Cas no 114305-99-6 (1H-Indol-3-ol,6-chloro-, 3-acetate)

Technical Introduction: 1H-Indol-3-ol,6-chloro-, 3-acetate is a chemically modified indole derivative characterized by the presence of a chloro substituent at the 6-position and an acetyl group at the 3-hydroxy position. This structural modification enhances its stability and reactivity, making it a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. The chloro group contributes to electrophilic substitution selectivity, while the acetate moiety improves solubility and facilitates further functionalization. Its well-defined purity and consistent performance make it suitable for research and industrial applications requiring precise control over indole-based transformations.
1H-Indol-3-ol,6-chloro-, 3-acetate structure
114305-99-6 structure
Product Name:1H-Indol-3-ol,6-chloro-, 3-acetate
CAS No:114305-99-6
MF:C10H8ClNO2
MW:209.629021644592
CID:139307
PubChem ID:18955884
Update Time:2025-10-28

1H-Indol-3-ol,6-chloro-, 3-acetate Chemical and Physical Properties

Names and Identifiers

    • 1H-Indol-3-ol,6-chloro-, 3-acetate
    • (6-chloro-1H-indol-3-yl) acetate
    • 6-CHLORO-3-INDOLYL ACETATE
    • 6-CHLORO-3-INDOXYL-3-ACETATE
    • BIC1358
    • SALMON(TM)-ACETATE
    • RARECHEM AH BS 0026
    • 6-CHLORO-1H-INDOL-3-YL ACETATE
    • ACETIC ACID 6-CHLORO-1H-INDOL-3-YL ESTER
    • 1H-Indol-3-ol, 6-chloro-, 3-acetate
    • C-4758
    • CS-0441198
    • 1H-Indol-3-ol,6-chloro-,3-acetate
    • FD10409
    • A849958
    • AMY41431
    • AKOS015914574
    • SCHEMBL1614860
    • MFCD00269776
    • DTXSID50596842
    • 114305-99-6
    • FT-0739936
    • DB-060603
    • MDL: MFCD00269776
    • Inchi: 1S/C10H8ClNO2/c1-6(13)14-10-5-12-9-4-7(11)2-3-8(9)10/h2-5,12H,1H3
    • InChI Key: IPTGFPYPSDDUBV-UHFFFAOYSA-N
    • SMILES: ClC1C=CC2C(=CNC=2C=1)OC(C)=O

Computed Properties

  • Exact Mass: 209.02400
  • Monoisotopic Mass: 209.0243562g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 234
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.6
  • Topological Polar Surface Area: 42.1?2

Experimental Properties

  • PSA: 42.09000
  • LogP: 2.74660

1H-Indol-3-ol,6-chloro-, 3-acetate Pricemore >>

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Additional information on 1H-Indol-3-ol,6-chloro-, 3-acetate

Comprehensive Guide to 1H-Indol-3-ol,6-chloro-, 3-acetate (CAS No. 114305-99-6): Properties, Applications, and Market Insights

1H-Indol-3-ol,6-chloro-, 3-acetate (CAS No. 114305-99-6) is a specialized indole derivative that has garnered significant attention in pharmaceutical and biochemical research. This compound, characterized by its unique chloro-substituted indole structure, serves as a critical intermediate in the synthesis of bioactive molecules. Researchers and industry professionals frequently search for 6-chloroindole derivatives due to their relevance in drug development and organic synthesis. In this article, we delve into the compound’s properties, applications, and emerging trends, addressing common queries such as "What is the role of 1H-Indol-3-ol,6-chloro-, 3-acetate in medicinal chemistry?" and "How is CAS 114305-99-6 synthesized?".

The molecular structure of 1H-Indol-3-ol,6-chloro-, 3-acetate features a chloro group at the 6-position and an acetate moiety at the 3-position of the indole ring. This configuration enhances its reactivity, making it a valuable precursor for heterocyclic compounds. Recent studies highlight its potential in designing serotonin receptor modulators, a hot topic in neuroscience research. With increasing interest in neuroactive compounds, this derivative is often discussed in forums and publications exploring CNS drug discovery.

Applications of CAS 114305-99-6 extend beyond pharmaceuticals. It is also utilized in agrochemical research for developing plant growth regulators and eco-friendly pesticides. A trending search among chemists is "sustainable synthesis of 6-chloroindole-3-acetate," reflecting the demand for greener methodologies. Additionally, its role in fluorescence labeling has been explored, aligning with the growing focus on bioimaging technologies.

The market for indole-based intermediates like 1H-Indol-3-ol,6-chloro-, 3-acetate is expanding, driven by advancements in precision medicine and biocatalysis. Analysts note a surge in patents involving chloro-substituted indoles, particularly in oncology and neurology. For suppliers and buyers, understanding purity standards (e.g., HPLC ≥98%) and storage conditions (e.g., -20°C, inert atmosphere) is crucial, as these factors dominate procurement-related searches.

In conclusion, 1H-Indol-3-ol,6-chloro-, 3-acetate (CAS No. 114305-99-6) stands at the intersection of innovation and utility. Its versatility in drug design, agricultural chemistry, and material science ensures its relevance in contemporary research. By addressing key questions like "Where to buy high-purity 6-chloroindole-3-acetate?" and "What are the latest synthetic routes?", this guide aims to serve as a trusted resource for professionals navigating the dynamic landscape of specialty chemicals.

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