Cas no 110-52-1 (1,4-Dibromobutane)

1,4-Dibromobutane (C?H?Br?) is a halogenated alkane commonly used as a versatile building block in organic synthesis. Its bifunctional structure, featuring reactive bromine atoms at both terminal positions, makes it valuable for nucleophilic substitution reactions, cyclization processes, and the preparation of polymers or pharmaceuticals. The compound exhibits high reactivity in alkylation and cross-coupling reactions, serving as a precursor for heterocycles, liquid crystals, and other specialty chemicals. With a molecular weight of 215.92 g/mol and a boiling point of ~198–200°C, it is typically supplied as a clear, colorless to pale yellow liquid. Proper handling is required due to its corrosive nature and potential lachrymatory effects.
1,4-Dibromobutane structure
1,4-Dibromobutane structure
Product Name:1,4-Dibromobutane
CAS No:110-52-1
MF:C4H8Br2
MW:215.914319992065
MDL:MFCD00000261
CID:35619
PubChem ID:8056
Update Time:2025-12-15

1,4-Dibromobutane Chemical and Physical Properties

Names and Identifiers

    • 1,4-Dibromobutane
    • tetramethylene bromide
    • 1,4-Dibromobutane,(Tetramethylene dibromide)
    • Tetramethylene dibromide
    • 1,4 DIBROMBUTANE
    • 1,4-bromobutane
    • 1,4-Butylene bromide
    • 1,4-DIBROMBUTAN
    • 1,4-Dibrombutan [German]
    • 1,4-dibrombutane
    • 1,4-dibromo-butane
    • 1,4-DIBROMOBUTANE FOR SYNTHESIS
    • 1,4-DIBROMOBUTENE
    • 1,4-dibromo-n-butane
    • Butane,1
    • DIBROMO BUTANE, 1,4-
    • TETRAMETYLENE DIBROMIDE
    • DBB
    • 4-DibroMobutane
    • BrCH2CH2CH2CH2Br
    • 1,4-dibromo-butan
    • α,ω-Dibromobutane
    • Dibromo-1,4 butane
    • Dibromobutane,98%
    • 1,4-Dibromo butane
    • CHEMBL3185714
    • EINECS 203-775-5
    • 1, 4-dibromo-butane
    • Butane,4-dibromo-
    • 1,4-bis(bromanyl)butane
    • 110-52-1
    • AKOS000118763
    • CAS-110-52-1
    • EN300-19289
    • UNII-G49PHR6JFU
    • BP-21423
    • NS00021514
    • 4-01-00-00267 (Beilstein Handbook Reference)
    • 1,3-Bis(chloroethylsulfonyl)propanol
    • Butane, 1,4-dibromo-
    • DTXCID3024364
    • Tox21_301070
    • MFCD00000261
    • Q161522
    • NCGC00254971-01
    • NCIOpen2_003230
    • NSC71435
    • NSC 71435
    • Q-200082
    • Tetramethylenebromide
    • 1,4-Dibromobutane, 99%
    • FT-0606854
    • D77910
    • 1, 4-dibromobutane
    • SCHEMBL8484
    • NSC-71435
    • A802208
    • AI3-14617
    • 1,4 dibromobutane
    • DIBROMOBUTANE, 1,4-
    • alpha,omega-Dibromobutane
    • G49PHR6JFU
    • AM20080049
    • 1,4-dibromobutan
    • F1908-0120
    • InChI=1/C4H8Br2/c5-3-1-2-4-6/h1-4H
    • CS-W020631
    • NCGC00248278-01
    • DTXSID5044364
    • BRN 1071199
    • WLN: E4E
    • D0176
    • 1.4-dibromobutane
    • 1,4dibromobutane
    • 1,4 -dibromobutane
    • CCRIS 8917
    • 1,4-Dibromobutane,97%
    • STL280306
    • 1,4-Dibromobutane; NSC 71435; Tetramethylene Dibromide; Tetramethylenebromide; a,?-Dibromobutane
    • 1,4Dibrombutan
    • BBL027293
    • Butane, 1,4dibromo
    • alpha,omegaDibromobutane
    • 203-775-5
    • MDL: MFCD00000261
    • Inchi: 1S/C4H8Br2/c5-3-1-2-4-6/h1-4H2
    • InChI Key: ULTHEAFYOOPTTB-UHFFFAOYSA-N
    • SMILES: BrCCCCBr
    • BRN: 1071199

Computed Properties

  • Exact Mass: 213.89900
  • Monoisotopic Mass: 213.899275
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 6
  • Rotatable Bond Count: 3
  • Complexity: 17.5
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.5
  • Topological Polar Surface Area: 0

Experimental Properties

  • Color/Form: Colorless or yellowish liquid.
  • Density: 1.808?g/mL?at 25?°C(lit.)
  • Melting Point: ?20?°C (lit.)
  • Boiling Point: 198°C
  • Flash Point: Degrees Fahrenheit:230°F
    Degrees Celsius:110°C
  • Refractive Index: n20/D 1.519(lit.)
  • Solubility: 0.35g/l
  • Water Partition Coefficient: Insoluble
  • Stability/Shelf Life: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
  • PSA: 0.00000
  • LogP: 2.55640
  • Sensitiveness: Sensitive to light and air
  • FEMA: 2069
  • Solubility: Soluble in chloroform, alcohol and ether, insoluble in water.

