Cas no 1134328-00-9 (6-(benzyloxy)-2-methylpyridin-3-amine)

6-(Benzyloxy)-2-methylpyridin-3-amine is a pyridine derivative featuring a benzyloxy substituent at the 6-position and an amino group at the 3-position. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of both the benzyloxy and amino functional groups enhances its reactivity, enabling selective modifications for the construction of complex heterocyclic frameworks. Its stable crystalline form ensures ease of handling and storage. The compound’s structural features make it valuable for applications in medicinal chemistry, where it can be utilized as a building block for biologically active molecules, including kinase inhibitors and other therapeutic agents.
6-(benzyloxy)-2-methylpyridin-3-amine structure
1134328-00-9 structure
Product Name:6-(benzyloxy)-2-methylpyridin-3-amine
CAS No:1134328-00-9
MF:C13H14N2O
MW:214.263062953949
MDL:MFCD11858520
CID:1201444
PubChem ID:53408371
Update Time:2025-05-19

6-(benzyloxy)-2-methylpyridin-3-amine Chemical and Physical Properties

Names and Identifiers

    • 6-(Benzyloxy)-2-methyl-3-pyridinamine
    • 6-Benzyloxy-2-methyl-pyridin-3-ylamine
    • 6-(benzyloxy)-2-methylpyridin-3-amine
    • 3-Pyridinamine, 2-methyl-6-(phenylmethoxy)-
    • 2-methyl-6-phenylmethoxypyridin-3-amine
    • SB30790
    • CS-0441278
    • SCHEMBL23274021
    • EN300-1295432
    • AKOS017561354
    • 1134328-00-9
    • MDL: MFCD11858520
    • Inchi: 1S/C13H14N2O/c1-10-12(14)7-8-13(15-10)16-9-11-5-3-2-4-6-11/h2-8H,9,14H2,1H3
    • InChI Key: CSVUNRXYGAQHJU-UHFFFAOYSA-N
    • SMILES: O(C1C=CC(=C(C)N=1)N)CC1C=CC=CC=1

Computed Properties

  • Exact Mass: 214.110613074g/mol
  • Monoisotopic Mass: 214.110613074g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 204
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.7
  • Topological Polar Surface Area: 48.1?2

Experimental Properties

  • Density: 1.152

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Additional information on 6-(benzyloxy)-2-methylpyridin-3-amine

6-(Benzyloxy)-2-Methylpyridin-3-Amine: A Comprehensive Overview

6-(Benzyloxy)-2-Methylpyridin-3-Amine (CAS No. 1134328-00-9) is a fascinating compound that has garnered significant attention in the fields of organic chemistry and pharmacology. This compound, characterized by its unique structure, has been the subject of extensive research due to its potential applications in drug development and material science. In this article, we will delve into the properties, synthesis, and recent advancements associated with 6-(Benzyloxy)-2-Methylpyridin-3-Amine, providing a comprehensive understanding of its significance in modern scientific research.

The molecular structure of 6-(Benzyloxy)-2-Methylpyridin-3-Amine consists of a pyridine ring substituted with a benzyloxy group at position 6, a methyl group at position 2, and an amine group at position 3. This arrangement imparts the compound with unique electronic and steric properties, making it an ideal candidate for various chemical reactions. Recent studies have highlighted its role as an intermediate in the synthesis of bioactive molecules, particularly in the development of novel pharmaceutical agents.

One of the most notable aspects of 6-(Benzyloxy)-2-Methylpyridin-3-Amine is its versatility in synthetic chemistry. Researchers have employed this compound as a key intermediate in the construction of complex heterocyclic frameworks. For instance, its ability to undergo nucleophilic aromatic substitution reactions has been exploited to synthesize a wide range of pyridine derivatives with diverse functional groups. These derivatives have shown promise in fields such as oncology, where they exhibit potential anti-tumor activity.

In addition to its synthetic applications, 6-(Benzyloxy)-2-Methylpyridin-3-Amine has also been investigated for its pharmacological properties. Recent studies have demonstrated that this compound exhibits significant anti-inflammatory and antioxidant effects, making it a potential candidate for the development of novel therapeutic agents. Furthermore, its ability to modulate cellular signaling pathways has been explored in the context of neurodegenerative diseases, offering new avenues for drug discovery.

The synthesis of 6-(Benzyloxy)-2-Methylpyridin-3-Amine involves a multi-step process that typically begins with the preparation of intermediates such as benzyl bromide and pyridine derivatives. The reaction sequence often includes nucleophilic substitution, oxidation, and reduction steps, each carefully optimized to ensure high yields and purity. Recent advancements in catalytic methods have further enhanced the efficiency of these reactions, enabling large-scale production for both academic and industrial purposes.

From an environmental standpoint, 6-(Benzyloxy)-2-Methylpyridin-3-Amine has been studied for its biodegradability and ecological impact. Research indicates that under specific conditions, this compound can undergo microbial degradation, reducing its persistence in the environment. This finding is particularly important for industries involved in chemical manufacturing, as it underscores the need for sustainable practices to minimize ecological footprint.

In conclusion, 6-(Benzyloxy)-2-Methylpyridin-3-Amine (CAS No. 1134328-00-9) stands as a testament to the ingenuity of modern chemistry. Its unique structure, versatile reactivity, and promising pharmacological properties make it a valuable asset in both academic research and industrial applications. As ongoing studies continue to uncover new insights into its potential uses, this compound is poised to play an increasingly significant role in shaping the future of drug discovery and materials science.

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