• 1. Aromatic rearrangements in the benzene series. Part 3. Rearrangement of isotopically labelled phenyl benzoates: intermolecularity of the ortho-directed rearrangement. Criteria for determining the intra-/inter-molecularity of aromatic rearrangements
  Ian M. Dawson,Lionel S. Hart,John S. Littler J. Chem. Soc. Perkin Trans. 2 1985 1601
• 2. CCCLXXXIII.—Substitution products of 4-hydroxybenzophenone and of its methyl ether
  William Blakey,Walter Idris Jones,Harold Archibald Scarborough J. Chem. Soc. 1927 2865
• 3. An approach to polymer-supported triplet benzophenone photocatalysts. Application to sustainable photocatalysis of an α-diazocarbonyl compound
  Lourdes Pastor-Pérez,Carla Lloret-Fernández,Hafid Anane,Moulay Lahcen El Idrissi Moubtassim,Miguel Julve,Salah-Eddine Stiriba RSC Adv. 2013 3 25652
• 4. Primary photochemical processes in aromatic molecules. Part 10.—Photochemistry of substituted benzophenones
  A. Beckett,G. Porter Trans. Faraday Soc. 1963 59 2051
• 5. Photochemical processes induced by the irradiation of 4-hydroxybenzophenone in different solvents
  Francesco Barsotti,Marcello Brigante,Mohamed Sarakha,Valter Maurino,Claudio Minero,Davide Vione Photochem. Photobiol. Sci. 2015 14 2087

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzophenones
• Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone

4-Hydroxybenzophenone (CAS 1137-42-4): Properties, Applications, and Industry Insights

4-Hydroxybenzophenone (CAS 1137-42-4), also known as p-hydroxybenzophenone or benzophenone-4, is a versatile organic compound with significant applications in various industries. This hydroxybenzophenone derivative has gained attention due to its unique chemical properties and wide-ranging uses, particularly in the fields of UV protection, polymer stabilization, and pharmaceutical intermediates.

The molecular structure of 4-Hydroxybenzophenone features a benzophenone core with a hydroxyl group at the para position, giving it distinct photochemical characteristics. This structural feature makes it particularly valuable as a UV absorber in numerous applications. Recent interest in this compound has grown alongside increasing consumer awareness about sun protection and material durability, topics that frequently appear in search engine queries related to cosmetic ingredients and polymer additives.

In the cosmetics industry, 4-Hydroxybenzophenone serves as an effective sunscreen agent, absorbing UV radiation in the 280-320 nm range. Its ability to protect skin from harmful UV-B rays while maintaining good solubility in cosmetic formulations has made it a popular choice among product developers. Current market trends show growing demand for multifunctional cosmetic ingredients, and this compound fits well within this category by offering both UV protection and formulation stability.

The plastics and coatings industry utilizes 4-Hydroxybenzophenone as a light stabilizer to prevent polymer degradation caused by ultraviolet radiation. With increasing emphasis on sustainable materials and longer product lifespans - frequently searched terms in material science forums - the importance of effective UV stabilizers like 4-Hydroxybenzophenone continues to rise. Its compatibility with various polymers makes it particularly valuable for outdoor applications where weather resistance is crucial.

From a chemical perspective, 4-Hydroxybenzophenone demonstrates interesting properties that make it useful in organic synthesis. The compound serves as a building block for more complex molecules, particularly in pharmaceutical research where modified benzophenone derivatives often exhibit biological activity. The presence of both hydroxyl and carbonyl functional groups allows for diverse chemical modifications, making it a valuable intermediate in medicinal chemistry.

The production and purification of 4-Hydroxybenzophenone involve specialized processes to ensure high purity levels required for sensitive applications like cosmetics and pharmaceuticals. Manufacturers employ various analytical techniques, including HPLC and spectroscopic methods, to verify the compound's quality and consistency. These quality control measures address common industry concerns about ingredient purity and batch-to-batch consistency, topics that frequently appear in supplier evaluation criteria.

Market analysis indicates steady growth for 4-Hydroxybenzophenone applications, particularly in Asia-Pacific regions where cosmetics production and polymer manufacturing are expanding rapidly. Industry reports suggest increasing interest in multifunctional additives that can serve multiple purposes in formulations, a trend that favors compounds like 4-Hydroxybenzophenone with its dual functionality as both UV absorber and stabilizer.

Environmental and regulatory aspects of 4-Hydroxybenzophenone use have become important discussion points, particularly in cosmetic applications. The compound has been evaluated by various regulatory bodies for safety in personal care products, with most concluding its safe use at approved concentrations. This regulatory status makes it a reliable choice for formulators needing approved UV filter ingredients, addressing common formulator concerns about regulatory compliance and consumer safety.

Recent research has explored potential new applications for 4-Hydroxybenzophenone derivatives in advanced materials and specialty chemicals. Some studies investigate its use in photoresist materials for electronics manufacturing or as a component in advanced coating systems. These emerging applications demonstrate the compound's versatility beyond traditional uses, aligning with industry searches for innovative chemical solutions and performance materials.

For researchers and industry professionals working with 4-Hydroxybenzophenone, proper handling and storage recommendations include protection from light and moisture to maintain stability. While not classified as hazardous under standard regulations, standard laboratory precautions for handling organic compounds should be observed. These practical considerations address common queries from new users about chemical storage and material handling best practices.

The future outlook for 4-Hydroxybenzophenone appears positive, with potential growth in both established and emerging applications. As industries continue to demand high-performance additives and multifunctional ingredients, this compound's unique combination of properties positions it well to meet these needs. Ongoing research into modified hydroxybenzophenone derivatives may further expand its utility in specialized applications, making it a compound worth watching in chemical innovation circles.

• 121-71-1(3'-Hydroxyacetophenone)
• 15517-46-1(Methanone,1,1'-(1,4-phenylene)bis[1-(4-hydroxyphenyl)-)
• 52222-87-4(Methanone,(6-hydroxy-2-naphthalenyl)phenyl-)
• 87533-51-5(Ethanone, 1,1'-(5-hydroxy-1,3-phenylene)bis-)
• 71372-37-7(Methanone, (4-hydroxyphenyl)(3-methylphenyl)-)
• 13020-57-0(3-Hydroxybenzophenone)
• 99-93-4(1-(4-Hydroxyphenyl)ethanone)
• 62810-49-5(Methanone, (3-hydroxyphenyl)(4-methylphenyl)-)
• 611-99-4(Bis(4-hydroxy)benzophenone)
• 611-81-4(Methanone, (3-hydroxyphenyl)(4-hydroxyphenyl)-)