Cas no 1125410-01-6 (5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine)

5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine is a brominated pyridine derivative featuring a cyclohexyl-methylamino substituent at the 2-position. This compound is of interest in pharmaceutical and agrochemical research due to its versatile reactivity, particularly in cross-coupling reactions facilitated by the bromine moiety. The cyclohexyl-methylamino group enhances steric and electronic properties, making it useful for modifying molecular interactions in ligand design or as an intermediate in synthetic pathways. Its stability under standard conditions and compatibility with common organic solvents further contribute to its utility in multistep syntheses. The compound’s structural features make it a valuable building block for developing biologically active molecules or functional materials.
5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine structure
1125410-01-6 structure
Product Name:5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine
CAS No:1125410-01-6
MF:C12H17BrN2
MW:269.180782079697
MDL:MFCD11844796
CID:1076156
PubChem ID:45588188
Update Time:2025-06-08

5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine Chemical and Physical Properties

Names and Identifiers

    • N-(5-Bromo-2-pyridinyl)-N-cyclohexyl-N-methylamine
    • 5-bromo-N-cyclohexyl-N-methylpyridin-2-amine
    • AKOS010631838
    • AVB41001
    • MFCD11844796
    • DTXSID60670586
    • 1125410-01-6
    • 5-BROMO-2-(N-CYCLOHEXYL-N-METHYLAMINO)PYRIDINE
    • BS-25688
    • 5-Bromo-2-(cyclohexyl-methylamino)pyridine
    • 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine
    • MDL: MFCD11844796
    • Inchi: 1S/C12H17BrN2/c1-15(11-5-3-2-4-6-11)12-8-7-10(13)9-14-12/h7-9,11H,2-6H2,1H3
    • InChI Key: KUXLHBACHKOIHP-UHFFFAOYSA-N
    • SMILES: BrC1=CN=C(C=C1)N(C)C1CCCCC1

Computed Properties

  • Exact Mass: 268.05800
  • Monoisotopic Mass: 268.05751g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 192
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.8
  • Topological Polar Surface Area: 16.1?2

Experimental Properties

  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 350.6±22.0 °C at 760 mmHg
  • Flash Point: 165.8±22.3 °C
  • PSA: 16.13000
  • LogP: 3.61300
  • Vapor Pressure: 0.0±0.8 mmHg at 25°C

5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine Security Information

5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine

5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine: An Overview of a Promising Compound (CAS No. 1125410-01-6)

5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine (CAS No. 1125410-01-6) is a versatile organic compound that has garnered significant attention in recent years due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science. This compound is characterized by its unique structure, which combines a brominated pyridine ring with a cyclohexylmethylamino substituent. This combination endows the molecule with a range of chemical and biological properties that make it an attractive candidate for further research and development.

The chemical structure of 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine is particularly noteworthy. The bromine atom at the 5-position of the pyridine ring can serve as a versatile handle for further functionalization, allowing for the synthesis of a wide array of derivatives. The cyclohexylmethylamino group, on the other hand, introduces steric and electronic effects that can influence the compound's reactivity and biological activity. These features make 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine an excellent starting material for the synthesis of more complex molecules.

In the pharmaceutical industry, 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine has shown promise as a lead compound for drug discovery. Recent studies have explored its potential as a scaffold for the development of new therapeutic agents. For instance, researchers have investigated its use in the design of inhibitors for specific enzymes involved in various diseases, such as cancer and neurodegenerative disorders. The bromine atom can be replaced with other functional groups to fine-tune the compound's pharmacological properties, making it a valuable tool in medicinal chemistry.

Beyond its pharmaceutical applications, 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine has also found use in agrochemical research. Its structural features make it suitable for the development of new pesticides and herbicides. Studies have shown that derivatives of this compound can exhibit selective toxicity towards certain pests while being relatively safe for non-target organisms. This property is crucial for developing environmentally friendly agricultural products that minimize ecological impact.

In materials science, 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine has been explored as a building block for the synthesis of functional materials with unique properties. For example, researchers have used this compound to create polymers with enhanced thermal stability and mechanical strength. These materials have potential applications in various industries, including electronics, automotive, and aerospace.

The synthetic accessibility of 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine is another factor contributing to its appeal. Several efficient synthetic routes have been developed to prepare this compound on both small and large scales. These methods typically involve multistep reactions that start from readily available starting materials and proceed under mild conditions. The ability to synthesize this compound efficiently and cost-effectively is crucial for its widespread adoption in various applications.

In terms of safety and handling, 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine should be managed with standard laboratory precautions. It is important to note that while this compound does not fall into any restricted or hazardous categories, proper personal protective equipment (PPE) should be used when handling it to ensure safety.

The future prospects for 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine are promising. Ongoing research continues to uncover new applications and derivatives of this compound, expanding its utility across multiple fields. As more studies are conducted, it is likely that additional properties and uses will be discovered, further solidifying its position as a valuable chemical entity.

In conclusion, 5-Bromo-2-(N-cyclohexyl-N-methylamino)pyridine (CAS No. 1125410-01-6) is a multifaceted compound with significant potential in pharmaceuticals, agrochemicals, and materials science. Its unique chemical structure and synthetic accessibility make it an attractive candidate for further research and development. As scientists continue to explore its properties and applications, it is expected to play an increasingly important role in advancing various scientific disciplines.

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