Cas no 11033-64-0 ((+)-N-Deacetyllappaconitine)

(+)-N-Deacetyllappaconitine is a diterpenoid alkaloid derived from the Aconitum species, known for its potential pharmacological properties. This compound is of interest due to its structural relationship to lappaconitine, a well-studied analgesic and antiarrhythmic agent. The (+)-N-Deacetyllappaconitine variant offers researchers a purified form for studying structure-activity relationships, particularly in modulating sodium channels and exploring its biological effects. Its high purity and well-characterized structure make it suitable for analytical standards, mechanistic studies, and drug discovery applications. The compound’s stability and solubility profile further enhance its utility in experimental settings, providing a reliable tool for advancing research in neuropharmacology and natural product chemistry.
(+)-N-Deacetyllappaconitine structure
(+)-N-Deacetyllappaconitine structure
Product Name:(+)-N-Deacetyllappaconitine
CAS No:11033-64-0
MF:C30H42N2O7
MW:542.663689136505
CID:151094
Update Time:2025-05-24

(+)-N-Deacetyllappaconitine Chemical and Physical Properties

Names and Identifiers

    • Aconitane-4,8,9-triol,20-ethyl-1,14,16-trimethoxy-, 4-(2-aminobenzoate), (1a,14a,16b)-
    • N-DESACETYL LAPPACONITINE
    • 2-(4-hydroxyphenyl)ethylamine hydrochloride
    • 4-(2-Aminoethyl)phenol hydrochloride
    • 4-Hydroxyphenethylamine hydrochloride
    • 4-hydroxyphenylethylamine hydrochloride
    • CCRIS 986
    • N-deacetyllappaconitine
    • N-deacetyllappoconitine
    • picrolappaconitine
    • p-Tryamine hydrochloride
    • p-Tyramine hydrochloride
    • puberanidine
    • Tyramine HCL
    • tyramine hydrogen chloride
    • Tyramine monochloride
    • Tyrosamine hydrochloride
    • Lappaconitine, deacetyl-
    • 4-Anthraniloyllappaconine
    • DEACETYLLAPPACONITINE (N-)
    • Lappaconine, 4-(2-aminobenzoate)
    • 20-Ethyl-1α,14α,16β-trimethoxyaconitane-4,8,9-triol 4-(2-aminobenzoate)
    • N-leacetyl-lappaconitine
    • (+)-N-Deacetyllappaconitine
    • Inchi: 1S/C30H42N2O7/c1-5-32-15-27(39-26(33)16-8-6-7-9-19(16)31)11-10-23(37-3)29-21(27)13-18(24(29)32)28(34)14-20(36-2)17-12-22(29)30(28,35)25(17)38-4/h6-9,17-18,20-25,34-35H,5,10-15,31H2,1-4H3/t17-,18?,20+,21-,22+,23?,24?,25+,27-,28+,29?,30+/m1/s1
    • InChI Key: VSUODASNSRJNCP-BXUVZERWSA-N
    • SMILES: O[C@@]12[C@H]([C@H]3[C@H](C[C@@]1(C1C[C@@H]4[C@]5(CCC(C4(C1N(CC)C5)[C@@H]2C3)OC)OC(C1C=CC=CC=1N)=O)O)OC)OC

(+)-N-Deacetyllappaconitine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
D198640-1mg
(+)-N-Deacetyllappaconitine
11033-64-0
1mg
$253.00 2023-05-18
TRC
D198640-5mg
(+)-N-Deacetyllappaconitine
11033-64-0
5mg
$1016.00 2023-05-18
TRC
D198640-10mg
(+)-N-Deacetyllappaconitine
11033-64-0
10mg
$ 1800.00 2023-09-08

Additional information on (+)-N-Deacetyllappaconitine

Exploring the Pharmacological Potential of (+)-N-Deacetyllappaconitine (CAS 11033-64-0): A Comprehensive Review

In the realm of natural product chemistry, (+)-N-Deacetyllappaconitine (CAS 11033-64-0) stands out as a bioactive alkaloid derived from the Aconitum genus. This compound has garnered significant attention due to its unique structural features and potential therapeutic applications. Researchers and pharmaceutical developers are increasingly focusing on its mechanism of action, particularly in the context of neuropharmacology and anti-inflammatory effects. With the rise of interest in plant-derived therapeutics, this alkaloid exemplifies how traditional medicine can inspire modern drug discovery.

The chemical structure of (+)-N-Deacetyllappaconitine includes a diterpenoid skeleton, which is characteristic of many biologically active compounds. Its CAS number, 11033-64-0, serves as a unique identifier in chemical databases, facilitating research reproducibility. Recent studies highlight its interaction with voltage-gated sodium channels, a property shared with other alkaloids like aconitine. However, unlike its more toxic counterparts, (+)-N-Deacetyllappaconitine exhibits a favorable safety profile, making it a promising candidate for further investigation.

One of the most searched topics in pharmacognosy revolves around the bioavailability and metabolic pathways of plant alkaloids. For (+)-N-Deacetyllappaconitine, preliminary data suggest moderate oral absorption and hepatic metabolism via CYP450 enzymes. These findings align with the growing demand for natural alternatives to synthetic drugs, especially in managing chronic conditions. Online queries such as "natural pain relief compounds" or "plant-based neuroprotective agents" reflect public interest in this niche, positioning (+)-N-Deacetyllappaconitine as a relevant subject for discussion.

From a drug development perspective, the compound’s structure-activity relationship (SAR) has been a focal point. Modifications to its acetyl group or benzoyl moiety could enhance selectivity toward specific biological targets. Such insights are critical for optimizing lead compounds in preclinical stages. Additionally, the compound’s potential role in mitochondrial function modulation has sparked debates in forums discussing energy metabolism disorders, further amplifying its scientific visibility.

In conclusion, (+)-N-Deacetyllappaconitine (CAS 11033-64-0) represents a fascinating intersection of traditional knowledge and cutting-edge research. Its exploration addresses key questions in natural product drug discovery, while its pharmacological properties resonate with contemporary health trends. As interest in sustainable medicine grows, this compound may well emerge as a cornerstone in future therapeutic innovations.

Recommended suppliers
Essenoi Fine Chemical Co., Limited
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shaanxi pure crystal photoelectric technology co. LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shaanxi pure crystal photoelectric technology co. LTD
ASIACHEM I&E (JIANGSU) CO., LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
ASIACHEM I&E (JIANGSU) CO., LTD
Zhangzhou Sinobioway Peptide Co.,Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Zhangzhou Sinobioway Peptide Co.,Ltd.
Inner Mongolia Xinhong Biological Technology Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Inner Mongolia Xinhong Biological Technology Co., Ltd