=CC=4C[C@@H]([C@H]2C=1)N(C)CC3)OC)O)=O
    • BRN： 0095280

Computed Properties

  • Exact Mass: 329.16300
  • Monoisotopic Mass: 329.16270821 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 2
  • Complexity: 562
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 3
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 59
  • Surface Charge: 0
  • Tautomer Count: 35
  • XLogP3: 2.2
  • Molecular Weight: 329.4

Experimental Properties

  • Color/Form: Powder
  • Density: 1.2012 (rough estimate)
  • Melting Point: 180?°C (dec.)(lit.)
  • Boiling Point: 466.98°C (rough estimate)
  • Flash Point: 264.4 °C
  • Refractive Index: 1.5000 (estimate)
  • PSA: 59.00000
  • LogP: 1.95600
  • Solubility: Insoluble in water.
  • Merck: 13,8620
  • Specific Rotation: D26 -71° (c = 2.1 in alc)

Sinomenine Security Information

  • Hazardous Material transportation number：UN 1544
  • WGK Germany：3
  • Hazard Category Code： R22: harmful if swallowed. R36/37/38: irritating to eyes, respiratory tract and skin.
  • Safety Instruction： 53-22-26-36/37/39-45
  • FLUKA BRAND F CODES：9
  • RTECS：QD2170000
  • Hazardous Material Identification： T
  • Storage Condition：Keep it tightly closed. Store in a cool, dry place.
  • Safety Term：6.1(b)
  • Packing Group：III
  • Risk Phrases：R45
  • HazardClass：6.1(b)
  • PackingGroup：III
  • Toxicity：LD50 orally in mice: 580 mg/kg (Fu)
  • Packing Group：III
  • Hazard Level：6.1(b)

Sinomenine Pricemore >>

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ChemScence
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SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
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 ￥388.0 2021-09-07
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Sinomenine Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:115-53-7)Sinomenine
Order Number:LE10333
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:03
Price ($):discuss personally

Sinomenine Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Sinomenine Related Literature

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Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:115-53-7)Sinomenine
LE10333
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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