Cas no 114468-03-0 (3-(1,1-Difluoroethyl)pyridine)
3-(1,1-Difluoroethyl)pyridine is a fluorinated pyridine derivative characterized by the presence of a difluoroethyl substituent at the 3-position of the pyridine ring. This compound is of interest in pharmaceutical and agrochemical research due to its potential as a versatile building block for the synthesis of biologically active molecules. The difluoroethyl group enhances lipophilicity and metabolic stability, which can influence the pharmacokinetic properties of derived compounds. Its unique electronic and steric effects make it valuable in the design of enzyme inhibitors and receptor modulators. The compound is typically handled under inert conditions due to its sensitivity to moisture and air. Suitable for use in cross-coupling reactions and nucleophilic substitutions.
3-(1,1-Difluoroethyl)pyridine structure
Product Name:3-(1,1-Difluoroethyl)pyridine
CAS No:114468-03-0
MF:C7H7F2N
MW:143.133988618851
MDL:MFCD12404951
CID:132402
PubChem ID:640478
Update Time:2025-06-07
3-(1,1-Difluoroethyl)pyridine Chemical and Physical Properties
Names and Identifiers
-
- Pyridine,3-(1,1-difluoroethyl)-
- 3-(1,1-Difluoroethyl)pyridine
- Pyridine,3-(1,1-difluoroethyl)-(9CI)
- 2,2-Difluoro-2-(3-pyridyl)ethane
- AC1LD0RW
- c1-7(8,9)6-3-2-4-10-5-6
- C7H7F2N
- FT-0686160
- h2-5H,1H
- MolPort-004-757-686
- 3-(1,1-Difluoro-ethyl)-pyridine
- MFCD12404951
- CS-0441428
- DTXSID50348742
- WFCYXXQJORJHPH-UHFFFAOYSA-O
- InChI=1/C7H7F2N/c1-7(8,9)6-3-2-4-10-5-6/h2-5H,1H
- 114468-03-0
- AKOS005258047
- SCHEMBL13557773
- pyridine, 3-(1,1-difluoroethyl)-
- DTXCID80299814
- BBL101296
- STL555092
-
- MDL： MFCD12404951
- Inchi： 1S/C7H7F2N/c1-7(8,9)6-3-2-4-10-5-6/h2-5H,1H3
- InChI Key： WFCYXXQJORJHPH-UHFFFAOYSA-N
- SMILES： FC(C)(C1C=NC=CC=1)F
Computed Properties
- Exact Mass: 143.05465555g/mol
- Monoisotopic Mass: 143.05465555g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 114
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.7
- Topological Polar Surface Area: 12.9?2
3-(1,1-Difluoroethyl)pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | 070850-500mg |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 95% | 500mg |
2826.0CNY | 2021-07-05 | |
| Chemenu | CM317233-5g |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 95% | 5g |
$788 | 2021-08-18 | |
| Matrix Scientific | 070850-1g |
3-(1,1-Difluoroethyl)pyridine, 95% |
114468-03-0 | 95% | 1g |
$268.00 | 2023-09-08 | |
| Matrix Scientific | 070850-5g |
3-(1,1-Difluoroethyl)pyridine, 95% |
114468-03-0 | 95% | 5g |
$938.00 | 2023-09-08 | |
| TRC | D485295-50mg |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 50mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D485295-100mg |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 100mg |
$ 95.00 | 2022-06-05 | ||
| TRC | D485295-500mg |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 500mg |
$ 340.00 | 2022-06-05 | ||
| Apollo Scientific | PC520688-500mg |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 97% | 500mg |
￡160.00 | 2023-09-02 | |
| Apollo Scientific | PC520688-1g |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 97% | 1g |
￡272.00 | 2023-09-02 | |
| Apollo Scientific | PC520688-5g |
3-(1,1-Difluoroethyl)pyridine |
114468-03-0 | 97% | 5g |
￡960.00 | 2023-09-02 |
3-(1,1-Difluoroethyl)pyridine Related Literature
-
Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
-
Amit Kumar Majhi,Subbarao Kanchi,V. Venkataraman,K. G. Ayappa,Prabal K. Maiti Soft Matter, 2015,11, 8632-8640
-
Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
-
Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
114468-03-0 (3-(1,1-Difluoroethyl)pyridine) Related Products
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- 694434-72-5(PYRIDINE, 3-ETHYL-, COMPD. WITH HYDRAZINE AND (TRIFLUOROMETHYL)BENZENE(1:1:1))
- 1547084-84-3(2-fluoro-2-(pyridin-3-yl)ethan-1-amine)
- 1211540-26-9(5-(1,1-Difluoroethyl)pyridin-3-amine)
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- 1186194-56-8(3-(1,1-Difluoropropyl)-pyridine)
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