• 1. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 2. Estimation of activation energy for electroporation and pore growth rate in liquid crystalline and gel phases of lipid bilayers using molecular dynamics simulations?
  Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
• 3. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
• 4. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 5. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409

Comprehensive Introduction to 2-{1-(tert-butoxy)carbonylhydrazin-1-yl}ethan-1-ol (CAS No. 114897-60-8)

2-{1-(tert-butoxy)carbonylhydrazin-1-yl}ethan-1-ol (CAS No. 114897-60-8) is a specialized organic compound widely utilized in pharmaceutical intermediates, peptide synthesis, and bioconjugation. Its unique structure, featuring a tert-butoxycarbonyl (Boc) protected hydrazine moiety and a hydroxyl group, makes it a versatile building block in modern organic chemistry. Researchers and manufacturers increasingly seek this compound due to its role in drug discovery, proteomics, and biomarker development, aligning with trends in personalized medicine and targeted therapies.

The growing demand for Boc-protected hydrazine derivatives like 2-{1-(tert-butoxy)carbonylhydrazin-1-yl}ethan-1-ol reflects advancements in click chemistry and ligand design. Its compatibility with carbodiimide coupling reactions and stability under mild conditions are frequently discussed in scientific forums. Recent studies highlight its application in antibody-drug conjugates (ADCs), a hot topic in oncology research, where precise drug delivery systems are critical. Users searching for "Boc-hydrazine applications" or "hydroxyl-functionalized hydrazine derivatives" often encounter this compound as a key reagent.

From a synthetic perspective, CAS No. 114897-60-8 offers advantages in protecting group strategies. The Boc group can be selectively deprotected under acidic conditions without affecting other functional groups, a feature highly valued in multistep syntheses. This aligns with frequent search queries such as "Boc deprotection methods" or "hydrazine derivatives in peptide synthesis". Additionally, its ethanolamine backbone enhances solubility in polar solvents, addressing common challenges in water-sensitive reactions.

Quality control of 2-{1-(tert-butoxy)carbonylhydrazin-1-yl}ethan-1-ol is another area of interest. Analytical techniques like HPLC, NMR, and mass spectrometry are essential to verify purity, as impurities may affect downstream applications. Industry professionals often search for "CAS 114897-60-8 specifications" or "Boc-hydrazine analytical data", emphasizing the need for reliable characterization protocols. Storage recommendations (e.g., under inert gas at low temperatures) are also frequently queried to ensure compound stability.

In conclusion, 2-{1-(tert-butoxy)carbonylhydrazin-1-yl}ethan-1-ol represents a critical tool in synthetic and medicinal chemistry. Its relevance to high-throughput screening and biocompatible crosslinking ensures sustained interest, while its adaptability to green chemistry principles (e.g., reduced waste generation) resonates with contemporary sustainability goals. As research evolves, this compound will likely remain pivotal in addressing complex chemical biology challenges.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)