• 1. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 2. Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor?
  Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
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  Polym. Chem., 2015,6, 5501-5502
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Phenylacetylindoles

1-[2-(3,4-Dimethoxyphenyl)Acetyl]-N-Ethyl-2,3-Dihydro-1H-Indole-2-Carboxamide (CAS No. 1100790-85-9)

1-[2-(3,4-Dimethoxyphenyl)Acetyl]-N-Ethyl-2,3-Dihydro-1H-Indole-2-Carboxamide, commonly referred to by its CAS number 1100790-85-9, is a complex organic compound with significant potential in the fields of pharmacology and material science. This compound belongs to the class of indole derivatives, which have been extensively studied due to their diverse biological activities and structural versatility. The molecule features a substituted indole ring system, an acetyl group attached to a dimethoxyphenyl moiety, and an ethylamino group, making it a valuable compound for both academic research and industrial applications.

The synthesis of 1-[2-(3,4-Dimethoxyphenyl)Acetyl]-N-Ethyl-2,3-Dihydro-1H-Indole-2-Carboxamide involves a series of carefully designed organic reactions. The starting material typically includes an indole derivative, which undergoes acetylation at the 2-position. This step is followed by the introduction of the ethylamino group at the 1-position of the indole ring. The presence of the dimethoxyphenyl group introduces steric and electronic effects that can significantly influence the compound's reactivity and biological properties. Recent advancements in catalytic methods have enabled more efficient and selective syntheses of such complex molecules, reducing production costs and improving yield.

Recent studies have highlighted the potential of CAS 1100790-85-9 as a promising candidate in drug discovery. The compound has shown remarkable activity in vitro against various enzymes associated with neurodegenerative diseases, such as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). These enzymes are key targets for developing treatments for Alzheimer's disease and related conditions. Preclinical studies suggest that the compound's unique structure allows it to cross the blood-brain barrier effectively, enhancing its bioavailability and therapeutic potential.

In addition to its pharmacological applications, 1-[2-(3,4-Dimethoxyphenyl)Acetyl]-N-Ethyl-2,3-Dihydro-1H-indole has also been explored for its role in materials science. Researchers have investigated its ability to form self-assembled monolayers (SAMs) on various substrates, which could be utilized in the development of advanced sensors and electronic devices. The compound's amphiphilic nature—owing to the hydrophilic dimethoxyphenyl group and hydrophobic indole core—makes it particularly suitable for such applications.

The structural complexity of CAS No. 1100790 presents both challenges and opportunities for further research. Computational studies using molecular docking techniques have provided insights into its binding interactions with target proteins, guiding future optimization efforts. Moreover, green chemistry approaches are being increasingly adopted to synthesize this compound sustainably, aligning with global efforts to reduce environmental impact.

In conclusion, 1-[2-(3,4-Dimethoxyphenyl)Acetyl]-N-Ethyl-related compounds represent a fascinating area of study with wide-ranging implications across multiple disciplines. As research continues to uncover new properties and applications of this compound, it is poised to make significant contributions to both medicine and technology.

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