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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acid esters
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acid esters

Comprehensive Analysis of Methyl 4-ethoxy-3-iodobenzoate (CAS No. 1131588-13-0): Properties, Applications, and Industry Trends

Methyl 4-ethoxy-3-iodobenzoate (CAS No. 1131588-13-0) is a specialized organic compound widely recognized in pharmaceutical and agrochemical research. Its molecular structure, featuring an ethoxy group and an iodo substituent on a benzoate backbone, makes it a versatile intermediate for synthesizing complex molecules. This compound’s unique properties, such as its stability under mild conditions and reactivity in cross-coupling reactions, have garnered significant attention from researchers exploring drug discovery and material science applications.

In recent years, the demand for iodinated aromatic compounds like Methyl 4-ethoxy-3-iodobenzoate has surged due to their role in palladium-catalyzed reactions, a hotspot in modern organic chemistry. Searches for "Suzuki-Miyaura coupling" and "iodoarene derivatives" have spiked, reflecting industry interest in efficient synthetic pathways. This compound’s compatibility with green chemistry principles—such as reduced waste and energy-efficient protocols—aligns with global sustainability trends, further driving its adoption.

The pharmaceutical industry leverages Methyl 4-ethoxy-3-iodobenzoate as a building block for active pharmaceutical ingredients (APIs). Its electron-withdrawing and steric effects enhance molecular diversity in drug design, addressing challenges like bioavailability and target selectivity. Researchers frequently inquire about "high-yield synthesis of iodobenzoates" or "applications in medicinal chemistry," underscoring its relevance in cutting-edge studies.

From a commercial perspective, CAS No. 1131588-13-0 is supplied by leading fine chemical manufacturers with stringent purity standards (>98%). Analytical techniques like HPLC and NMR spectroscopy ensure quality control, meeting the needs of contract research organizations (CROs) and academic labs. Discussions on "scalable synthesis routes" and "cost-effective iodination methods" dominate forums, highlighting practical considerations for industrial use.

Looking ahead, innovations in catalytic processes and heterocyclic chemistry are expected to expand the utility of Methyl 4-ethoxy-3-iodobenzoate. Its integration into high-throughput screening platforms and combinatorial libraries positions it as a key player in next-generation therapeutic development. As regulatory frameworks evolve, compliance with REACH and GMP guidelines remains critical for suppliers and end-users alike.

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• 35387-92-9(Methyl 4-iodo-3-methoxybenzoate)
• 1131614-15-7(Methyl 3-iodo-4-isopropoxybenzoate)
• 1131614-40-8(Ethyl 4-acetoxy-3-iodobenzoate)
• 1131614-13-5(Methyl 3-iodo-4-propoxybenzoate)
• 4253-10-5(Methyl 3,5-diiodo-4-methoxybenzoate)
• 207115-38-6(Ethyl 3-iodo-4-methoxybenzoate)
• 741699-04-7(Ethyl 3-ethoxy-4-iodobenzoate)
• 1131614-46-4(Ethyl 3-iodo-4-propoxybenzoate)