1,4-Dibromobutane Security Information

  • Symbol: GHS05 GHS06
  • Prompt:dangerous
  • Signal Word:Danger
  • Hazard Statement: H301,H315,H318,H335
  • Warning Statement: P261,P280,P301+P310,P305+P351+P338
  • Hazardous Material transportation number:UN 2810 6.1/PG 3
  • WGK Germany:2
  • Hazard Category Code: 25-37/38-41
  • Safety Instruction: S26-S39-S45-S37/39
  • RTECS:EJ7565000
  • Hazardous Material Identification: T
  • HazardClass:6.1(b)
  • PackingGroup:III
  • TSCA:Yes
  • Storage Condition:Store in a cool, dry place. Store in tightly closed containers.
  • Safety Term:6.1(b)
  • Packing Group:III
  • Risk Phrases:R25; R36/37/38; R41
  • Packing Group:III
  • Hazard Level:6.1(b)

1,4-Dibromobutane Customs Data

  • HS CODE:2903399090
  • Customs Data:

    China Customs Code:

    2903399090

    Overview:

    2903399090. Fluorination of other acyclic hydrocarbons\Brominated or iodinated derivatives. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:5.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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1,4-Dibromobutane Suppliers

Shandong Jing Kun Chemical Co.,Ltd.
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(CAS:110-52-1)1,4-DIBROMOBUTANE
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(CAS:110-52-1)1,4-Dibromobutane
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Tiancheng Chemical (Jiangsu) Co., Ltd
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Price ($):discuss personally

1,4-Dibromobutane Spectrogram

1H NMR 300 MHz DMSO
1H NMR
13C NMR
13C NMR

Additional information on 1,4-Dibromobutane

Chemical Profile of 1,4-Dibromobutane (CAS No. 110-52-1)

1,4-Dibromobutane, with the chemical formula C?H?Br?, is a significant organic compound widely utilized in synthetic chemistry and material science. This brominated alkane, identified by its CAS number 110-52-1, exhibits a unique molecular structure that makes it a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty polymers. The presence of two bromine atoms at the 1st and 4th carbon positions imparts distinct reactivity, enabling diverse chemical transformations that are pivotal for modern industrial applications.

The compound’s utility stems from its ability to undergo nucleophilic substitution reactions, cross-coupling reactions, and other functional group interconversions. In pharmaceutical research, 1,4-dibromobutane serves as a precursor for the development of novel therapeutic agents. Recent studies have highlighted its role in constructing complex molecular architectures essential for drug discovery. For instance, researchers have leveraged its reactivity to synthesize brominated heterocycles, which are known to exhibit potent biological activity. These findings underscore the importance of CAS no 110-52-1 in advancing medicinal chemistry.

In material science, 1,4-dibromobutane finds application in the synthesis of flame-retardant polymers and liquid crystals. Its bromine atoms enhance the thermal stability and fire resistance of polymer matrices, making it a preferred choice for high-performance materials used in electronics and construction industries. The compound’s compatibility with various polymerization techniques has led to the development of advanced composites with tailored properties. Such innovations reflect the growing demand for 1,4-dibromobutane in industrial applications driven by sustainability and safety considerations.

From an academic perspective, 1,4-dibromobutane has been extensively studied for its mechanistic insights into organic reactions. Its role as a dibromo intermediate has provided chemists with a deeper understanding of radical-mediated transformations and stereoselective synthesis. Researchers have employed computational methods to model the reactivity of CAS no 110-52-1, revealing novel pathways for optimizing synthetic routes. These advancements not only enhance laboratory efficiency but also contribute to the broader field of organic synthesis.

The pharmaceutical industry has particularly benefited from the versatility of 1,4-dibromobutane in drug development. Its incorporation into active pharmaceutical ingredients (APIs) has enabled the creation of compounds with improved pharmacokinetic profiles. For example, derivatives of this compound have been investigated for their antimicrobial and anti-inflammatory properties. The ongoing exploration of its pharmacological potential continues to inspire new research directions, reinforcing its significance in modern medicine.

Moreover, 1,4-dibromobutane plays a crucial role in agrochemical formulations. Its derivatives are used as intermediates in the synthesis of pesticides and herbicides that enhance crop protection strategies. The compound’s ability to introduce bromine atoms into target molecules allows for the development of agrochemicals with enhanced efficacy and environmental compatibility. This aligns with global efforts to promote sustainable agriculture while maintaining high yields.

The industrial production of CAS no 110-52-1 adheres to stringent quality control measures to ensure consistency and purity. Manufacturers employ advanced purification techniques such as distillation and crystallization to isolate high-purity grades suitable for sensitive applications. These processes are critical in maintaining the compound’s reactivity and performance across various end-use industries.

In conclusion, 1,4-dibromobutane is a multifaceted compound with far-reaching applications in pharmaceuticals, materials science, and agriculture. Its unique chemical properties continue to drive innovation across multiple scientific disciplines. As research progresses, new methodologies and applications will likely emerge, further solidifying its importance in industrial and academic settings.

Recommended suppliers
Shandong Jing Kun Chemical Co.,Ltd.
(CAS:110-52-1)1,4-DIBROMOBUTANE
C0018
Purity:99%
Quantity:200kg
Price ($):Inquiry
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:110-52-1)1,4-Dibromobutane
sfd16853
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email