• 1. An intensified π-hole in beryllium-doped boron nitride meshes: its determinant role in CO2 conversion into hydrocarbon fuels?
  Luis Miguel Azofra,Douglas R. MacFarlane,Chenghua Sun Chem. Commun., 2016,52, 3548-3551
• 2. An automatic determination of thoria in thoria-urania mixtures
  Analyst, 1966,91, 208-210
• 3. Acentric and chiral heterometallic inorganic–organic hybrid frameworks mediated by alkali or alkaline earth ions: synthesis and NLO properties
  Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068
• 4. An atom efficient route to N-aryl and N-alkyl pyrrolines by transition metal catalysis?
  Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
• 5. An asymmetric supercapacitor based on controllable WO3 nanorod bundle and alfalfa-derived porous carbon?
  Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642

Acetic Acid; tert-butyl 4-carbamimidoylpiperidine-1-carboxylate: A Comprehensive Overview

The compound with CAS No. 1082950-23-9, commonly referred to as tert-butyl 4-carbamimidoylpiperidine-1-carboxylate, is a significant molecule in the field of organic chemistry. This compound has garnered attention due to its unique structural properties and potential applications in various industries. The molecule consists of a piperidine ring substituted with a carbamimidoyl group and a tert-butyl ester, making it a versatile building block for further chemical modifications.

Recent studies have highlighted the importance of tert-butyl 4-carbamimidoylpiperidine-1-carboxylate in drug discovery and development. Its structure allows for easy functionalization, enabling researchers to explore its potential as a precursor for bioactive compounds. For instance, the piperidine ring is known for its ability to form hydrogen bonds, which is crucial in drug-receptor interactions. This property has led to investigations into its role as a scaffold for designing novel pharmaceutical agents.

One of the most promising applications of this compound is in the synthesis of acetic acid derivatives. Acetic acid, a fundamental organic compound, finds extensive use in industries ranging from food production to pharmaceuticals. The tert-butyl ester group in the molecule facilitates controlled release of acetic acid during reactions, making it an ideal intermediate in the production of acetic acid-based products. This has been particularly useful in the development of eco-friendly chemical processes that minimize waste and improve efficiency.

Moreover, advancements in computational chemistry have enabled researchers to predict the reactivity and stability of tert-butyl 4-carbamimidoylpiperidine-1-carboxylate with greater accuracy. Quantum mechanical calculations have revealed that the molecule exhibits favorable electronic properties, which enhance its reactivity towards nucleophilic substitutions and other key organic reactions. These insights have paved the way for innovative synthetic strategies that leverage this compound's unique characteristics.

In terms of synthesis, tert-butyl 4-carbamimidoylpiperidine-1-carboxylate can be prepared via a variety of methods, including nucleophilic substitution and coupling reactions. One popular approach involves the reaction of piperidine derivatives with carbamimidoylating agents under specific conditions. The use of tert-butyl groups as protecting agents has been shown to significantly improve reaction yields and selectivity, making this method highly efficient.

The integration of tert-butyl 4-carbamimidoylpiperidine-1-carboxylate into medicinal chemistry has opened new avenues for developing bioactive molecules. For example, researchers have successfully utilized this compound as a starting material for synthesizing inhibitors of key enzymes involved in diseases such as cancer and neurodegenerative disorders. Its ability to modulate enzyme activity through strategic functionalization underscores its potential as a valuable tool in drug design.

Another area where this compound has shown promise is in materials science. The piperidine ring's ability to form stable amide bonds makes it an attractive candidate for designing polymeric materials with tailored properties. Recent studies have demonstrated that polymers derived from tert-butyl 4-carbamimidoylpiperidine-1-carboxylate exhibit excellent mechanical strength and thermal stability, making them suitable for applications in advanced composites and coatings.

In conclusion, tert-butyl 4-carbamimidoylpiperidine-1-carboxylate (CAS No. 1082950-23-9) is a multifaceted compound with significant potential across various scientific domains. Its structural versatility, combined with recent advancements in synthetic and computational techniques, positions it as a key player in future research and development efforts. As scientists continue to explore its properties and applications, this compound is poised to make substantial contributions to fields ranging from pharmaceuticals to materials science.

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