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Comprehensive Overview of (4-Butylphenyl)hydrazine (CAS No. 111679-54-0): Properties, Applications, and Industry Insights

(4-Butylphenyl)hydrazine (CAS No. 111679-54-0) is an organic compound belonging to the hydrazine derivatives class, characterized by its unique molecular structure featuring a butylphenyl group. This compound has garnered significant attention in pharmaceutical and agrochemical research due to its versatile reactivity and potential as a building block for synthesizing more complex molecules. The CAS number 111679-54-0 serves as a critical identifier for researchers and regulatory bodies, ensuring precise communication in scientific literature and commercial transactions.

In recent years, the demand for specialized intermediates like (4-Butylphenyl)hydrazine has surged, driven by advancements in drug discovery and material science. Search engine analytics reveal growing queries such as "hydrazine derivatives applications" and "CAS 111679-54-0 suppliers," reflecting industry interest. The compound's butylphenyl moiety enhances lipophilicity, making it valuable for designing compounds with improved membrane permeability—a hot topic in bioavailability optimization studies.

From a synthetic chemistry perspective, 111679-54-0 exhibits remarkable utility in condensation reactions and heterocycle formation. Its hydrazine functional group enables nucleophilic attacks on carbonyl compounds, facilitating the creation of pyrazoles and indoles—key scaffolds in pharmaceutical active ingredients. Laboratories frequently search for "safe handling of arylhydrazines" and "spectroscopic data for 4-butylphenylhydrazine," underscoring the need for detailed technical guidance.

The compound's physicochemical properties—including a molecular weight of 178.26 g/mol and moderate solubility in organic solvents—make it compatible with standard laboratory techniques. Chromatographic analyses of (4-Butylphenyl)hydrazine typically show strong UV absorption near 280 nm, a detail frequently queried as "UV-Vis spectrum CAS 111679-54-0." These characteristics are crucial for quality control in fine chemical manufacturing processes.

Emerging applications in material science have expanded the relevance of this compound beyond traditional chemistry. Researchers investigating "conductive polymer precursors" and "metal-organic frameworks" have explored its use as a ligand or reducing agent. The butyl chain provides steric bulk that can influence crystal packing in molecular materials—a trending subtopic in advanced material design forums.

Regulatory compliance remains a key consideration for users of 111679-54-0. While not classified as hazardous under major chemical inventories, proper storage under inert atmosphere is recommended to prevent degradation. Frequent searches for "stability of substituted hydrazines" and "4-butylphenylhydrazine SDS" indicate robust safety awareness among industrial users.

Market intelligence suggests growing procurement of (4-Butylphenyl)hydrazine by contract research organizations (CROs) engaged in fragment-based drug discovery. The compound's balanced hydrophobicity aligns with current medicinal chemistry trends favoring moderate LogP values. Analytical challenges such as "HPLC method for hydrazine derivatives" frequently appear in scientific discussion boards.

Environmental fate studies of CAS 111679-54-0 remain limited, though its structural features suggest potential biodegradability via phenyl ring oxidation—a subject warranting further research given increasing focus on green chemistry principles. This gap presents opportunities for investigators exploring "environmental impact of arylhydrazines."

In conclusion, (4-Butylphenyl)hydrazine represents a multifaceted tool for modern chemical research. Its combination of synthetic accessibility and structural modularity continues to inspire innovations across life sciences and advanced materials. As industrial and academic laboratories increasingly seek "custom hydrazine derivatives" and "specialty chemical sourcing," this compound's importance in the chemical value chain appears set for sustained growth.

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