Cas no 110482-96-7 (Ethyl 2,2-difluoropent-4-enoate)

Ethyl 2,2-difluoropent-4-enoate is a fluorinated ester compound characterized by its difluoromethyl group and terminal alkene functionality. This structure imparts reactivity in selective transformations, making it a valuable intermediate in organic synthesis, particularly for introducing fluorine-containing motifs. The presence of both the ester and alkene groups allows for versatile derivatization, including nucleophilic substitutions, reductions, or cross-coupling reactions. The difluoromethyl moiety enhances stability and can influence the electronic properties of downstream products. Its applications include pharmaceutical and agrochemical research, where fluorinated compounds are often sought for their metabolic stability and bioavailability. The compound is typically handled under inert conditions to preserve its reactivity.
Ethyl 2,2-difluoropent-4-enoate structure
110482-96-7 structure
Product Name:Ethyl 2,2-difluoropent-4-enoate
CAS No:110482-96-7
MF:C7H10F2O2
MW:164.149909496307
MDL:MFCD09763639
CID:827485
Update Time:2025-06-12

Ethyl 2,2-difluoropent-4-enoate Chemical and Physical Properties

Names and Identifiers

    • ethyl 2,2-difluoro-4-pentenoate
    • 2,2-difluoro-4-Pentenoic acid ethyl ester
    • ethyl 2,2-difluoropent-4-enoate
    • Ethyl 2,2-difluoropentenoate
    • Ethyl 2,2-diflouro pentane-4-enoate
    • 4-Pentenoic acid, 2,2-difluoro-, ethyl ester
    • ethyl2,2-difluoropent-4-enoate
    • Ethyl2,2-Difluoro-4-pentenoate
    • YWORETBGSIWDRB-UHFFFAOYSA-N
    • RP22688
    • SY033198
    • AB0028261
    • ST24024792
    • X0318
    • AM20120640
    • Ethyl 2,2-difluoropent-4-enoate
    • MDL: MFCD09763639
    • Inchi: 1S/C7H10F2O2/c1-3-5-7(8,9)6(10)11-4-2/h3H,1,4-5H2,2H3
    • InChI Key: YWORETBGSIWDRB-UHFFFAOYSA-N
    • SMILES: FC(C(=O)OCC)(CC=C)F

Computed Properties

  • Exact Mass: 164.06500
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 5
  • Complexity: 155
  • Topological Polar Surface Area: 26.3

Experimental Properties

  • Density: 1.068
  • Boiling Point: 128 oC
  • Flash Point: 31 oC
  • PSA: 26.30000
  • LogP: 1.76090

Ethyl 2,2-difluoropent-4-enoate Customs Data

  • HS CODE:2916190090
  • Customs Data:

    China Customs Code:

    2916190090

    Overview:

    2916190090 Other unsaturated acyclic monocarboxylic acids(Including its anhydride\Acyl halide,Peroxides and peroxyacids and their derivatives).Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods).VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, Acrylic acid\Acrylates or esters shall be packaged clearly

    Regulatory conditions:

    A.Customs clearance form for Inbound Goods
    B.Customs clearance form for outbound goods

    Inspection and quarantine category:

    R.Sanitary supervision and inspection of imported food
    S.Sanitary supervision and inspection of exported food
    M.Import commodity inspection
    N.Export commodity inspection

    Summary:

    2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives.supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward).VAT:17.0%.tax rebate rate:9.0%.MFN tariff:6.5%.general tariff:30.0%

Ethyl 2,2-difluoropent-4-enoate Pricemore >>

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abcr
AB497333-5 g
Ethyl 2,2-difluoropent-4-enoate, 98%; .
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€204.10 2023-04-19
abcr
AB497333-10 g
Ethyl 2,2-difluoropent-4-enoate, 98%; .
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abcr
AB497333-25 g
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TRC
E916648-50mg
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$ 50.00 2022-06-05
TRC
E916648-100mg
Ethyl 2,2-Difluoropent-4-enoate
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$ 65.00 2022-06-05
TRC
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SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
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Ethyl 2,2-difluoropent-4-enoate Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:110482-96-7)2,2-二氟-4-戊烯酸乙酯
Order Number:LE26836838
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:59
Price ($):discuss personally

