Cas no 1105663-76-0 (2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine)
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine is a boronic ester derivative featuring a pyridine core functionalized with a 2,4-difluorophenoxy group and a pinacol boronate moiety. This compound is primarily utilized as an intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the synthesis of biaryl structures with high selectivity and efficiency. The presence of the electron-withdrawing difluorophenoxy group enhances reactivity, while the pinacol boronate ensures stability under typical handling conditions. Its well-defined structure and compatibility with diverse reaction conditions make it a valuable reagent in pharmaceutical and agrochemical research, particularly for constructing complex heterocyclic frameworks. The product is typically supplied with high purity to ensure optimal performance in synthetic applications.
1105663-76-0 structure
Product Name:2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine
CAS No:1105663-76-0
MF:C11H9BFNO3
MW:233.003466367722
MDL:MFCD22375011
CID:1037583
Update Time:2025-10-29
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine Chemical and Physical Properties
Names and Identifiers
-
- (6-(2-Fluorophenoxy)pyridin-3-yl)boronic acid
- 2-(2,4-difluoro-phenoxy)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine
- AK-95258
- ANW-74914
- CTK8C5252
- KB-208830
- 2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine
-
- MDL: MFCD22375011
- Inchi: 1S/C11H9BFNO3/c13-9-3-1-2-4-10(9)17-11-6-5-8(7-14-11)12(15)16/h1-7,15-16H
- InChI Key: NYZYBRHCAFVZTC-UHFFFAOYSA-N
- SMILES: FC1C=CC=CC=1OC1C=CC(B(O)O)=CN=1
Computed Properties
- Exact Mass: 233.06600
Experimental Properties
- PSA: 62.58000
- LogP: 0.69280
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Alichem | A029184766-5g |
(6-(2-Fluorophenoxy)pyridin-3-yl)boronic acid |
1105663-76-0 | 95% | 5g |
$805.98 | 2023-09-04 | |
| TRC | D446513-50mg |
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine |
1105663-76-0 | 50mg |
$ 70.00 | 2022-06-05 | ||
| TRC | D446513-100mg |
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine |
1105663-76-0 | 100mg |
$ 95.00 | 2022-06-05 | ||
| TRC | D446513-500mg |
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine |
1105663-76-0 | 500mg |
$ 340.00 | 2022-06-05 | ||
| Matrix Scientific | 097776-250mg |
(6-(2-Fluorophenoxy)pyridin-3-yl)boronic acid, 95+% |
1105663-76-0 | 95+% | 250mg |
$101.00 | 2023-09-10 | |
| Matrix Scientific | 097776-500mg |
(6-(2-Fluorophenoxy)pyridin-3-yl)boronic acid, 95+% |
1105663-76-0 | 95+% | 500mg |
$156.00 | 2023-09-10 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1282342-1g |
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine |
1105663-76-0 | 98% | 1g |
¥3693.00 | 2024-08-09 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1282342-5g |
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine |
1105663-76-0 | 98% | 5g |
¥12960.00 | 2024-08-09 | |
| A2B Chem LLC | AD66312-1g |
6-(2-Fluorophenoxy)pyridine-3-boronic acid |
1105663-76-0 | ≥ 98 % | 1g |
$605.00 | 2024-04-20 | |
| A2B Chem LLC | AD66312-5g |
6-(2-Fluorophenoxy)pyridine-3-boronic acid |
1105663-76-0 | ≥ 98 % | 5g |
$1939.00 | 2024-04-20 |
2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine Related Literature
-
Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
-
Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
-
Jieun Kim,Han-Saem Park,Tae-Hee Kim,Sung Yeol Kim,Hyun-Kon Song Phys. Chem. Chem. Phys., 2014,16, 5295-5300
-
P. K. Wawrzyniak,M. T. P. Beerepoot,H. J. M. de Groot,F. Buda Phys. Chem. Chem. Phys., 2011,13, 10270-10279
-
Raktani Bikshapathi,Sai Prathima Parvathaneni,Vaidya Jayathirtha Rao Green Chem., 2017,19, 4446-4450
1105663-76-0 (2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine) Related Products
- 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
- 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
- 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
- 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
- 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
- 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
- 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
- 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
- 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
- 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)
Recommended suppliers
Essenoi Fine Chemical Co., Limited
Gold Member
CN Supplier
Reagent
Shanghai Joy Biotech Ltd
Gold Member
CN Supplier
Bulk
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.
Gold Member
CN Supplier
Reagent
Jiangsu Xinsu New Materials Co., Ltd
Gold Member
CN Supplier
Bulk
上海帛亦醫(yī)藥科技有限公司
Gold Member
CN Supplier
Reagent