• 1. Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines?
  Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
• 2. Enantiomeric two-fold interpenetrated 3D zinc(ii) coordination networks as a catalytic platform: significant difference between water within the cage and trace water in transesterification?
  Eunkyung Choi,Minjoo Ryu,Haeri Lee,Ok-Sang Jung Dalton Trans., 2017,46, 4595-4601
• 3. Enabling stable MnO2 matrix for aqueous zinc-ion battery cathodes?
  Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
• 4. Fe3O4 nanosphere@microporous organic networks: enhanced anode performances in lithium ion batteries through carbonization?
  Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
• 5. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
  Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Piperidines Phenylpiperidines

Comprehensive Overview of Ethyl 5-iodo-2-(piperidin-1-yl)benzoate (CAS No. 1131622-44-0)

Ethyl 5-iodo-2-(piperidin-1-yl)benzoate (CAS No. 1131622-44-0) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. This compound belongs to the class of iodinated benzoate derivatives, which are widely studied for their potential applications in drug discovery and material science. The presence of both piperidine and iodo functional groups in its structure makes it a versatile intermediate for synthesizing more complex molecules.

In recent years, the demand for highly functionalized benzoate esters like Ethyl 5-iodo-2-(piperidin-1-yl)benzoate has increased due to their role in developing novel therapeutic agents. Researchers are particularly interested in its potential as a building block for kinase inhibitors and GPCR-targeted drugs, which are hot topics in modern medicinal chemistry. The compound's unique structure allows for further modifications, enabling the creation of libraries of derivatives for high-throughput screening.

The synthesis of Ethyl 5-iodo-2-(piperidin-1-yl)benzoate typically involves multi-step organic reactions, including iodination and esterification processes. Its CAS No. 1131622-44-0 serves as a unique identifier in chemical databases, making it easier for researchers to track its properties and applications. The compound's molecular weight, solubility, and stability data are crucial for those working in pharmaceutical formulation and process chemistry.

From an industrial perspective, Ethyl 5-iodo-2-(piperidin-1-yl)benzoate is often discussed in the context of green chemistry and sustainable synthesis. Many users search for information about eco-friendly production methods for such compounds, reflecting the growing emphasis on environmental responsibility in chemical manufacturing. The compound's potential applications in bioconjugation and proteomics research also make it relevant to current trends in precision medicine and diagnostic development.

Quality control is another critical aspect when working with Ethyl 5-iodo-2-(piperidin-1-yl)benzoate. Analytical techniques such as HPLC, NMR, and mass spectrometry are essential for verifying its purity and structure. These methods are frequently searched by quality assurance professionals and researchers who need to characterize the compound accurately. The availability of high-purity grades and custom synthesis options for this material is often a point of interest for procurement specialists.

In the context of intellectual property, CAS No. 1131622-44-0 appears in numerous patent applications related to heterocyclic chemistry and medicinal compounds. This highlights its importance in proprietary research and development efforts. The compound's structural features make it valuable for creating patentable novel chemical entities, which is a key consideration for pharmaceutical companies investing in new drug pipelines.

Looking ahead, the scientific community continues to explore new applications for Ethyl 5-iodo-2-(piperidin-1-yl)benzoate in emerging fields such as chemical biology and materials science. Its potential use in developing fluorescent probes and molecular sensors represents an exciting frontier for research. As synthetic methodologies advance, we can expect to see more efficient routes to this compound and its derivatives, addressing the needs of both academic and industrial researchers.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)