Cas no 111749-17-8 (Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino-)

Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino-, is a structurally unique bicyclic compound characterized by its rigid adamantane-like framework and functionalized ethanolamine side chain. The β-amino group enhances its reactivity, making it a valuable intermediate in organic synthesis, particularly for the preparation of pharmacologically active molecules or complex ligands. Its sterically constrained structure contributes to high thermal and chemical stability, while the polar functional groups improve solubility in various solvents. This compound is particularly useful in medicinal chemistry for designing rigid scaffolds with tailored stereoelectronic properties. Its synthetic versatility and stability make it suitable for applications in drug development, materials science, and catalysis.
Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino- structure
111749-17-8 structure
Product Name:Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino-
CAS No:111749-17-8
MF:C12H21NO
MW:195.301243543625
CID:5457493
Update Time:2025-05-21

Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino- Chemical and Physical Properties

Names and Identifiers

    • Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino-
    • Inchi: 1S/C12H21NO/c13-11(7-14)12-4-8-1-9(5-12)3-10(2-8)6-12/h8-11,14H,1-7,13H2
    • InChI Key: HBUUJKSRVMGCEK-UHFFFAOYSA-N
    • SMILES: C(C12CC3CC(CC(C3)C1)C2)(N)CO

Experimental Properties

  • Density: 1.142±0.06 g/cm3(Predicted)
  • Boiling Point: 338.9±15.0 °C(Predicted)
  • pka: 12.99±0.10(Predicted)

Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino- Pricemore >>

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Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino- Related Literature

Additional information on Tricyclo[3.3.1.13,7]decane-1-ethanol, β-amino-

Tricyclo[3.3.1.13,?]decane-1-ethanol, β-amino-

Tricyclo[3.3.1.13,?]decane-1-ethanol, β-amino- (CAS No: 111749-17-8) is a unique bicyclic compound with a complex structure that has garnered significant attention in the fields of organic chemistry and materials science. This compound is characterized by its tricyclic framework, which consists of three fused rings: two six-membered rings and one five-membered ring. The presence of an amino group (-NH?) at the β-position and a hydroxyl group (-OH) at the 1-position of the decane backbone makes it a versatile molecule with potential applications in drug design, catalysis, and advanced materials.

The synthesis of Tricyclo[3.3.1.13,?]decane-1-ethanol, β-amino- involves a multi-step process that typically begins with the preparation of the tricyclic core using Diels-Alder reactions or other cycloaddition techniques. The subsequent introduction of the amino and hydroxyl groups requires precise functionalization strategies to ensure the desired stereochemistry and regioselectivity. Recent advancements in asymmetric catalysis have enabled researchers to achieve high yields and enantioselectivity in the synthesis of this compound, making it more accessible for further studies.

One of the most promising applications of Tricyclo[3.3.1.13,?]decane-1-ethanol, β-amino- lies in its potential as a building block for bioactive molecules. Its rigid tricyclic structure provides an ideal scaffold for designing drugs targeting specific proteins or enzymes. For instance, researchers have explored its use in developing inhibitors for kinase enzymes, which are critical in various cellular signaling pathways associated with cancer and inflammatory diseases.

In addition to its role in drug design, this compound has also shown potential in catalytic applications due to its ability to act as a chiral ligand or catalyst in asymmetric synthesis reactions. The amino group serves as a coordinating site for metal ions, enabling the formation of stable metal complexes that can catalyze various transformations with high efficiency and selectivity.

Recent studies have also highlighted the importance of Tricyclo[3.3.1.13,?]decane-1-ethanol, β-amino-in materials science, particularly in the development of advanced polymers and nanomaterials. Its unique structure allows for the creation of cross-linked networks with exceptional mechanical properties and thermal stability, making it a candidate for high-performance materials used in aerospace and electronics industries.

The structural complexity of Tricyclo[3.3.1.13?]decane-1?ethanol, β-amino-, combined with its functional groups, offers a wide range of possibilities for chemical modification and functionalization. Researchers are actively exploring its use as a precursor for synthesizing more complex molecules with tailored properties for specific applications.

In conclusion, Tricyclo[3.31·13?]decane?1?ethanol,,β-amino is a multifaceted compound with significant potential across various scientific disciplines due to its unique structure and functional groups.

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