Additional information on Ethyl 2,2-difluoropent-4-enoate

Ethyl 2,2-difluoropent-4-enoate (CAS No. 110482-96-7): A Compound with Emerging Potential in Chemical and Pharmaceutical Research

Ethyl 2,2-difluoropent-4-enoate, identified by its unique chemical identifier CAS No. 110482-96-7, is a fluorinated ester that has garnered significant attention in the field of organic chemistry and pharmaceutical research. This compound, characterized by its ethyl group and the presence of two fluorine atoms at the alpha position of a pentenoate backbone, exhibits intriguing structural and functional properties that make it a valuable candidate for further exploration.

The molecular structure of Ethyl 2,2-difluoropent-4-enoate consists of a five-carbon chain with double bonds and fluorine substitutions, which contribute to its distinct reactivity and potential applications. The presence of fluorine atoms introduces electron-withdrawing effects, influencing the compound's electronic properties and making it a versatile intermediate in synthetic chemistry. This structural feature has been exploited in various research endeavors to develop novel molecules with enhanced stability and bioactivity.

In recent years, the pharmaceutical industry has shown increasing interest in fluorinated compounds due to their ability to modulate metabolic pathways and improve drug efficacy. Ethyl 2,2-difluoropent-4-enoate has been studied for its potential role in the synthesis of bioactive molecules, including those targeting neurological disorders and inflammatory conditions. The compound's unique chemical profile allows for selective modifications, enabling researchers to tailor its properties for specific therapeutic applications.

One of the most compelling aspects of Ethyl 2,2-difluoropent-4-enoate is its utility as a building block in medicinal chemistry. The combination of its reactive sites—such as the enone double bond and the ester group—provides multiple opportunities for functionalization. This flexibility has been leveraged in the development of novel heterocyclic compounds, which are known for their broad spectrum of biological activities. Researchers have utilized this compound to synthesize derivatives with potential antimicrobial, anti-inflammatory, and even anticancer properties.

The fluorine atoms in Ethyl 2,2-difluoropent-4-enoate also contribute to its stability against degradation processes that might otherwise render similar compounds ineffective. This enhanced stability is particularly important in drug development, where shelf life and bioavailability are critical factors. The compound's resistance to hydrolysis and oxidation makes it a promising candidate for long-term storage and formulation into pharmaceutical products.

Recent studies have highlighted the role of fluorinated esters in enhancing the bioavailability of therapeutic agents. The electronic effects induced by fluorine atoms can improve binding affinity to biological targets, leading to more efficient drug interactions. Ethyl 2,2-difluoropent-4-enoate has been investigated in this context, showing promise as a precursor for drugs that require precise targeting and sustained activity.

The synthesis of Ethyl 2,2-difluoropent-4-enoate involves sophisticated organic reactions that showcase the compound's synthetic utility. Advanced methodologies such as cross-coupling reactions and fluorination techniques have been employed to construct its molecular framework efficiently. These synthetic strategies not only highlight the compound's versatility but also demonstrate the advancements in synthetic organic chemistry that enable the creation of complex fluorinated molecules.

In conclusion, Ethyl 2,2-difluoropent-4-enoate (CAS No. 110482-96-7) represents a significant advancement in chemical research with potential applications across multiple disciplines. Its unique structural features and reactivity make it an invaluable tool for developing novel pharmaceuticals and specialty chemicals. As research continues to uncover new uses for this compound, it is likely to play an increasingly important role in addressing complex scientific challenges.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:110482-96-7)2,2-二氟-4-戊烯酸乙酯
LE26836838
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
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