• 1. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 2. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
• 3. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
  Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
• 4. Examination of the hydrogen-bonding networks in small water clusters (n = 2–5, 13, 17) using absolutely localized molecular orbital energy decomposition analysis?
  Erika A. Cobar,Paul R. Horn,Robert G. Bergman,Martin Head-Gordon Phys. Chem. Chem. Phys., 2012,14, 15328-15339
• 5. Fate of nitrogen-15 in the subsequent growing season of greenhouse tomato plants (Lycopersicon esculentum Mill) as influenced by alternate partial root-zone irrigation
  Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400

2-Chloro-6-fluoro-3-formylbenzoic Acid: A Comprehensive Overview

The compound with CAS No. 1131605-23-6, known as 2-Chloro-6-fluoro-3-formylbenzoic acid, is a significant molecule in the field of organic chemistry and pharmacology. This compound has garnered attention due to its unique structural properties and potential applications in drug development. The molecule consists of a benzoic acid backbone with substituents at positions 2, 3, and 6, specifically a chlorine atom, a formyl group, and a fluorine atom, respectively. These substituents contribute to its distinct chemical reactivity and biological activity.

Recent studies have highlighted the importance of 2-Chloro-6-fluoro-3-formylbenzoic acid in the development of novel therapeutic agents. Researchers have explored its role as a precursor in the synthesis of bioactive compounds, particularly in the context of anti-inflammatory and anticancer drug design. The presence of the formyl group at position 3 introduces versatility in chemical modifications, enabling the creation of derivatives with enhanced pharmacokinetic profiles.

One notable area of research involves the evaluation of 2-Chloro-6-fluoro-3-formylbenzoic acid as a potential lead compound for targeting specific cellular pathways. For instance, studies have demonstrated its ability to modulate enzymes involved in inflammation, such as cyclooxygenase (COX) and lipoxygenase (LOX). These findings suggest that the compound could serve as a foundation for developing safer and more effective anti-inflammatory agents compared to existing therapies.

In addition to its pharmacological applications, 2-Chloro-6-fluoro-3-formylbenzoic acid has also been investigated for its role in materials science. The molecule's aromatic structure and functional groups make it a candidate for use in the synthesis of advanced materials, such as organic semiconductors and sensors. Researchers have explored its electronic properties, which could be harnessed for applications in flexible electronics and optoelectronic devices.

The synthesis of 2-Chloro-6-fluoro-3-formylbenzoic acid involves multi-step organic reactions that require precise control over reaction conditions. Key steps include Friedel-Crafts alkylation for introducing substituents onto the aromatic ring and subsequent oxidation reactions to install the formyl group. Recent advancements in catalytic methods have improved the efficiency and selectivity of these reactions, making large-scale production more feasible.

From an environmental perspective, understanding the degradation pathways of 2-Chloro-6-fluoro-3-formylbenzoic acid is crucial for assessing its ecological impact. Studies have shown that the compound undergoes microbial degradation under aerobic conditions, with key intermediates being identified through metabolomics analysis. This information is essential for ensuring sustainable practices in its production and disposal.

Looking ahead, the potential applications of 2-Chloro-6-fluoro-3-formylbenzoic acid are vast and varied. Its role as a versatile building block in organic synthesis positions it as a valuable asset in both academic research and industrial development. As research continues to uncover new properties and functions of this compound, it is likely to play an increasingly important role in advancing science and technology.

• 4122-27-4(6-chloro-2-fluoro-3-methylbenzoic Acid)
• 904285-09-2(2,4-Dichloro-6-fluorobenzoic acid)
• 32890-89-4(2-Chloro-6-fluoro-3-methylbenzoic acid)
• 173315-54-3(2-chloro-4-fluoro-3-methylbenzoic Acid)
• 434-75-3(2-chloro-6-fluoro-benzoic acid)
• 32890-91-8(2,3-Dichloro-6-fluorobenzoic acid)
• 32890-90-7(6-Chloro-2-fluoro-3-methylbenzoic acid)
• 287172-74-1(2-Chloro-3,6-difluorobenzoic acid)
• 916420-62-7(3,6-Dichloro-2-fluorobenzoic acid)
• 1242339-67-8(2-CHLORO-4,6-DIFLUOROBENZOIC ACID)