Cas no 1092352-11-8 (tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate)
Technical Introduction:
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate is a versatile N-Boc-protected pyrrolidine derivative featuring a cyanomethyl substituent at the 2-position. This compound serves as a valuable intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and bioactive molecules. The tert-butoxycarbonyl (Boc) group offers excellent stability under basic conditions while allowing selective deprotection under acidic conditions, facilitating further functionalization. The cyanomethyl moiety provides a reactive handle for diverse transformations, including nucleophilic additions or reductions. Its well-defined structure and compatibility with standard synthetic protocols make it a practical choice for constructing complex heterocycles or chiral scaffolds. Suitable for use under inert conditions, it is typically handled as a neat liquid or in solution.
1092352-11-8 structure
Product Name:tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate
CAS No:1092352-11-8
MF:C11H18N2O2
MW:210.272822856903
MDL:MFCD12912059
CID:1089479
PubChem ID:17960263
Update Time:2025-06-23
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate
- DTXSID801192498
- SCHEMBL4093254
- 2-(cyanomethyl)-1-pyrrolidinecarboxylic acid tert-butyl ester
- N-Boc-2-cyanomethylpyrrolidine
- EN300-50914
- 1092352-11-8
- GSNDDHMLFYORQI-UHFFFAOYSA-N
- AS-36628
- 1,1-Dimethylethyl 2-(cyanomethyl)-1-pyrrolidinecarboxylate
- DA-17523
- AKOS015841638
- CS-0171779
- A807877
- tert-Butyl2-(cyanomethyl)pyrrolidine-1-carboxylate
- PB33661
- 1-BOC-2-(CYANOMETHYL)PYRROLIDINE
- MFCD12912059
- PB28280
- N-Boc-2-cyanomethyl-pyrrolidine
-
- MDL： MFCD12912059
- Inchi： 1S/C11H18N2O2/c1-11(2,3)15-10(14)13-8-4-5-9(13)6-7-12/h9H,4-6,8H2,1-3H3
- InChI Key： GSNDDHMLFYORQI-UHFFFAOYSA-N
- SMILES： O(C(C)(C)C)C(N1CCCC1CC#N)=O
Computed Properties
- Exact Mass: 210.136827821g/mol
- Monoisotopic Mass: 210.136827821g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 15
- Rotatable Bond Count: 4
- Complexity: 285
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.4
- Topological Polar Surface Area: 53.3?2
Experimental Properties
- Color/Form: Pale-yellow to Yellow-brown Liquid
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate Security Information
- Signal Word：Warning
- Hazard Statement： H302
- Warning Statement： P280;P305+P351+P338
- Storage Condition：Room temperature
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chemenu | CM196507-5g |
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate |
1092352-11-8 | 97% | 5g |
$772 | 2021-08-05 | |
| Alichem | A109008201-5g |
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate |
1092352-11-8 | 97% | 5g |
$835.12 | 2023-09-04 | |
| abcr | AB306956-250 mg |
1-Boc-2-(cyanomethyl)pyrrolidine; 97% |
1092352-11-8 | 250mg |
€306.80 | 2023-04-26 | ||
| abcr | AB306956-1 g |
1-Boc-2-(cyanomethyl)pyrrolidine; 97% |
1092352-11-8 | 1g |
€559.40 | 2023-04-26 | ||
| abcr | AB306956-5 g |
1-Boc-2-(cyanomethyl)pyrrolidine; 97% |
1092352-11-8 | 5g |
€1,107.50 | 2023-02-04 | ||
| TRC | B646323-10mg |
1-Boc-2-(cyanomethyl)pyrrolidine |
1092352-11-8 | 10mg |
$ 50.00 | 2022-06-07 | ||
| TRC | B646323-50mg |
1-Boc-2-(cyanomethyl)pyrrolidine |
1092352-11-8 | 50mg |
$ 95.00 | 2022-06-07 | ||
| TRC | B646323-100mg |
1-Boc-2-(cyanomethyl)pyrrolidine |
1092352-11-8 | 100mg |
$ 160.00 | 2022-06-07 | ||
| Chemenu | CM196507-5g |
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate |
1092352-11-8 | 97% | 5g |
$960 | 2023-11-25 | |
| Enamine | EN300-50914-0.05g |
tert-butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate |
1092352-11-8 | 0.05g |
$240.0 | 2023-02-10 |
tert-Butyl 2-(cyanomethyl)pyrrolidine-1-carboxylate Related Literature
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
-
Daniel Messmer,Stefan Salentinig,Jakob Heier Nanoscale, 2019,11, 6929-6938
-
Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
-
Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
-
Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
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