Cas no 110464-98-7 (2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride)

2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride is a versatile heterocyclic compound with applications in pharmaceutical and agrochemical synthesis. Its pyridine core, substituted with chloro, methoxy, and dimethyl groups, provides a reactive scaffold for further functionalization. The hydrochloride salt enhances solubility and stability, facilitating handling in synthetic processes. This compound is particularly valuable as an intermediate in the development of active pharmaceutical ingredients (APIs) and specialty chemicals. Its well-defined structure and high purity make it suitable for precision reactions, including nucleophilic substitutions and cross-coupling methodologies. The presence of electron-donating and withdrawing groups allows for selective modifications, enabling tailored synthesis of target molecules.
2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride structure
110464-98-7 structure
Product Name:2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride
CAS No:110464-98-7
MF:C8H11Cl2NO
MW:208.085040330887
CID:136783
PubChem ID:44968080
Update Time:2025-05-24

2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride Chemical and Physical Properties

Names and Identifiers

    • 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride
    • 2-CHLORO-3,5-DIMETHYL-4-METHOXY PYRIDINE HYDROCHLORIDE
    • Pyridine,2-chloro-4-methoxy-3,5-dimethyl-
    • PYRIDINE,2-CHLORO-4-METHOXY-3,5-DIMETHYL
    • Chloro dimethyl methoxy pyridine hydrochloride
    • 2-chloro-4-methoxy-3,5-dimethylpyridine;hydrochloride
    • 110464-98-7
    • 2-chloranyl-4-methoxy-3,5-dimethyl-pyridine hydrochloride
    • FT-0642704
    • A802252
    • 2-Chloro-4-methoxy-3,5-dimethylpyridine--hydrogen chloride (1/1)
    • AC-10599
    • DTXSID30661562
    • 1159813-71-4
    • AKOS015911864
    • 2-chloro-4-methoxy-3,5-dimethylpyridinehydrochloride
    • 2-Chloro-3,5-dimethyl-4-methoxypyridine hydrochloride
    • DB-040923
    • Inchi: 1S/C8H10ClNO.ClH/c1-5-4-10-8(9)6(2)7(5)11-3;/h4H,1-3H3;1H
    • InChI Key: NIZFMEYAXQCDSL-UHFFFAOYSA-N
    • SMILES: ClC1C(C)=C(C(C)=CN=1)OC.Cl

Computed Properties

  • Exact Mass: 207.02200
  • Monoisotopic Mass: 207.022
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 1
  • Complexity: 131
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 22.1A^2

Experimental Properties

  • Density: 1.135
  • Boiling Point: 250.1°Cat760mmHg
  • Flash Point: 105.1°C
  • Refractive Index: 1.514
  • PSA: 22.12000
  • LogP: 3.16240

2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride Pricemore >>

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Additional information on 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride

Introduction to 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride (CAS No. 110464-98-7)

2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride is a significant compound in the realm of pharmaceutical and chemical research, characterized by its unique structural and functional properties. This compound, identified by the Chemical Abstracts Service Number (CAS No.) 110464-98-7, has garnered attention due to its versatile applications in the synthesis of bioactive molecules and its role in advancing drug discovery initiatives.

The molecular structure of 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride consists of a pyridine core substituted with chloro, methoxy, and dimethyl groups at specific positions. This arrangement imparts distinct reactivity and binding capabilities, making it a valuable intermediate in the construction of complex organic molecules. The hydrochloride salt form enhances its solubility in polar solvents, facilitating its use in various synthetic protocols.

In recent years, 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride has been extensively studied for its potential in medicinal chemistry. Researchers have leveraged its scaffold to develop novel therapeutic agents targeting a range of diseases. One notable area of exploration is its application in the synthesis of kinase inhibitors, where the pyridine moiety serves as a key pharmacophore for interactions with biological targets.

Recent advancements in computational chemistry have further highlighted the significance of 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride. Molecular modeling studies indicate that this compound can modulate protein-protein interactions by binding to specific pockets on target enzymes. Such insights have guided the design of more potent and selective inhibitors, contributing to the development of next-generation drugs with improved efficacy and reduced side effects.

The pharmaceutical industry has also been keen on exploring the applications of 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride in the synthesis of antiviral and anticancer agents. Its structural features allow for modifications that enhance binding affinity to viral proteases and kinases involved in cancer progression. Preliminary clinical trials have demonstrated promising results when this compound is incorporated into drug regimens targeting these diseases.

From a synthetic chemistry perspective, 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride serves as a versatile building block for constructing more complex heterocyclic compounds. Its reactivity with nucleophiles and electrophiles enables the formation of diverse functional groups, making it an indispensable tool in synthetic laboratories. The development of novel synthetic routes to this compound has further streamlined its production, ensuring a steady supply for research and industrial applications.

The environmental impact of synthesizing and handling 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride is another critical consideration. Efforts have been made to optimize synthetic pathways to minimize waste and reduce energy consumption. Green chemistry principles have been integrated into production processes, ensuring that the compound is manufactured sustainably while maintaining high purity standards.

In conclusion, 2-Chloro-4-methoxy-3,5-dimethylpyridine hydrochloride (CAS No. 110464-98-7) represents a cornerstone in modern pharmaceutical research. Its unique structural features and reactivity make it an invaluable asset in drug discovery programs targeting various diseases. As research continues to uncover new applications for this compound, its importance in advancing medical science is undeniable.

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