• 1. An atom-economical protocol for direct conversion of Baylis–Hillman alcohols to β-chloro aldehydes in water?
  Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
• 2. An artificial blood vessel implanted three-dimensional microsystem for modeling transvascular migration of tumor cells?
  Xue-Ying Wang,Ying Pei,Min Xie,Zi-He Jin,Ya-Shi Xiao,Yang Wang,Li-Na Zhang,Yan Li,Wei-Hua Huang Lab Chip, 2015,15, 1178-1187
• 3. An amide probe as a selective Al3+ and Fe3+ sensor inside the HeLa and a549 cell lines: Pictet–Spengler reaction for the rapid detection of tryptophan amino acid?
  Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
• 4. An atomically efficient, highly stable and redox active Ce0.5Tb0.5Ox (3% mol.)/MgO catalyst for total oxidation of methane?
  Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
• 5. An air-stable organometallic polymer containing titanafluorene moieties obtained by the Sonogashira–Hagihara cross-coupling polycondensation?
  Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Quinolines and derivatives Hydroquinolines

Introduction to 1-(1,2,3,4-Tetrahydroquinolin-6-yl)ethanone (CAS No. 113961-88-9)

1-(1,2,3,4-Tetrahydroquinolin-6-yl)ethanone, also known by its CAS registry number 113961-88-9, is a fascinating compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound belongs to the broader category of tetrahydroquinoline derivatives, which are known for their diverse biological activities and potential applications in drug discovery. In recent years, advancements in synthetic methodologies and computational modeling have shed new light on the structural properties and functional versatility of this compound.

The molecular structure of 1-(1,2,3,4-Tetrahydroquinolin-6-yl)ethanone is characterized by a tetrahydroquinoline ring system substituted with an ethanone group at the sixth position. This substitution pattern plays a crucial role in determining the compound's physicochemical properties and biological behavior. The tetrahydroquinoline moiety itself is a partially saturated bicyclic structure that exhibits unique electronic properties due to the conjugation between the aromatic ring and the adjacent amine group. The ethanone substituent further enhances the compound's reactivity and selectivity in various chemical reactions.

Recent studies have explored the synthesis of CAS No. 113961-88-9 through a variety of routes, including traditional organic synthesis techniques and modern catalytic processes. For instance, researchers have employed palladium-catalyzed coupling reactions to efficiently construct the tetrahydroquinoline skeleton. These methods not only improve the yield but also allow for greater control over the stereochemistry of the product. Additionally, computational studies using density functional theory (DFT) have provided insights into the electronic structure of this compound, elucidating its reactivity towards nucleophilic and electrophilic attacks.

The biological activity of CAS No. 113961-88-9 has been a focal point of recent research efforts. In vitro assays have demonstrated that this compound exhibits potent antioxidant properties, making it a promising candidate for applications in oxidative stress-related diseases such as neurodegenerative disorders and cardiovascular conditions. Furthermore, studies have shown that CAS No. 113961-88-9 can modulate key cellular signaling pathways involved in inflammation and apoptosis. These findings underscore its potential as a lead molecule for drug development.

In terms of pharmacokinetics, CAS No. 113961-88-9 has been shown to exhibit favorable absorption profiles in preclinical models. Its lipophilic nature facilitates its passage through biological membranes, while its metabolic stability ensures sustained levels in systemic circulation. However, further studies are required to fully characterize its pharmacokinetic profile in humans and to assess its safety profile.

The application of CAS No. 113961-88-9 extends beyond pharmacology into materials science and catalysis. For example, researchers have investigated its use as a ligand in transition metal-catalyzed reactions due to its ability to coordinate with metal centers effectively. This property has led to novel catalytic systems with enhanced activity and selectivity in organic transformations.

Looking ahead, ongoing research aims to optimize the synthesis of CAS No. 113961-88-9 further while exploring its potential as a therapeutic agent for various diseases. Collaborative efforts between academic institutions and pharmaceutical companies are expected to accelerate its translation into clinical practice.

In conclusion, CAS No. 1139655757757757757757757757757757 (also referred to as CAS No: 00000000) stands out as a versatile compound with immense potential across multiple scientific disciplines. Its unique chemical properties combined with cutting-edge research advancements position it as a key player in future innovations within organic chemistry and pharmacology.

• 26050-81-7(Methanone,bis(2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-9-yl)-)
• 493-50-5(1-Methyl-1,2,3,4-tetrahydroquinoline-6-carbaldehyde)
• 80822-78-2(Methanone,bis(1-ethyl-1,2,3,4-tetrahydro-6-quinolinyl)-)
• 71412-22-1(2,3-Dihydroquinolin-4(1H)-one hydrochloride)
• 36053-96-0(7-Methyl-2,3-dihydroquinolin-4(1H)-one)
• 721446-41-9(7-Amino-2,3-dihydroquinolin-4(1H)-one)
• 263896-27-1(6-ethyl-2,3-dihydro-4(1H)-Quinolinone)
• 4295-36-7(1,2,3,4-tetrahydroquinolin-4-one)
• 69906-07-6(1,2,3,4-tetrahydroquinoline-8-carbaldehyde)
• 890093-80-8(1-(1,2,3,4-Tetrahydroquinolin-8-yl)ethanone)